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Craniotomy clinical trials

View clinical trials related to Craniotomy.

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NCT ID: NCT01502540 Completed - Pain Clinical Trials

Pain Prevalence After Major Craniotomy

Start date: October 2010
Phase: N/A
Study type: Observational

Craniotomies are generally thought to be less painful than other operations. Indeed recent studies have confirmed that pain is a common problem during the postoperative phase following craniotomy.Pain not only causes discomfort, but it is also associated with other potential adverse events such as increased sympathetic activity and elevated systemic blood pressure. These events in turn may contribute to increased intracranial pressure. Some patients may also develop chronic pain.Potent opioids have been avoided due to its potential to cause respiratory depression and risk of masking pupillary signs. As a result postoperative craniotomy pain controls are usually inadequate. In Siriraj hospital, there are 500-600 craniotomy patients per year. Still there are no definite guidelines for postoperative pain management in these patents due to lack of information about quality of postoperative pain control after craniotomy. Objectives Primary objective : - To study incidence of moderate to severe pain during first 48 hours after craniotomy. Secondary objectives : - To determine risk factors for moderate to severe pain during first 48 hours after craniotomy - To evaluate side effects and complications of postoperative craniotomy pain control - To compare patient's expectation for pain management before and after surgery - To determine patient's satisfaction for postoperative pain management

NCT ID: NCT01474304 Recruiting - Craniotomy Clinical Trials

Intravenous Acetaminophen for Craniotomy Patients

IVAC
Start date: November 2011
Phase: Phase 2
Study type: Interventional

Adding intraoperative IV acetaminophen, in addition to standard analgesics, will decrease opioid requirements over the first 12 hours of postoperative recovery following craniotomy. Opioids exacerbate symptoms of nausea and vomiting. Reducing postoperative opioid use hopefully will reduce incidence of nausea and vomiting in patients after craniotomy.

NCT ID: NCT01408524 Completed - Hypertension Clinical Trials

Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem

Start date: February 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of the antihypertensive drugs in the control of emergence blood pressure after tumor resection craniotomy; compared between labetalol (Avexa) and diltiazem (Herbessor). Also the investigators seek to determine the effective dose of the antihypertensive drugs and their side effects in Thai population.

NCT ID: NCT01282645 Withdrawn - Craniotomy Clinical Trials

Case Series to Evaluate Patient Specific Implants (PSI) in Polyether Ether Ketone (PEEK) Performance After 2 Years

Start date: July 2011
Phase: N/A
Study type: Observational

The primary objective of this retrospective study is to evaluate the percentage of patients with device related adverse events (infection, rejection, dislocation, fracture of the implant) in the first 24 months after implantation.

NCT ID: NCT01256749 Completed - Craniotomy Clinical Trials

A Comparative Study of Global 12 Lead Electroencephalogram to Frontal SedlineTM Electroencephalogram

Start date: December 2010
Phase: N/A
Study type: Observational

The fundamental reason for comparing the ability of the Frontal Sedline TM Electroencephalogram (PSA EEG) to standard Global 12 Lead Electroencephalogram (EEG) for burst suppression detection is to determine if a less expensive, less invasive and possibly more convenient bifrontal EEG monitor can be effective for evaluation of anesthesia-induced intraoperative burst suppression therapy (IBST) for cerebral protection.

NCT ID: NCT00741351 Completed - Anesthesia Clinical Trials

Anesthesiological Strategies in Elective Craniotomy

Neuromorfeo
Start date: December 2007
Phase: Phase 3
Study type: Interventional

This protocol, NeuroMorfeo, aims to assess equivalence between volatile and intravenous anesthetics for neurosurgical procedures.

NCT ID: NCT00658242 Completed - Craniotomy Clinical Trials

Craniofacial Surgery Perioperative Registry

Start date: March 2008
Phase: N/A
Study type: Observational

Craniofacial reconstruction procedures are undertaken in young children to improve appearance, prevent functional disturbances, and enhance psychosocial development. These procedures involve wide scalp dissections and multiple osteotomies and have been associated with significant morbidity. The most commonly seen perioperative complications are associated with the rate and extent of blood loss. This prospective observational registry will be a research tool which will provide a means to evaluate perioperative management of these children at CHOP.

NCT ID: NCT00590499 Completed - Agitation Clinical Trials

Agitation in Post Operative Neurosurgical Patients

Start date: July 2012
Phase: N/A
Study type: Observational

Agitation is a significant clinical issue in anesthesiology and critical care medicine. Several studies have carried out to survey the epidemics of agitation in post-anesthesia care unit and intensive care unit, and results revealed that agitation had an adverse impact on outcomes. To our clinical experience, agitation can occur in postoperative neurosurgical patients, and is often difficult to manage. However, agitation in this subset of patients is poorly evaluated. In present study, adult patients following craniotomy will be enrolled consecutively, and incidence, risk factor and outcome of emergent agitation will be investigated. The results of the study will provide basic data for prevention and treatment of agitation in postoperative neurosurgical patients.