Preeclampsia-like Syndrome Induced by COVID-19: Is it a Real Public Health Issue in Pregnancy During the Pandemic?

Covid-19 Clinical Trial

Official title:

Evaluation of COVID-19 Incidence in Patients With Preeclampsia During Pandemic

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04443140
• Other study ID #: 70/2020
• Status: Completed
• Start date: March 15, 2020
• Est. completion date: July 10, 2020

Study information

• Verified date: July 2020
• Source: Zeynep Kamil Maternity and Pediatric Research and Training Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

By applying polymerase chain reaction (PCR) test for Covid-19 to preeclampsia patients who applied to our hospital during the Covid-19 pandemic period, we investigated the frequency of Covid-19 related preeclampsia-like syndrome in this patient group.

Description:

The investigators studied the frequency of Covid-19 related preeclampsia-like syndrome by PCR test and lung ultrasound for Covid-19 to preeclampsia patients presenting to the instutution during the Covid-19 pandemic period. The first consecutive 100 preeclampsia patients presented to our hospital during the pandemic will be involved in our study. The primary outcome measure is to detect Covid-19 positivity among the preeclamptic pregnant women..

Recruitment information / eligibility

• Status: Completed
• Enrollment: 131
• Est. completion date: July 10, 2020
• Est. primary completion date: July 1, 2020
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• First consecutive 100 pregnant women presenting with preeclamptic symptoms and signs between March 15, 2020 and June 1, 2020.

Exclusion Criteria:

• The pregnancies with known diagnosis of preeclampsia before Covid-19 pandemic

• Preeclamptic patient without a Covid-19 PCR test result

• Pregnant women who does not want to participate in study or does not want their personal informations to be shared

• Pregnant women less than 18 years old and more than 40 years old are excluded

Related Conditions & MeSH terms

• Covid-19
• Pre-Eclampsia
• Preeclampsia
• Pregnancy Related

Intervention

Diagnostic Test:
• PCR, lung ultrasound
PCR for Covid-19

Locations

Country	Name	City	State
Turkey	Zeynep Kamil Maternity and Childrens Training and Research Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Zeynep Kamil Maternity and Pediatric Research and Training Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (1)

Mendoza M, Garcia-Ruiz I, Maiz N, Rodo C, Garcia-Manau P, Serrano B, Lopez-Martinez RM, Balcells J, Fernandez-Hidalgo N, Carreras E, Suy A. Pre-eclampsia-like syndrome induced by severe COVID-19: a prospective observational study. BJOG. 2020 Jun 1. doi: 1 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PCR positivity	To detect Covid-19 PCR test positivity among preeclamptic pregnant women	3 months