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Depression, Postpartum clinical trials

View clinical trials related to Depression, Postpartum.

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NCT ID: NCT03715218 Completed - Quality of Life Clinical Trials

Impact of Mothers Touch Program to Improve Maternal Health After Birth

Start date: January 21, 2018
Phase: N/A
Study type: Interventional

After the child birth most women experience major health issues such as depression, severe fatigue, back pain, perineal pain, mastitis, urinary or faecal incontinence, sexual problems and relationship problems with partners. That all lead to poorer emotional and mental health and factors contributing isolation, exhaustion and physical health problems. 'Sava Mahina (6-week period) is a traditional practice for postpartum women in India, which include special diet, lifestyle and supportive care. The current multicenter randomized controlled trial (RCT) aims to evaluate outcomes of Indian postpartum care on women.

NCT ID: NCT03709004 Not yet recruiting - Breastfeeding Clinical Trials

Pacifiers and Breastfeeding Among Mothers at Risk for Postpartum Depression

Start date: April 2019
Phase: N/A
Study type: Interventional

We will enroll 40 mother-infant dyads in a randomized trial exploring the effect of distribution of pacifiers during the birth hospitalization to mothers at high risk for postpartum depression on pacifier use, infant feeding, and maternal stress.

NCT ID: NCT03703219 Completed - Mood Clinical Trials

Impact of Mothers Touch Program on Women's Psychological Functioning

Start date: April 12, 2018
Phase:
Study type: Observational

The study investigates the effect of the Mothers Touch program on the psychological well-being of new mothers following 5 weeks of child birth. Mothers Touch Program is designed based on traditional Indian post-partum care given by trained carer in the family. Study was designed as cohort, including a randomised controlled trial.

NCT ID: NCT03665038 Recruiting - Clinical trials for Post Partum Depression

A Study to Assess the Safety and Efficacy of Brexanolone in the Treatment of Adolescent Female Subjects With Postpartum Depression

Start date: May 17, 2018
Phase: Phase 3
Study type: Interventional

This study is a multi-center, double-blind, placebo-controlled study evaluating the efficacy, safety, tolerability, and pharmacokinetics of Brexanolone in the treatment of adolescent female subjects with postpartum depression.

NCT ID: NCT03654261 Recruiting - Clinical trials for Postpartum Depression

1-Day CBT Workshops for PPD

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Postpartum depression (PPD) affects up to 20% of women and has profound effects on women and their families. Clinical practice guidelines recommend that the majority of women with PPD receive psychotherapy. The purpose of this pilot study is to successfully adapt and deliver a 1-day CBT workshop for depression to women with PPD, establish the feasibility of a study protocol, and generate an estimate of the treatment effect (as well as its variance) in this population for a later, large-scale study. A previously validated 1-day CBT workshop has been adapted for depression for use with women experiencing PPD and living in the community. 30 women will be randomized to active treatment (n=15) or a 12 week wait list (n=15) in each setting and compare changes in depression, mother-infant attachment, service utilization, quality of life, and offspring behaviour.

NCT ID: NCT03646539 Not yet recruiting - Depression Clinical Trials

RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood

Start date: August 30, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy of an evidence-based smartphone application (app) for the management of mood compared to treatment as usual alone among 135 women who have been discharged post-delivery from Labor and Delivery at Stanford Children's Health - Lucile Packard Children's Hospital. Using psychometrically validated surveys for depression, postpartum depression, and anxiety, this study will evaluate whether the smartphone app has a differential effect on the mental health of postpartum women as compared to treatment as usual.

NCT ID: NCT03638687 Recruiting - Bipolar Disorder Clinical Trials

Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers

Start date: May 2014
Phase:
Study type: Observational

Through a recent cross species translational experiment, researchers have identified a set of epigenetic marks capable of predicting postpartum depression with greater than 85% accuracy. The researchers are looking to identify a group of women from both the general population and those with a history of mood disorders who are at risk for postpartum depression and obtain brain imaging data at a postpartum time period prior to the onset of depressive symptoms and compare it with those obtained during depressive episodes. The researchers will also evaluate the efficacy of postpartum depression biomarker prediction.

NCT ID: NCT03615794 Recruiting - Clinical trials for Major Depressive Disorder

A Study of Pregnant and Postpartum Women With and Without Mood Disorders

Start date: October 1, 2017
Phase:
Study type: Observational

This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes. Participants will have psychiatric histories taken and will be monitored throughout pregnancy and during the postpartum period for the development of depressive or other mood episodes. Biological measures, including hormone levels, immunological measures, and growth factors will be collected. Environmental factors such as sleep deprivation and stress will also be measured. These factors will be considered in the setting of genetic and epigenetic data with the hope that investigators will ultimately be able to predict the onset of postpartum mood episodes in this vulnerable population.

NCT ID: NCT03596879 Recruiting - Insomnia Clinical Trials

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

PPD
Start date: July 18, 2018
Phase: N/A
Study type: Interventional

The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms. Additionally, the investigators will also determine the effectiveness of digital/internet-based Cognitive Behavioral Therapy for Insomnia (dCBTI) in reducing the risk for PPD.

NCT ID: NCT03593473 Enrolling by invitation - Anxiety Disorders Clinical Trials

Inhaled Oxytocin and HPA Axis Reactivity

Start date: December 2018
Phase: Phase 2
Study type: Interventional

Mothers who were enrolled in the Mood, Mother and Infant study will be eligible to participate in the 6-year follow-up maternal visit. At the time of this visit, mothers will be randomized to a single 24 IU dose of nasal oxytocin or placebo. Following administration of the study drug, women will participate in the Trier Social Stress Test (TSST), and blood samples will be collected to quantify HPA axis reactivity.