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Renal Failure, Chronic clinical trials

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NCT ID: NCT05787080 Completed - Clinical trials for Restless Legs Syndrome

Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)

RLS
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study; It will be done to evaluate the presence of oxidative stress and its effects on lipid peroxidation products and antioxidant parameters after massage application and the possible effects of the appropriate massage protocol applied to the patients on oxidative stress in hemodialysis patients with restless legs syndrome.

NCT ID: NCT05769686 Completed - Surgery Clinical Trials

Laparoscopic Donor Nephrectomy Score, a New Scoring System for Preoperative Prediction of Difficulty of Laparoscopic Donor Nephrectomy

LAPDOCTOR
Start date: May 12, 2020
Phase:
Study type: Observational

The goal of this multicenter observational study is to develope and validate a new scoring system for preoperative prediction of difficulty of Laparoscopic Donor Nephrectomy. Healthy living kidney donors will be enrolled. The main questions it aims to answer are: 1) can the investigators predict difficulty of the operation ? 2) Can the investigators score difficulty based on this new scoring system? Difficulty of LDN will be graded by the operating surgeon at the end of the operation based on intraoperative predefined parameters. All operations will be blindly scored by the operating surgeon, while one radiologist will blindly review all preoperative CT scans. LAPDOCTOR scores will be compared with the degrees of difficulty assigned by the operating surgeon to investigate the match rate.

NCT ID: NCT05585268 Completed - Hypertension Clinical Trials

Electronic Decision Support for Deprescribing in Patients on Hemodialysis

MedSafer-HD
Start date: October 3, 2022
Phase: N/A
Study type: Interventional

Dialysis patients are prescribed an average of 10-12 medications per day, from up to 4-5 different clinicians and have the heaviest pill burden of all chronic conditions given their degree of comorbidity. One strategy for addressing the problem of "medication overload" is through scalable deprescribing interventions. MedSafer is an electronic deprescribing tool that cross-references patient health data with existing deprescribing guidelines and provides a deprescribing report to clinicians to facilitate deprescribing and reducing the burden of polypharmacy. In this study the investigators will test MedSafer on dialysis patients paired with medication reconciliation on an intervention unit compared to a control unit.

NCT ID: NCT05521425 Recruiting - Clinical trials for Renal Failure Chronic

Randomized Controlled Trial on 3D Printed Assistive Device for Continuous Ambulatory Peritoneal Dialysis

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

Touch contamination during bag exchange in Continuous Ambulatory Peritoneal Dialysis (CAPD) is a common cause of CAPD-related peritonitis. An innovative 3D-printed assistive device "Helping Hands" was designed to minimize direct touch of tubing during CAPD bag exchange to allow a safer connection process for patients with Chronic Kidney Disease (CKD) to reduce the risk of CAPD-related peritonitis. Through this randomized control, the investigators aimed to evaluate the safety and efficacy of "Helping Hands" in CAPD bag exchange procedure for patients on CAPD therapy.

NCT ID: NCT05418816 Active, not recruiting - Clinical trials for Chronic Kidney Diseases

SelfWrap-Assisted Arteriovenous Fistulas

SW-AVF
Start date: June 14, 2021
Phase: N/A
Study type: Interventional

This is a single-center, prospective, single-arm clinical study to evaluate the feasibility, safety, and performance of VenoStent's SelfWrap® Bioabsorbable Perivascular Wrap on arteriovenous fistulas (AVFs). All participants are chronic kidney disease (CKD) patients already receiving hemodialysis treatments that are referred for creation of a new arteriovenous fistula (AVF).

NCT ID: NCT05381961 Active, not recruiting - Hemodialysis Clinical Trials

Observational Study of BIS in Hemodialysis Patients

Start date: April 4, 2022
Phase:
Study type: Observational

This observational study will evaluate bioimpedance spectroscopy (BIS) measurements from patients undergoing hemodialysis.

NCT ID: NCT05077163 Recruiting - Clinical trials for Renal Failure Chronic

Patients With Acute Renal Failure During Severe COVID-19

IR-EST-POSTCOV
Start date: December 1, 2020
Phase:
Study type: Observational

The occurrence of renal failure during severe forms of COVID-19 is common (20-35% of patients treated in intensive care) and associated with an unfavorable short-term prognosis, but the medium-term renal outcome is not is not known. The aim of the study is to establish the frequency of chronic kidney failure after AKI KDIGO 2 and 3 occurring during severe COVID-19 in intensive care.

NCT ID: NCT04908345 Recruiting - Surgery Clinical Trials

Methadone Anesthesia For Kidney Transplant Receptors

Start date: May 17, 2021
Phase: Phase 3
Study type: Interventional

Intraoperative methadone or fentanyl will be administered to patients submitted to kidney transplant surgery. Postoperative pain, analgesic consumption and side effects will be evaluated

NCT ID: NCT04377243 Not yet recruiting - Clinical trials for Renal Failure Chronic

Immunotherapy of Chronic Kidney Failure

Start date: June 16, 2020
Phase: Phase 2
Study type: Interventional

Kidney failure can result from inflammatory renal disease in the context of autoimmunity because the kidney is targeted by host's immune response against self. There are many causes to this, but abnormal kidney function tests, i.e., BUN and creatinine, can reveal the disease. Oral delivery of kidney cells is ought to produce the immune tolerance - phenomenon is known as oral tolerance. Preliminary studies produced convincing evidence that this hypothesis holds true and has not produced any adverse side effects. Intended open label Phase II aims to confirm these findings.

NCT ID: NCT04204005 Completed - Clinical trials for Renal Failure Chronic

Probiotics and Low Protein Diet in Advanced Chronic Kidney Disease

ProLowCKD
Start date: March 13, 2017
Phase: N/A
Study type: Interventional

Here the investigators will perform a double-blinded randomized placebo-controlled clinical trial to evaluate the synergic effect of low protein diet and prebiotics in reducing the microbial inflammatory uremic toxins.