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Depression, Postpartum clinical trials

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NCT ID: NCT01463202 Completed - Contraception Clinical Trials

Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression

DEPO-ABCD
Start date: November 2011
Phase: Phase 4
Study type: Interventional

The investigators plan to enroll 184 women who are planning to breastfeed and use DMPA after delivery to find out whether the timing of postpartum administration of DMPA (prior to hospital discharge or 4-6 weeks after delivery) affects the duration or exclusivity of breastfeeding among women who plan to breastfeed their infants.

NCT ID: NCT01453114 Completed - Depression Clinical Trials

Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy

Start date: November 2008
Phase: N/A
Study type: Interventional

The overarching goal of this study is to adapt a cognitive behavioral prevention of recurrence treatment (CBT-PR) for women with a history of recurrent major depressive disorder who decide to discontinue their maintenance anti-depressant (AD) treatment for pregnancy.

NCT ID: NCT01452321 Completed - Clinical trials for Depression, Postpartum

Repetitive Transcranial Magnetic Stimulation in Postpartum Depression

rTMSPPD
Start date: August 2007
Phase: Phase 2
Study type: Interventional

Several factors characterize repetitive transcranial magnetic stimulation (rTMS) as a strategic aid in the treatment of postpartum depression. However, up to current days there have been no studies evaluating the effects of rTMS on neurocognitive and social performance of women suffering from the disorder. The present study evaluates the impacts of rTMS in clinical, cognitive and social performance.

NCT ID: NCT01407783 Completed - Clinical trials for Post-partum Depression

Systems of Care for New Moms: Integrating Depression Treatment

NUMOMS
Start date: August 2008
Phase: N/A
Study type: Interventional

NUMOMS involves collaboration between Nurses for Newborns Foundation and Washington University in St. Louis. This study explores the co-location of depression treatment within nurse home visitation and the organizational changes needed to maintain access to evidence-based treatment. Problem Solving Tools (PST) was chosen as the depression treatment because it is well suited for use by non-mental health specialists and for in-home treatment. It is also a brief treatment (4-8 sessions) takes a non-pathologizing approach.

NCT ID: NCT01386086 Completed - Clinical trials for Postpartum Depression

Aripiprazole and Resistant Postpartum Depression

Start date: June 2011
Phase: Phase 3
Study type: Interventional

Currently there are no controlled data on the management of postpartum depression that fails to respond to adequate antidepressant therapy. The investigators recently reported that a large number of patients responded to the addition of atypical neuroleptics after having failed antidepressant trials. Aripiprazole used adjunctively to antidepressants is effective in patients with resistant depression but it has not been studied in patients with resistant postpartum depression. The investigators propose to conduct a 6 week open-label study to assess the effectiveness and tolerability of aripiprazole used adjunctively to antidepressants in patients with resistant postpartum depression.

NCT ID: NCT01379781 Completed - Clinical trials for Postpartum Depression

Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression

Start date: August 2011
Phase: N/A
Study type: Interventional

Postpartum depression (PPD) is undertreated and the consequences of this are substantial for women and children. Studies show that infant cry/fuss and sleep behavior are associated with PPD, and that parenting interventions can change infant behavior, yet these findings have never been applied to PPD. In this study, the investigators are teaching parenting skills to increase infant nocturnal sleep and reduce fuss/cry behavior to women likely to develop PPD to see if the investigators can prevent the onset of this disorder.

NCT ID: NCT01312883 Completed - Clinical trials for Postpartum Depression

Mothers Avoiding Depression Through Empowerment Intervention Trial

MADE IT
Start date: September 2007
Phase: N/A
Study type: Interventional

Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of depressive symptoms in postpartum mothers by preparing and educating women about specific situational triggers of depressive symptoms, by bolstering personal and social resources, by enhancing self-management skills to buffer postpartum demands, and by increasing access to existing healthcare and community resources available to postpartum mothers.

NCT ID: NCT01309516 Completed - Clinical trials for Depression, Postpartum

Randomised Control Trial of a Complex Intervention for Postnatal Depression

Start date: May 2009
Phase: Phase 2
Study type: Interventional

The study aims to: 1. Develop a culturally appropriate psychosocial intervention 2. Test feasibility and acceptability of psychosocial intervention in women suffering from postnatal depression. Primary Hypothesis: Depressed mothers who will receive the group intervention will show significant improvements in terms of symptoms of depression. Design: Randomised controlled trial. Setting: Outpatient department of Civil hospital Karachi. Participants: A total of 84 depressed mothers will be randomised equally to an intervention group and a Treatment as usual control group. Interventions: The 12 session multimodal psychosocial intervention will be delivered to mothers in the intervention group over a three months period. Each session would take up to 45 minutes. Control group will receive standard postnatal follow-up. Outcome measures: Primary outcome measures would be mothers' scores on Edinburgh Postnatal Depression Scale (EPDS)and Hamilton Depression Rating Scale (HDRS).

NCT ID: NCT01217658 Completed - Clinical trials for Postpartum Depression

Measuring and Reducing Excessive Infant Crying

UTHealth THB
Start date: January 2011
Phase: N/A
Study type: Interventional

Excessive infant crying (EIC) is likely to increase the risk of child abuse. The investigators propose a randomized trial using an intervention based on recommendations of Karp. The investigators will systematically identify 170 term infants with EIC and conduct assessments in the home at 6-8 weeks age to test the hypothesis that the intervention reduces mean infant hours of night-time crying, increases maternal soothing behaviors and improves parental anxiety and depression.

NCT ID: NCT01178008 Completed - Clinical trials for Post-partum Depression

Pilot Study on the Use of Acupuncture for Postpartum Depression

Start date: May 2010
Phase: N/A
Study type: Interventional

The proposed study is a randomized controlled trial to examine the efficacy and safety of active acupuncture versus placebo acupuncture for the treatment of postpartum depression. The investigators hypothesis is that active acupuncture would be superior to placebo acupuncture in the short-term treatment of postpartum depression.