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Deep Vein Thrombosis clinical trials

View clinical trials related to Deep Vein Thrombosis.

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NCT ID: NCT00623987 Completed - Clinical trials for Deep Vein Thrombosis

Absence of Residual Vein Thrombosis Permits to Withdrawn Oral Anticoagulants

Exten-DACUS
Start date: June 1999
Phase: Phase 4
Study type: Interventional

Background. The optimal duration of oral anticoagulant treatment in patients with idiopathic Deep Vein Thrombosis (DVT)of the lower limbs is still uncertain. Residual Vein Thrombosis (RVT) has been found able to establish the patient' risk for recurrent thrombotic events. In the present study we conducted a RVT-based therapeutic strategy, withholding OAT after 3 months in patients without RVT while continuing anticoagulants for at least additional 9 months in those in whom RVT persists. Methods Patients with a first episode of symptomatic unprovoked proximal Vein Thrombosis (VT) were given Oral Anticoagulant Treatment (OAT) for 3 months. Residual Vein Thrombosis (RVT), ultrasonographically-detected, will be then assessed. Patients without RVT did not continue OAT (Group B), whereas those with RVT will continue OAT for at least additional 9 months. Patients were followed-up prospectively focusing on the study outcomes: occurrence of recurrent venous thromboembolism and major bleeding over a period of at least 12 months after OAT discontinuation.

NCT ID: NCT00588757 Not yet recruiting - Trauma Clinical Trials

Comparison Between Two Optional IVC Filters Regardind Ease of Use,Complications and Outcome

Start date: March 2008
Phase: N/A
Study type: Interventional

OptEase filters are easier to retrieve but the dwell time is shorter than the Gunter filters. There are more thrombi on the OptEase than on the Gunter at the time of retrieval. OptEase filter has a better infitration capabillity due to its diamond shape. OptEase filters will hjave more IVC occlusions as a complication.

NCT ID: NCT00550082 Completed - Cancer Clinical Trials

3 Screen Electronic Alert

Start date: July 2007
Phase: N/A
Study type: Observational

Evaluation of physician responses to BICS-Clinical Information 3-screen alerts that informs the clinician that his/her patient may be eligible for thromboprophylaxis.

NCT ID: NCT00549705 Completed - Pulmonary Embolism Clinical Trials

Registry of Hospitalized Patients Treated With Fondaparinux

Start date: July 2007
Phase: N/A
Study type: Observational

Registry of Hospitalized patients at Brigham and Women's Hospital treated with Fondaparinux

NCT ID: NCT00511173 Completed - Atrial Fibrillation Clinical Trials

Comparison of Warfarin Dosing Using Decision Model Versus Pharmacogenetic Algorithm

Start date: August 2006
Phase: Phase 4
Study type: Interventional

This is a prospective comparison of clinician dosing and a pharmacogenetic algorithm in diagnosed patients requiring warfarin therapy.

NCT ID: NCT00456196 Completed - Cancer Clinical Trials

Epidemiology of Venous Thromboembolism

Start date: April 2006
Phase: N/A
Study type: Observational

More than 5 years ago the DVT FREE Registry was conceived. Its database consists of 5,451 ultrasound-confirmed DVT patients from 183 institutions. This database is rich in information of critical importance to health care providers. The information contained within the database will be revisited to provide more detailed analyses which will be used for risk factor assessment and for decision-making regarding the implementation of VTE Prophylaxis.

NCT ID: NCT00452530 Completed - Pulmonary Embolism Clinical Trials

Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery

ADVANCE-2
Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn whether apixaban prevents the development of blood clots in the leg (deep vein thrombosis) and lung (pulmonary embolism), which sometimes occur after knee replacement surgery, and to compare the efficacy of apixaban with that of enoxaparin (Lovenox®) in the prevention of these clots. The safety of apixaban will also be studied.

NCT ID: NCT00450645 Recruiting - Cancer Clinical Trials

Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis

Cancer-DACUS
Start date: March 2005
Phase: Phase 4
Study type: Interventional

The duration of anticoagulant treatment in cancer patients with Deep Vein Thrombosis (DVT) of the lower limbs is still uncertain. The present study addresses the possible role of the Residual Vein Thrombosis (RVT) for establishing the optimal duration of Low Molecular Weight Heparin (LMWH). Patients with a first episode of symptomatic unprovoked or provoked proximal DVT will received LMWHs for 6 months; RVT, ultrasonographically-detected, will be then assessed. Patients without RVT stop LMWH, whereas those with RVT will be randomized to either stop or continue OAT for additional 6 months. Patients were followed-up at least 1 year after anticoagulant discontinuation focusing on the study outcomes: occurrence of recurrent venous thromboembolism and major bleeding

NCT ID: NCT00438230 Completed - Clinical trials for Deep Vein Thrombosis

Residual Vein Thrombosis Establishes the Optimal Duration of Oral Anticoagulants

DACUS
Start date: November 2003
Phase: Phase 4
Study type: Interventional

ABSTRACT Background The optimal duration of oral anticoagulant treatment in patients with idiopathic venous thromboembolism is still uncertain . The present study addressed the possible role of the Residual Vein Thrombosis in assessing the need for a prolonged anticoagulation. Methods Patients with a first episode of symptomatic unprovoked or provoked proximal Vein Thrombosis (VT) were given Oral Anticoagulant Treatment (OAT) for 3 months. Residual Vein Thrombosis (RVT), ultrasonographically-detected, will be then assessed. Patients without RVT did not continue OAT, whereas those with RVT will be randomized to either stop or continue OAT for 9 more months. Patients were followed-up prospectively focusing on the study outcomes: occurrence of recurrent venous thromboembolism and major bleeding over a period of at least 12 months after OAT discontinuation.

NCT ID: NCT00428129 Terminated - Clinical trials for Deep Vein Thrombosis

Microplasmin Administered Via the Trellis-8 Infusion System for Treatment of Acute Iliofemoral DVT

MAX-DVT
Start date: March 2007
Phase: Phase 2
Study type: Interventional

A single centre, single-arm study to evaluate safety and efficacy of microplasmin administration via the Trellis-8 Infusion System in patients with acute iliofemoral DVT