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STabilization of Atheroma By Lipid-reducing Effect of Drug-Coated Balloon (STABLE-DCB) — STABLE-DCB  

Coronary Artery Disease Clinical Trial

Official title:
Drug-Coated Balloon Angioplasty Facilitates Rapid Reduction in Plaque Lipid Burden in Patients With Multivessel Coronary Artery Disease: A Serial NIRS-IVUS Imaging Study

Clinical Trial Summary

This study aims to investigate whether DCB angioplasty, compared to statin-based medical treatment alone, will lead to more reduction in plaque lipid burden as assessed by near infrared spectroscopy (NIRS) at 6-9 months following the index procedure.

Clinical Trial Description

A large lipid core is the hallmark of coronary plaques at risk of rupture and subsequent atherothrombosis. Although statin-based medical treatment is known to regress and stabilize lipid-rich coronary plaques, it takes time for such beneficial effects to appear. This study aims to investigate whether DCB angioplasty can effectively modify de novo coronary atherosclerotic plaque and lead to reduction in plaque lipid burden as assessed by near infrared spectroscopy (NIRS) at 6-9 months following the index procedure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05438121
Study type Observational
Source Korea University Ansan Hospital
Contact Sunwon Kim, MD, PhD
Phone 82-31-8099-6349
Email sunwon11@hanmail.net
Status Recruiting
Phase
Start date October 13, 2022
Completion date December 31, 2025
View Details
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