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Dentin Sensitivity clinical trials

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NCT ID: NCT06463938 Recruiting - Dentin Sensitivity Clinical Trials

A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH

Start date: May 12, 2024
Phase: N/A
Study type: Interventional

Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects". DH has a prevalence rate ranging from 1.3% to 92.1%, commonly affecting old ages. The use of laser has opened new dimensions in the treatment of DH. To the author's knowledge, not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP. Therefore, this research aims to determine the effectiveness of Casein phospho peptide paste (CPP-ACP) used alone or combined with a diode laser (LASOTRONIX).

NCT ID: NCT06378255 Recruiting - Dentin Sensitivity Clinical Trials

Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Evaluate the safety and clinical efficacy of new dental desensitizers in the treatment of dentin sensitivity, including the relief of sensitivity symptoms and the duration of efficacy.

NCT ID: NCT06378008 Recruiting - Dentin Sensitivity Clinical Trials

A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Start date: April 16, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.

NCT ID: NCT06273930 Recruiting - Sensitivity, Tooth Clinical Trials

Reduction of Dentine Hypersensitivity After Use of Different Dentifrices

Dentrifices
Start date: February 1, 2024
Phase: Phase 1
Study type: Interventional

To assess the impact of the use of 5% Calcium Sodium Phosphosilicate or 8% Arginine dentifrices on dentinal hypersensitivity following non-surgical periodontal therapy in patients with periodontitis.

NCT ID: NCT06264453 Recruiting - Clinical trials for Dentin Hypersensitivity

A Study to Evaluate the Efficacy and Safety of KH001 in Patients With Dentin Hypersensitivity

Start date: March 19, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of KH001 in patients with dentin hypersensitivity.

NCT ID: NCT06154941 Recruiting - Clinical trials for Dentin Hypersensitivity

Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Dentin hypersensitivity is a drastic problem, which threaten many dental patients. According to the last published systematic review and meta analysis at 2019, the prevalence of dentin hypersensitivity is being 33.5% among the population. Moreover, it was determined that young adults with age range from 18 to 44 years exhibited high percentage (43.9%) of such problem

NCT ID: NCT05927831 Recruiting - Clinical trials for Dentin Hypersensitivity

Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp pain or discomfort that responses to certain stimuli, typically thermal, tactile, osmotic or chemical, due to exposed dentinal surface which can be explained by the hydrodynamic theory. The laser is a narrow, focused beam of light emitted to vaporise, fuse, melt, or seal dentinal tubules using laser heat to induce hydroxyapatite crystals for recrystallisation of the mineral component of dentine. The obliteration of dentinal tubules is caused by heat generated by laser beam which inhibits the transmission of the stimulus in the dentinal tubules. Grape seed extract contains proanthocyanidins (PA) which is able to bind to proline-rich proteins, like collagen, and contributes in enzyme proline hydroxylase activity that is essential for the biosynthesis of collagen in the dentin. The cross-linking action of collagen fibrils in dentin also able to prevent mineral loss.

NCT ID: NCT05923294 Recruiting - Clinical trials for Gingival Recession, Localized

Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in localized recessions of anterior and premolar teeth. In addition, it is aimed to compare the postoperative gingival thickness between the two techniques. The secondary aim is to search the effects of both techniques on periodontal parameters and to evaluate patient-centered outcomes.

NCT ID: NCT05882760 Recruiting - Sensitivity, Tooth Clinical Trials

Postoperative Sensitivity Following Placement With Different Restorative Materials In Vital Posterior Teeth

GCP
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

There is a lack of long-term clinical studies comparing different restorative materials; most of the available studies have only looked at class I cavities or examined post-operative sensitivity in non-caries cervical lesions. The purpose of this study is to measure postoperative sensitivity in clinical settings at 3-month intervals for class 1 and 2 direct posterior restoration

NCT ID: NCT05835453 Recruiting - Gingivitis Clinical Trials

At-home Bleaching Using Clear Aligners

Start date: April 14, 2023
Phase: N/A
Study type: Interventional

The aim of the present project is to clinically evaluate the bleaching effectiveness, tooth sensitivity, gingival irritation and patient´s satisfaction during a at-home bleaching with 10% carbamide peroxide using a conventional bleaching tray or a clear aligner.