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LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)

COVID-19 Clinical Trial

Official title:
Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) to Evaluate the Safety and Efficacy of Drug Combinations in COVID-19 Patients

Clinical Trial Summary

This master protocol serves as a common reference for the inpatient and outpatient clinical studies that share common elements.

Clinical Trial Description

There are currently two addenda to this master protocol: Addendum 1, Study LDOS-21-001-01, is a Phase 2, randomized, single-blind, placebo-controlled study to evaluate the safety and efficacy of the combination of famotidine and celecoxib as a treatment in moderate-to-severe patients hospitalized for COVID-19. Addendum 2, Study LDOS-21-001-02, is a Phase 2 randomized, placebo-controlled, double-blind study to evaluate the safety and efficacy of the combination of famotidine and celecoxib as a post-exposure prophylaxis (PEP) for newly infected COVID-19 patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05077332
Study type Interventional
Source Leidos Life Sciences
Contact
Status Active, not recruiting
Phase Phase 2
Start date December 29, 2021
Completion date January 2025
View Details
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