Clinical Trials Logo

Dentin Sensitivity clinical trials

View clinical trials related to Dentin Sensitivity.

Filter by:

NCT ID: NCT06417580 Not yet recruiting - Dentin Sensitivity Clinical Trials

Effect of Pregabalin Gel in Controlling Cervical Dentin Hypersensitivity

Start date: May 28, 2024
Phase: Phase 2
Study type: Interventional

This randomized, double-blind, placebo-controlled clinical study aims to evaluate the effect of a gel formulation based on 10% of pregabalin in the treatment of HD and on the participants' quality of life. The sample calculation will be based on previous work. After selecting participants, the participants will be randomly assigned to the following groups: placebo control group (CG), potassium nitrate gel group (GNK) and pregabalin gel group (GPG). A questionnaire (QEDH-15) to assess the impact of desensitizing treatment on oral health-related quality of life (OHRQoL) will be applied at baseline (T0) and in the last sensitivity record (T6). Pain will be assessed using a visual analogue scale after evaporative stimulation with an air jet and tactile stimulation with an exploratory probe. Three desensitizing treatment sessions will be carried out, with an interval of 72 hours between them. Sensitivity recording will be performed at T0 (baseline), T1 (after the first session), T2 (after the second session), T3 (after the third session), T4 (7 days after the last session), T5 (one month after the last session) and T6 (3 months after the last session). Data will be collected and subjected to statistical analysis for parametric data (ANOVA followed by Student-Newman-Keuls) or non-parametric data (Friedman's ANOVA followed by Tukey). To analyze the impact on quality of life, the Friedman test will be used.

NCT ID: NCT06394557 Active, not recruiting - Tooth Sensitivity Clinical Trials

Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions

Start date: August 14, 2023
Phase: N/A
Study type: Interventional

Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS). We selected for this study, 47 patients with color 2M2 or darker (Using 0M1 - 5M3 Vita bleaching shade guide). We performed two bleaching sessions with an acidic 35% hydrogen peroxide gel with either a 1-week or 2-day interval. We recorded the TS up to 48 h with a VAS scale and the color at baseline and 30 days after bleaching with a value-oriented shade guide and a spectrophotometer. The risk and intensity of TS and the color change were compared between the two groups.

NCT ID: NCT06378255 Recruiting - Dentin Sensitivity Clinical Trials

Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Evaluate the safety and clinical efficacy of new dental desensitizers in the treatment of dentin sensitivity, including the relief of sensitivity symptoms and the duration of efficacy.

NCT ID: NCT06378008 Recruiting - Dentin Sensitivity Clinical Trials

A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Start date: April 16, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to confirm the clinical dentin hypersensitivity (DH) efficacy of a 5 percent (%) calcium sodium phosphosilicate (CSPS) toothpaste.

NCT ID: NCT06371092 Completed - Sensitivity, Tooth Clinical Trials

Efficacy of a Desensitizing Agent During At-home Bleaching

Start date: January 31, 2023
Phase: Early Phase 1
Study type: Interventional

The main objective of this study is to evaluate if the use of UltraEZ during at-home bleaching treatment is effective in reducing tooth sensitivity, as well as doesn't affect the degree of tooth bleaching.

NCT ID: NCT06359028 Active, not recruiting - Dentin Sensitivity Clinical Trials

Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Start date: March 25, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.

NCT ID: NCT06358924 Completed - Clinical trials for Tooth Hypersensitivity

Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability

Start date: November 13, 2021
Phase: Phase 4
Study type: Interventional

This study compared the effect of four different desensitizing agents on shade stability and dental hypersensitivity following dental bleaching procedure. The follow-up periods ranged from 24 hours to 1 year.

NCT ID: NCT06358911 Completed - Clinical trials for Tooth Hypersensitivity

A Clinical Study for the Effect of 4th Generation Poly AmidoAmine Dendrimer on Post-Bleaching Hypersensitivity and Shade Stability

Start date: November 13, 2021
Phase: Phase 4
Study type: Interventional

This study assessed the impact of four desensitizing agents on both color stability and dental sensitivity following a bleaching procedure, spanning from the 24-hour to the 1-year follow-up assessment periods.

NCT ID: NCT06354270 Active, not recruiting - Dentin Sensitivity Clinical Trials

A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Start date: April 11, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.

NCT ID: NCT06288776 Completed - Tooth Sensitivity Clinical Trials

Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients. Participants aged 20 years and above having Gingival Index score 3 will be included in the study. Their tooth sensitivity will be checked initially and then they will be given Herbal based mouthwash for 3 months. Again, their tooth sensitivity shall be checked after 3 months.