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Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

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NCT ID: NCT05230797 Not yet recruiting - Pulp Necroses Clinical Trials

Zincoxide-propolis vs Zincoxide-eugenol Pulpectomy

Start date: April 2022
Phase: Early Phase 1
Study type: Interventional

The clinical trial aims to evaluate the clinical and radiographic success of Zinc oxide- propolis versus Zinc oxide -Eugenol as obturating material in pulpectomy of non-vital primary teeth.

NCT ID: NCT05181813 Completed - Pulp Necroses Clinical Trials

Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols

Start date: October 17, 2020
Phase: N/A
Study type: Interventional

This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp

NCT ID: NCT05146713 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Start date: January 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using 20mg/ml propolis nanoparticles extract solution during chemo-mechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

NCT ID: NCT05057325 Completed - Pulp Necroses Clinical Trials

Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold file ( reciprocation movement)

NCT ID: NCT05021809 Recruiting - Clinical trials for Necrotic Pulp With Symptomatic Apical Periodontitis

Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .

Start date: July 25, 2021
Phase: Phase 4
Study type: Interventional

Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of post-treatment symptoms. Calcium hydroxide has a pain-controlling effect at different times when compared to non-intracanal medication . Aim: The aim of the study to compare between postoperative pain after using two formulations of calcium hydroxide intracanal medication with and without iodoform .

NCT ID: NCT04983524 Completed - Necrotic Pulp Clinical Trials

Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp

Start date: October 2015
Phase: N/A
Study type: Interventional

Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide. The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.

NCT ID: NCT04942158 Active, not recruiting - Clinical trials for Dental Pulp Necrosis

Non-instrumentation Root Canal Treatment of Primary Molars

EndoDecide-1
Start date: October 4, 2021
Phase: N/A
Study type: Interventional

This randomized clinical trial intended to evaluate the efficacy of a technique of root canal treatment of deciduous molars with non-instrumentation of root canals and use of a paste containing antibiotics (chloramphenicol and tetracycline) and zinc oxide and eugenol (CTZ group). The hypothesis is that the efficacy of non-instrumentation treatment is non-inferior than the standard treatment involving manual instrumentation of root canals and filling with zinc oxide and eugenol paste (ZOE group) after 24 months of follow-up. Children will be randomly allocated to one of the two groups: CTZ group or ZOE group. In the CTZ group, after the location of root canals entrance, an initial irrigation will be conducted using 1% sodium hypochlorite. Then, CTZ paste will be placed in the pulp chamber floor, over the root canal entrances. The instrumentation of the root canals will not be performed for children allocated to this group. For the ZOE group, manual instrumentation with endodontic K files will be performed, aided by irrigation with 1% sodium hypochlorite. After the end of the instrumentation, root canals will be filled with ZOE paste. All teeth will be restored with bulk-fil resin composite. Children will be followed-up for 6, 12, 18 and 24 months after the treatment. The primary endpoint will be the success of endodontic treatment evaluated by clinical and radiographic methods after 24 months. Based on a non-inferiority limit of 15% in the success rate, it was estimated an anticipated sample size of 218 (109 per group), divided among the centers. Other secondary endpoints will be clinical time spent with the treatments, children's behavior during the treatment, discomfort immediately after the end of the treatment reported by the children, post-operative pain, improvement in the negative impact of Oral Health-Related Quality of Life, costs and cost-efficacy.

NCT ID: NCT04728386 Not yet recruiting - Necrotic Pulp Clinical Trials

Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite

Start date: January 2021
Phase: N/A
Study type: Interventional

This study aims to compare the effect of 2% curcumin solution versus 2.5% sodium hypochlorite as irrigating solutions in necrotic mandibular molars in terms of postoperative pain and antibacterial effect.

NCT ID: NCT04672070 Active, not recruiting - Dental Caries Clinical Trials

Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis

Start date: May 31, 2019
Phase: N/A
Study type: Interventional

The study design is a randomized controlled trial and up to 120 teeth, 50 in each of the 2 groups, will be enrolled from the patients at the National University Centre for Oral Health Singapore (NUCOHS) Endodontic unit. The primary aim of this study is to compare the efficacy of selective caries removal (SCR) and pulpotomy in preventing pulp necrosis and apical periodontitis in teeth with deep dental caries radiographically extending at least 2/3 into the width of dentine, over a review period of 6 months, 1, 3, and 5 years. The secondary aim of this study is to compare the costs (tangible i.e. restorative treatment costs, and intangible i.e. number of treatment visits and time spent at clinic to complete treatment) and tooth survival in the oral cavity, between teeth treated with SCR and pulpotomy.

NCT ID: NCT04646538 Completed - Necrotic Pulp Clinical Trials

Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Start date: June 5, 2017
Phase: Early Phase 1
Study type: Interventional

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.