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Death, Sudden, Cardiac clinical trials

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NCT ID: NCT00382928 Completed - Clinical trials for Ventricular Fibrillation

Automatic External Defibrillation Monitoring in Cardiac Arrest

Start date: October 2006
Phase: Phase 1
Study type: Interventional

We propose to randomize automatic external cardioverter/defibrillators (AECD) in patients who are at high risk for life-threatening abnormal heart rhythms (arrhythmias) and are admitted to the telemetry ward, all other treatments being constant including cardiopulmonary resuscitation. We hypothesize that the automatic, rapid, accurate and specific diagnostic and therapeutic technology used in AECDs will further increase the rate of survival in patients with cardiac arrest through rapid and automatic defibrillation, independent of operator initiation, as compared to standard cardiopulmonary resuscitation initiated by healthcare providers.

NCT ID: NCT00376532 Completed - Arrythmia Clinical Trials

Extracellular Matrix Marker of Arrhythmia Risk (EMMA)

EMMA
Start date: September 2006
Phase: N/A
Study type: Observational

Assess whether serum levels of MMP 2 and or MMP 9 correlate with episodes of ventricular tachycardia or fibrillation in patients who have implantable cardioverter defibrillator devices.

NCT ID: NCT00312624 Completed - Cardiomyopathy Clinical Trials

Morphological Predictors of Sudden Cardiac Death in Patients With Known Cardiomyopathies

Start date: April 2006
Phase: N/A
Study type: Observational

This is a pilot study to find a correlation between MRI and ICD therapy in patients with known cardiomyopathies, aiming to determine if cardiac scarring identified by MRI correlates with ventricular arrhythmias and the occurrence of ICD therapy.

NCT ID: NCT00311181 Completed - Clinical trials for Sudden Cardiac Death

POWER (Pulse Width Optimized Waveform Evaluation Trial)

Start date: August 2006
Phase: Phase 4
Study type: Interventional

The objective of this study is to compare the ULV (Upper Limit of Vulnerability)/DFT (Defibrillation Threshold) efficacy between the 2.5, 3.5 and 4.5 ms membrane time constant based biphasic defibrillation waveforms. This comparison will result in identifying the optimal membrane time constant when programming the "tuned" defibrillation waveform.

NCT ID: NCT00296543 Completed - Clinical trials for End Stage Renal Disease

T Wave Alternans in Hemodialysis

Start date: October 2005
Phase: N/A
Study type: Observational

The purpose of this study is to determine if the hemodialysis procedure changes the risk for cardiac arrest in patients.

NCT ID: NCT00259025 Completed - Clinical trials for Renal Failure, Chronic

Intravenous n-3 Fatty Acids and Sudden Cardiac Death in Hemodialysis Patients

Start date: September 2006
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to investigate whether intravenous infusion of a lipid emulsion with a high content of n-3 polyunsaturated fatty acids can improve heart rate variability and ventricular repolarization and reduce ventricular arrhythmias in hemodialysis patients.

NCT ID: NCT00251134 Completed - Clinical trials for Myocardial Infarction

OMEGA-Study: Effect of Omega 3-Fatty Acids on the Reduction of Sudden Cardiac Death After Myocardial Infarction

OMEGA
Start date: October 2003
Phase: Phase 3
Study type: Interventional

Cardiovascular disease (CVD) is the leading cause of death in North America and Europe. The major cause of CVD is atherosclerosis like coronary artery disease (CAD). The results of recent trials hint that the course of CAD may be positively influenced by an increased intake of omega 3-fatty acids. The OMEGA-Trial analyses this effect in subjects who suffered an acute myocardial infarction. They are divided into two groups, both receiving standard post-infarction therapy. The subjects of one group additionally receive 1 gram of omega 3-fatty acids daily for a time-period of 12 months, while the subjects in the second group receive 1 gram olive-oil as placebo. Within the period of 12 months all events are reported and used to analyse the efficacy and safety of the additional therapy with omega 3-fatty acids.

NCT ID: NCT00241800 Completed - Clinical trials for Cardiovascular Diseases

Medications and the Risk of Sudden Cardiac Death

Start date: September 2005
Phase: N/A
Study type: Observational

To investigate a potential relationship between four different classes of non-cardiovascular drugs and the risk of sudden cardiac death.

NCT ID: NCT00231738 Completed - Clinical trials for Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease

Protective Effect of EPA on Cardiovascular Events

Start date: November 1996
Phase: Phase 4
Study type: Interventional

The purpose of this study was to test the hypothesis that the long-term use of highly (>98%) purified EPA, in addition to HMG-CoA reductase inhibitor (statin), would be more effective than statin alone in preventing cardiovascular events in Japanese patients with hypercholesterolemia.

NCT ID: NCT00226681 Completed - Clinical trials for Sudden Cardiac Arrest

Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD)

Start date: September 1999
Phase: Phase 1
Study type: Interventional

To determine if an education and support nursing intervention program helped sudden cardiac arrest survivors adjust to the event and to getting an ICD