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Depression, Postpartum clinical trials

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NCT ID: NCT04964206 Recruiting - Labor Pain Clinical Trials

Neuraxial Labor Analgesia and Offspring Neurodevelopment

Start date: October 14, 2022
Phase:
Study type: Observational [Patient Registry]

How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring neurodevelopment.

NCT ID: NCT04950868 Recruiting - Clinical trials for Postpartum Depression

The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Start date: March 18, 2022
Phase: Phase 1
Study type: Interventional

Postpartum depression is a serious disorder that affects approximately 14% of women who have recently given birth. Postpartum depression is either an episode of major depressive disorder (only low periods) or bipolar disorder (periods of lows and highs). Untreated postpartum depression can negatively affect the mother, the infant and the family. Antidepressants are the most used treatments; however, for many women these drugs are not useful, resulting in a pressing need for effective treatments for postpartum depression. Lack of sleep is common after delivery and can trigger depression in some women. Quetiapine, a drug used for bipolar disorder, major depressive disorder and occasionally sleeplessness has not been well studied in postpartum depression. This study aims to find out how mothers tolerate the drug and whether it is effective for postpartum depression. Results of this study may help investigators carry out a larger study comparing quetiapine and placebo (a sugar pill) in postpartum depression.

NCT ID: NCT04940585 Active, not recruiting - Clinical trials for Post Partum Depression

ROSE in Sunset Park

Start date: March 4, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to learn more about pregnant women's' experience with Reach Out, Stay Strong, Essentials for mothers of newborns (ROSE) and to evaluate the effectiveness of the ROSE program in preventing and reducing post-partum depressive symptoms, decreasing stress, and increasing social support among pregnant women.

NCT ID: NCT04934488 Completed - Clinical trials for Postpartum Depression

Online Peer-Delivered 1-Day CBT Workshops for PPD

Start date: June 7, 2021
Phase: N/A
Study type: Interventional

A parallel group RCT with experimental (immediate workshop) and waitlist control (treatment 12 weeks later) groups will address our objectives. All participants will be asked to complete study questionnaires at baseline (T1, 3 weeks before the intervention/first workshop) and 12 weeks later (T2, just prior to the waitlist control/second workshop). Workshops will be delivered by trained peer leaders (women who have recovered from PPD). The study will aim to determine if online 1-day CBT-based workshops for PPD delivered by trained lay peers added to care as usual during the COVID-19 pandemic: (1) can improve PPD more than usual care alone, (2) are cost-effective, (3) can reduce the impact of common comorbidities and complications of PPD including anxiety, partner-relationship discord, social support, infant temperament, parenting stress, and poorer mother-infant attachment.

NCT ID: NCT04928742 Completed - Clinical trials for Postpartum Depression

Online PHN CBT for PPD

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine if online group CBT for PPD delivered by public health nurses is superior to postnatal care as usual in: a) acutely treating PPD, b) reducing relapse and recurrence, c) improving common comorbidities and complications of PPD including anxiety and the mother-infant relationship, and d) to determine if this treatment is cost-effective.

NCT ID: NCT04925765 Completed - Pregnancy Related Clinical Trials

Virtual Reality Biofeedback for Postpartum Anxiety and Depression

VITALISE
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to test patient feasibility and acceptability of virtual reality biofeedback program in postpartum women for anxiety and depression outcomes.

NCT ID: NCT04923698 Completed - Yoga Clinical Trials

Effect of Yoga on Postpartum Depression

Start date: January 24, 2019
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effect of yoga on postpartum depression. Subjects: Forty primipara women with postpartum depression (PPD) selected randomly from Kasr El Ainy University Hospital in Cairo complaining of postpartum depression at least one month after childbirth shared in this study.

NCT ID: NCT04913584 Completed - Clinical trials for Postpartum Depression

Peer Administered Online CBT for PPD

PL-OCBT
Start date: August 25, 2020
Phase: N/A
Study type: Interventional

Postpartum depression (PPD) affects up to one in five of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care. This is at least partly due to significant difficulties faced by women in accessing psychotherapies, their preferred treatment for PPD. Around the world, there is a significant lack of healthcare professionals trained to deliver CBT. This study will utilize a randomized controlled trial design (with wait-list controls) and recruit 174 participants to determine if women with a past history of PPD (i.e., lay peers) can be trained to deliver effective group CBT online to women currently struggling with PPD. If peers can be trained to provide effective CBT, more women would receive treatment and the burden of PPD on women, families, and the healthcare system would be significantly reduced.

NCT ID: NCT04908332 Completed - Breastfeeding Clinical Trials

Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home

KBM
Start date: July 22, 2021
Phase: N/A
Study type: Interventional

The objective of this randomized clinical trial will determine the effectiveness of nursing intervention (Kangaroo Baby Massage) on the interaction between mothers and premature, low birth weight infants at home The dyad mother- infant of the control group will receive Kangaroo position KP and the dyad mother- infant mothers of the intervention group will receive the Kangaroo Baby Massage KBM

NCT ID: NCT04860661 Recruiting - Clinical trials for Postpartum Depression

Esketamine on Postpartum Depression in Cesarean Section Women

EKET
Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This study was to explore the preventive effect of esketamine on postpartum depression in cesarean section, and to evaluate the safety of the drug