Characteristics and Outcome of Patients With COVID-19 in ICUs in South Tyrol

COVID-19 Clinical Trial

Official title:

Characteristics and Outcome of Patients With COVID-19 Associated Respiratory Failure Treated in South Tyrol, Italy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05077319
• Other study ID #: 1
• Status: Completed
• Start date: March 5, 2020
• Est. completion date: October 4, 2021

Study information

• Verified date: October 2021
• Source: Institute of Mountain Emergency Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators retrospectively investigate the epidemiology, clinical characteristics and therapeutic interventions of patients with COVID-19 associated respiratory failure admitted to the intensive care units in South Tyrol, Italy.

Description:

In this observational, retrospective study the epidemiology, characteristics, therapeutic interventions and outcome of patients with COVID-19 associated respiratory failure admitted to the intensive care units in South Tyrol, Italy, are assessed. Data extracted from the medical patients' records include type and duration of respiratory support (high-flow nasal oxygen, non-invasive ventilation, invasive ventilation), need for tracheostomy, vasopressor needs, antibiotic therapy, corticosteroid treatment, laboratory values (interleukin-6, C-reactive protein, procalcitonin, D-dimer, lymphocyte count), lengths of stay in the ICU and mortality.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 550
• Est. completion date: October 4, 2021
• Est. primary completion date: September 20, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• All patients admitted to the intensive care units in South Tyrol due to COVID-19 associated respiratory failure

Exclusion Criteria:

• SARS-CoV-2 patients admitted to the intensive care units in South Tyrol for other pathologies (i.e., not respiratory failure)

Related Conditions & MeSH terms

• Acute Lung Injury
• COVID-19
• Respiratory Distress Syndrome
• Respiratory Distress Syndrome, Newborn

Locations

Country	Name	City	State
Italy	Eurac research	Bolzano

Sponsors (2)

Lead Sponsor	Collaborator
Institute of Mountain Emergency Medicine	Azienda Sanitaria dell'Alto Adige

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality	Mortality (dead/alive) at discharge from the ICU is defined as primary outcome	Through study completion, an average of 1 year