Depression Clinical Trial
Official title:
Hormonal Levels in Men With Major Depressive Disorder
Subjects will be 1000 men meeting the following inclusion criteria: 1) male, age 18-65
years; 2) meeting DSM-IV criteria for major depressive disorder within the past one year,
with a HAM-D score >12.
Subjects will be excluded if they exhibit 1) a substance abuse or dependence disorder within
the past year; 2) current psychotic symptoms; or 3) a history of bipolar disorder.
Procedure
After informed consent, eligible patients will have blood drawn for serum hormone levels;
cortisol, DHEA-S and testosterone or they will provide a salivary sample for measurement of
hormone levels.
We will also test hormone level form 1000 healthy males (from blood or saliva) at the same
age for comparison.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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