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Dementia, Mild clinical trials

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NCT ID: NCT06417333 Completed - Dementia, Mild Clinical Trials

A Smart-wrist Band Connected Mobile Application for the Assessment and Management of Dementia Symptoms

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

In this study, we developed a mobile application that will enable caregivers to continuously monitor the vital health, medication, activity, and location of the patients with MCI with a smart wristband while enabling them caregivers to track the progress of the disease by a machine learning model that predicts MMSE of the patient using speech

NCT ID: NCT05240664 Completed - Dementia, Mild Clinical Trials

Effects of An ACP Programme for Older People With Early Dementia

Start date: January 9, 2021
Phase: N/A
Study type: Interventional

Advance care planning (ACP) has been widely advocated for persons with early stage dementia (PWEDs). This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP programme "Have a Say" for this population. It is hypothesized that participants in the intervention group will be more engaged in ACP and their dyadic concordance on end-of-life care preference with their family caregivers will be significantly higher than that in the control group.

NCT ID: NCT05187117 Completed - Depression Clinical Trials

CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners

Start date: March 9, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to test the adapted protocol, CAPABLE Family which builds upon the evidenced based CAPABLE program to address older adults with co-occurring physical disability and mild cognitive impairment or early stage dementia and the older adults' caregivers. It will consist of two phases - an open label pilot and waitlist control trial.

NCT ID: NCT05102201 Completed - Clinical trials for Cognitive Impairment

Effect of the Group-based Paro Intervention on Physiological and Psychological Outcomes

Start date: March 22, 2022
Phase: N/A
Study type: Interventional

This project contains three studies. This study will use a pilot randomized controlled trial to examine the effect of Paro (social robot) intervention on oxytocin, dopamine, and HRV variations and mental well-being for specific attachment older adults with dementia. A randomized controlled trial, single-blind, two parallel groups, and repeated measures design were used to examine the effects of Paro intervention on neurobiologically changes and mental well-being for specific attachment older adults with dementia before, during, and after the intervention.

NCT ID: NCT04950998 Completed - Clinical trials for Mild Cognitive Impairment

Smartphone App to Improve Physical Activity in Older Adults With MCI/Mild Dementia

Start date: December 5, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and test a physical activity-tracking smartphone app designed to facilitate physical activity in older adults with mild cognitive impairments or mild dementia. The app targets provides tips, messages, and strategies to overcome common barriers older adults face to being physically active. Participants will include older adults with memory or thinking problems or those diagnosed with mild cognitive impairment or mild forms of dementia who are smartphone users age 65 years or older and who are not meeting nationally recommended levels of physical activity. In the clinical trial phase of this study, 15 participant-study partner dyads will be oriented to the app and use it for a two-month period. Dyads will keep a diary to document their experiences and participants' activity patterns will also be tracked at the beginning and end of the study. After the two-month app trial is complete, dyads will return for a follow-up interview to discuss their experiences and provide suggestions for app improvements. Findings from this stage of the overall study will be combined with previous study phases to derive specifications for an optimized app for older people with mild cognitive impairments or mild dementia.

NCT ID: NCT04648735 Completed - Clinical trials for Mild Cognitive Impairment

Driving Evaluation and Fitness for Persons With Cognitive Impairments

Start date: August 1, 2015
Phase: N/A
Study type: Interventional

Driving is an important activity for older adults because it frequently relates to personal independence and wellbeing. This study compared the driving behaviors of older drivers with normal cognition and with MCI in unfamiliar driving situations and difficult maneuvers, and explored the practice effect on driving performance of drivers with MCI. This study used an observational, cross-section research design.

NCT ID: NCT04531956 Completed - Dementia Clinical Trials

Implementation of a Diagnostic Decision-aid for People With Memory Complaints and Their General Practitioners

S-DeciDeD
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

In a mixed-methods design the investigators will study decision making processes and experiences regarding a diagnostic trajectory before and after the introduction of a patient decision aid for people with memory complaints, their significant others and their GPs. The 'before group' will receive diagnostics as usual from their GPs. The 'after group' will use the patient decision aid. The investigators expect the patient decision aid to increase the level of SDM and to contribute to a timely and personalized diagnostic trajectory. Data will be collected using semi-structured interviews, questionnaires and information retrieved from people with memory complaints' medical records.

NCT ID: NCT04513106 Completed - Clinical trials for Mild Cognitive Impairment

Promoting Advance Care Planning for Persons With Early-stage Dementia in the Community: a Feasibility Trial

Start date: September 9, 2019
Phase: N/A
Study type: Interventional

Advance care planning (ACP) has been widely advocated to persons with early stage dementia (PWEDs). This feasibility trial aims to test a theory-based ACP programme "Have a Say" specifically designed for this population, which is underpinned by the Bandura's self-efficacy model. It is the first of its kind in Hong Kong and will be conducted in the community through medical-social collaboration. The aim of this study is to test the feasibility and preliminary effects of the "Have a Say" programme. It is hypothesized that participants in the intervention group will be more engaged in ACP and their dyadic concordance on end-of-life care preference with their family caregivers will be significantly higher than that in the control group.

NCT ID: NCT04491578 Completed - Clinical trials for Mild Cognitive Impairment

An Advance Care Planning Programme for Persons With Early Stage Dementia in the Community

Start date: January 9, 2021
Phase: N/A
Study type: Interventional

Advance care planning (ACP) has been widely advocated for persons with early stage dementia (PWEDs) and persons with mild cognitive impairment (MCI). This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP programme "Have a Say" for this population. It is hypothesized that participants received the intervention will be more engaged in ACP and their dyadic concordance on end-of-life care preference with their family caregivers will be higher after the intervention.

NCT ID: NCT03692988 Completed - Depressive Disorder Clinical Trials

Dignity Therapy for Patients With Early Dementia and Their Family

DTD
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Developed by Harvey M. Chochinov in 2005, Dignity Therapy (DT) invites individuals with life-limiting illnesses to reflect on matters of importance to them and compiles them in a narrative document for the patient to share. DT has shown to improve quality of life and a sense of dignity, as well as supporting relatives in the process of grievance. Featuring a gradual loss of memories of the past, decline of cognitive functions and awareness of self, dementia can be regarded as a life-limiting or life-changing illness, which is often accompanied by significant psychological stress. DT may help patients and their relatives reduce this stress. Yet, no studies have been conducted to determine the benefits of DT in patients with early stage dementia (ESD). This study investigates the feasibility and acceptance of DT by patients with (very) mild dementia (CDR: 0.5 - 1.5) and their relatives, as well as their overall satisfaction. This study further seeks to determine the effects of DT on sense of dignity, quality of life, dyadic coping, and levels of anxiety and depression in a randomized controlled design.