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Dentin Sensitivity clinical trials

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NCT ID: NCT04005417 Completed - Clinical trials for Dentine Hypersensitivity

Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity

Start date: January 8, 2018
Phase:
Study type: Observational

The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.

NCT ID: NCT03965039 Completed - Clinical trials for Dentin Hypersensitivity

A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity

Start date: July 8, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the efficacy (changes in dentinal hypersensitivity) and safety (oral soft tissue evaluation) after use of one of four dentifrices in subjects with pre-existing hypersensitivity over an 11-week period.

NCT ID: NCT03943095 Completed - Dentin Sensitivity Clinical Trials

Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity

Start date: May 13, 2019
Phase: Phase 2
Study type: Interventional

This exploratory study will characterize the efficacy profile of an experimental dual active 5 percent (%) potassium nitrate/0.454% stannous fluoride dentifrice, compared to a single active 0.454% stannous fluoride desensitizing dentifrice, over an 8-week treatment period.

NCT ID: NCT03851900 Completed - Clinical trials for Dentin Hypersensitivity

A Comparison of Long-Term Effectiveness of Two Desensitizing Products

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water). At least 150 teeth wil be treated with desensitizing products and placebo randomly one third usig TM, one third using SE and one third using placebo. The efficiency of the materials will be evaluated at baseline, 1 week, 1 month, 3 months and 6 months after treatment.

NCT ID: NCT03750851 Completed - Dentin Sensitivity Clinical Trials

CPP-ACPF and Laser's Effect on Dentin Hypersensitivity

Start date: June 11, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate fluoride paste (CPP-ACPF) associated with low level laser therapy (LLLT) in the symptomatology and on the quality of life of the individuals with dentin hypersensitivity in a randomized placebo-controlled clinical trial. Volunteers 18 to 50 years old with hypersensitive teeth were randomized into 4 groups: GPlacebo - positioning of the laser tip without light emission + placebo dentifrice; GCPPACPF - positioning of the laser tip without light emission + CPP-ACPF application; GLaser - laser tip positioning with light emission + placebo dentifrice; GLaserCPPACPF - positioning and light emission of the laser beam + CPP-ACPF.

NCT ID: NCT03637426 Completed - Dentin Sensitivity Clinical Trials

Effect of Nano-hydroxyapatite and LASER on Dentin Hypersensitivity

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of nanohydroxyapatite associated with low potency laser therapy in eliminating or reducing dentin hypersensitivity in a randomized placebo-controlled clinical trial. Volunteers 18 to 50 years old with hypersensitive teeth were randomized into 4 groups: GPLACEBO - positioning of the laser tip without light emission + placebo dentifrice; GnHAP - positioning of the laser tip without light emission + nano-hydroxyapatite; GLASER - laser tip positioning with light emission + placebo substance; GLASERnHAP - positioning by laser beam with light emission + nano-hydroxyapatite.

NCT ID: NCT03515902 Completed - Clinical trials for Dentine Hypersensitivity

The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity

Start date: June 18, 2018
Phase: N/A
Study type: Interventional

Tooth hypersensitivity due to dental erosion is one of the most common problem related to swimming in improper pH chlorinated pools. Because the teeth are exposed to acidic water for a long time, which cause the loss of dental hard tissue. Tooth hypersensitivity can lead to a negative effect on daily life such as dietary selection, maintaining optimal dental hygiene and beauty aspects. It has been found that using mouthguard while swimming can prevent the teeth directly contact to chlorinated water, so it can protect tooth structure and decrease tooth hypersensitivity. Moreover, using mouthguard with viscous products can seal the gaps between mouthguard and teeth which can help to protect tooth structure and decrease dental hypersensitivity more effectively. At present, there are many desensitizing products such as toothpaste, mouthwash and chewing gum. Desensitizing toothpaste is the most common over-the-counter (OTC) materials in desensitizing. Many research has endorsed the properties of desensitizing toothpaste that can reduce tooth tissue loss and helps to reduce tooth hypersensitivity effectively. So it can be hypothesize that when use the combination of mouthguard with desensitizing toothpaste, it might have synergistic effect on reducing tooth hypersensitivity in swimmers.

NCT ID: NCT03514290 Completed - Dentin Sensitivity Clinical Trials

Effect of Low-level Laser Therapy on Post-bleaching Sensitivity and Color Change

Start date: July 11, 2016
Phase: N/A
Study type: Interventional

Objective: The objective of this clinical study was to evaluate low-level laser (LLL) therapy in tooth sensitivity and in effecting color change after in-officer bleaching treatment across three weeks of treatment. Methods: Twenty-one volunteers were evaluated through the split-mouth model, so that the right and left maxillary/mandibular quadrants were randomized and allocated to one of two groups: GPLACEBO - the laser tip was positioned without the emission of light (placebo effect) + tooth bleaching with 35% hydrogen peroxide (HP); GLASER - treated with LLL + tooth bleaching with 35% HP. To assess tooth sensitivity, a modified visual analogue scale (VAS) was used after an evaporative stimulus (stimulated pain) and a daily pain questionnaire (unstimulated pain) was also applied. A spectrophotometer was used to measure the color. Three bleaching sessions were performed, with intervals of 7 days. Sensitivity results were tested using Friedman test for intra-group evaluation and Wilcoxon test for inter-group evaluation and ANOVA for color change.

NCT ID: NCT03434782 Completed - Dentin Sensitivity Clinical Trials

Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth

Start date: April 24, 2017
Phase: Phase 1
Study type: Interventional

To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.

NCT ID: NCT03403088 Completed - Tooth Sensitivity Clinical Trials

Non-carious Cervical Lesions and Treatments

NCCL
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This study will compare clinically the efficacy, time to action and duration of different treatments for patients with non-carious cervical lesions (NCCLs) that caused dentin hypersensitivity (DH).