Covid19 Clinical Trial
Official title:
Policy Responses Against the COVID-19 Pandemic in Latin America: Interrupted Series Analyses of Local Governments
Latin America is one of the worst-hit areas from the COVID-19 pandemic worldwide. Policy responses to COVID-19 in Latin America have sought to reduce viral spread, increase the capacity of the health system response, mitigate negative consequences, and strengthen governance. Few studies have examined the effectiveness of COVID-19 policies in Latin America or explored subnational variation in their effectiveness. In this observational study, the investigators will use a two-stage interrupted time series to estimate the effectiveness of nonpharmaceutical interventions in third-tier subnational units on SARS-COV2 transmission and COVID-19 mortality in Latin America. The investigators will estimate the effects in each local government, and then run a random-effects meta-analysis to obtain pooled effects for each intervention (and combinations of) and heterogeneity estimates. Finally, the investigators will explore potential explanations for the heterogeneity at the local level.
Status | Not yet recruiting |
Enrollment | 10000 |
Est. completion date | May 31, 2021 |
Est. primary completion date | May 31, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Country will be eligible if they are (1) Spanish or Portuguese speaking countries in Latin America, (2) availability of open data at the subnational level for any of the outcomes Exclusion Criteria: - None |
Country | Name | City | State |
---|---|---|---|
Chile | Escuela de Salud Pública | Santiago | Región Metropolitana |
Lead Sponsor | Collaborator |
---|---|
University of Chile |
Chile,
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* Note: There are 20 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 7-day moving average of daily confirmed cases of COVID-19/SARS-CoV-2 | Intervention period of up to 30 days (intervention periods lower than 7 days will be considered as a combined set of interventions) | ||
Primary | Time-varying reproductive number of confirmed cases of COVID-19/SARS-CoV-2 | Intervention period of up to 30 days (intervention periods lower than 7 days will be considered as a combined set of interventions) | ||
Primary | 7-day moving average of daily confirmed deaths of COVID-19/SARS-CoV-2 | Intervention period of up to 30 days (intervention periods lower than 7 days will be considered as a combined set of interventions) |
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