Socio-psychological Status of Healthcare Workers During SARS-CoV2 Pandemic

Depression, Anxiety Clinical Trial

Official title:

Socio-psychological Status of Healthcare Workers During SARS-CoV2 Pandemic

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04961372
• Other study ID #: ErzincanUniversity
• Status: Completed
• Start date: March 1, 2021
• Est. completion date: September 30, 2021

Study information

• Verified date: March 2022
• Source: Erzincan University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of our study is to investigate the presence of depression, anxiety and fear in healthcare workers during the SARS-CoV2 pandemic process, to evaluate their work and social life situations, as well as to evaluate the perspectives of the entire population towards hospital admission, surgery decision and vaccination.

Description:

Severe Acute Respiratory Syndrome - Corona Virus 2 (SARS-CoV2) was detected by the Chinese Center for Disease Control and Prevention on 7 January 2020 in a patient with atypical pneumonia in Wuhan, China, via a nasopharyngeal swab. On March 11, 2020, the World Health Organization declared it a "Pandemic". SARS-CoV2 quickly turned into a global epidemic, with a total of 134,957,021 confirmed cases and 2,918,752 deaths reported in April 2021.Since SARS-CoV2 is a highly contagious disease, the risk of infection in healthcare workers is quite high. In one of the earliest studies in Wuhan, 29 percent of patients (40 out of 138) were reported to be healthcare workers. A report from the American Centers for Disease Control and Prevention (CDC) stated that a total of 9,282 healthcare workers were diagnosed with COVID-19, including 27 deaths, between February 12 and April 9, 2020. Eleven to nineteen percent of COVID-19 cases have been identified as healthcare professionals.As the investigators have seen in studies of SARS or Ebola outbreaks, the sudden onset of an immediately life-threatening epidemic can place an extraordinary amount of pressure on healthcare workers. Increased workload, physical fatigue, inadequate personal equipment, nosocomial transmission, and having to make ethically difficult decisions can have dramatic effects on their physical and mental health. The weight of working conditions together with the risk of illness of their social environment and families can cause mental health problems such as fear and anxiety in healthcare workers.When an effective vaccination program is in place, population uptake should be as high as possible to achieve herd immunity. Vaccination hesitancy, defined as a delay in acceptance or rejection of vaccination despite the availability of vaccination services, is one of the barriers to this. It is a complex special case that varies with time, place, and vaccines. It is influenced by factors such as peace of mind, convenience, and trust. Vaccine hesitations have been identified as one of the ten global health threats of 2019.The aim of our study is to investigate the presence of depression, anxiety and fear in healthcare workers during the SARS-CoV2 pandemic process, to evaluate their work and social life situations, as well as to evaluate the perspectives of the entire population towards hospital admission, surgery decision and vaccination.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 333
• Est. completion date: September 30, 2021
• Est. primary completion date: September 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• All healthcare workers aged between 18-65 who works at Siran Government Hospital

Exclusion Criteria:

• Participants who did not agree to participate in the study

• Uncooperative participants

Related Conditions & MeSH terms

• Depression
• Depression, Anxiety

Intervention

Other:
• Survey
PHQ9 Depression Scale for evaluating depression, GAD7 Anxiety Score for evaluating anxiety, WSAS Score for evaluating Work and Social Adjustment

Locations

Country	Name	City	State
Turkey	Siran Government Hospital	Gumushane	Siran

Sponsors (1)

Lead Sponsor	Collaborator
Erzincan University

Country where clinical trial is conducted

Turkey, 

References & Publications (13)

Ashby B, Best A. Herd immunity. Curr Biol. 2021 Feb 22;31(4):R174-R177. doi: 10.1016/j.cub.2021.01.006. Epub 2021 Jan 12. — View Citation

CDC COVID-19 Response Team. Characteristics of Health Care Personnel with COVID-19 - United States, February 12-April 9, 2020. MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):477-481. doi: 10.15585/mmwr.mm6915e6. — View Citation

Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y, Xia J, Yu T, Zhang X, Zhang L. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 Feb 15;395(10223):507-513. doi: 10.1016/S0140-6736(20)30211-7. Epub 2020 Jan 30. — View Citation

Fontanet A, Cauchemez S. COVID-19 herd immunity: where are we? Nat Rev Immunol. 2020 Oct;20(10):583-584. doi: 10.1038/s41577-020-00451-5. — View Citation

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24. Erratum in: Lancet. 2020 Jan 30;:. — View Citation

Liu X, Kakade M, Fuller CJ, Fan B, Fang Y, Kong J, Guan Z, Wu P. Depression after exposure to stressful events: lessons learned from the severe acute respiratory syndrome epidemic. Compr Psychiatry. 2012 Jan;53(1):15-23. doi: 10.1016/j.comppsych.2011.02.003. Epub 2011 Apr 12. — View Citation

Lung FW, Lu YC, Chang YY, Shu BC. Mental Symptoms in Different Health Professionals During the SARS Attack: A Follow-up Study. Psychiatr Q. 2009 Jun;80(2):107-16. doi: 10.1007/s11126-009-9095-5. Epub 2009 Feb 27. — View Citation

MacDonald NE; SAGE Working Group on Vaccine Hesitancy. Vaccine hesitancy: Definition, scope and determinants. Vaccine. 2015 Aug 14;33(34):4161-4. doi: 10.1016/j.vaccine.2015.04.036. Epub 2015 Apr 17. — View Citation

Swaminathan S. The WHO's chief scientist on a year of loss and learning. Nature. 2020 Dec;588(7839):583-585. doi: 10.1038/d41586-020-03556-y. — View Citation

Thangaraju P, Venkatesan SJCMJ. WHO Ten threats to global health in 2019: Antimicrobial resistance. 2019;44(3):1150-1.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585. Erratum in: JAMA. 2021 Mar 16;325(11):1113. — View Citation

WHO. WHO Coronavirus (COVID-19) Dashboard [Web Page]. 2021 [updated 11.04.2021. WHO Coronavirus (COVID-19) Dashboard]. Available from: https://covid19.who.int/.

Wu P, Fang Y, Guan Z, Fan B, Kong J, Yao Z, Liu X, Fuller CJ, Susser E, Lu J, Hoven CW. The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk. Can J Psychiatry. 2009 May;54(5):302-11. — View Citation

* Note: There are 13 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Patient Health Questionnaire-9 Score	Depression Score.1-4 Minimal depression,5-9 Mild depression,10-14 Moderate depression,15-19 Moderately severe depression,20-27 Severe depression	6 Months
Primary	Generalised Anxiety Disorder Assessment Score	Anxiety Score. 0-4: minimal anxiety,5-9: mild anxiety,10-14: moderate anxiety,15-21: severe anxiety	6 Months
Primary	Work and Social Adjustment Score	Work and Social Adjustment Score. WSAS score above 20 appears to suggest moderately severe or worse psychopathology. Scores between 10 and 20 are associated with significant functional impairment but less severe clinical symptomatology. Scores below 10 appear to be associated with subclinical populations	6 Months