Covid19 Clinical Trial
Official title:
Pulmonary Tomographic Findings in COVID-19 and Influenza H1N1 Patients at IMSS Guanajuato
The investigators decided to conduct a longitudinal study that compares the pulmonary tomographic patterns found in patients with viral pneumonia (i.e. influenza H1N1 and SARS-CoV-2) at a regional hospital. The primary aim of this study is to evaluate the association between the radiological CT pattern and the need for invasive mechanical ventilation. A secondary aim is to assess the mortality within the first 28 days of intensive care unit admission.
Status | Recruiting |
Enrollment | 200 |
Est. completion date | April 30, 2022 |
Est. primary completion date | April 30, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Patients with signed informed consent. - Patients with a positive PCR test for SARS-CoV-2 or influenza H1N1 test upon emergency department admission. - Patients with lung CT within 24hrs of specimen collection for PCR test. - Patients with complete 30-day follow-up information. Exclusion Criteria: - Patients who are unwilling to undergo a lung CT. - Negative PCR test for SARS-CoV-2 or influenza H1N1 test upon emergency department admission. - Patients with a tumor or tumor metastasis on the pulmonary CT. - Patients with a previous or de novo autoimmune disease diagnosis. - Patients with a previous or de novo interstitial lung disease. - Pregnancy. Elimination Criteria: - Patients with loss of information on the variables of interest. - Patients without 30-day follow-up information. - Patients who chose to withdraw their participation at any time of the study. |
Country | Name | City | State |
---|---|---|---|
Mexico | Hospital General Regional Leon Imss N0. 58 | León | Guanajuato |
Lead Sponsor | Collaborator |
---|---|
Universidad de Guanajuato | University Medical Center Groningen |
Mexico,
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* Note: There are 13 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Oral intubation | Need for oral intubation within the first 10 days. | 10 days | |
Secondary | Survival | 28-day survival analysis using the Kaplan Meyer and Cox regression models. | 28 days |
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