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NCT ID: NCT05944757 Enrolling by invitation - PRP Clinical Trials

Compare of PRP Autologous Serum and Autologous Serum by Intrastromal Injection in Different Eye Disease Conditions

prp
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Platelet-rich plasma (PRP) is an autologous blood product rich in proteins and growth factors. Its application has been the subject of many studies in the field of ophthalmology to stimulate tissue healing and regeneration. Due to its anatomical features (lack of blood vessels), the cornea is among the most susceptible to damage structures of the eye. Therefore, the study of the impact of various regenerative therapies (autologous blood products, serums, ) on corneal lesions is important not only scientifically, but also practically for ophthalmologist. Numerous reports described the healing effect of PRP on corneal lesions.

NCT ID: NCT05156151 Enrolling by invitation - Stromal Keratitis Clinical Trials

Stromal Lenticule Implantation for Management of Herpetic Stromal Keratitis

Relex-Smile
Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is the evaluation of corneal transparency and improvement of visual acuity in patients with herpetic stromal keratitis.

NCT ID: NCT05115058 Enrolling by invitation - Presbyopia Clinical Trials

A New Successful Approach for Emmetropic Presbyopic Patients Using Intrastromal Pocket With Smile Module

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Presbyopia is physiological insufficiency of accommodation associated with the aging of the eye that results in progressively worsening ability to focus clearly on close objects.Though presbyopia is a normal change in our eyes as we age, it often is a significant and emotional event because it's a sign of aging that's impossible to ignore and difficult to hide. This defect is usually corrected by using glasses with bifocal power of suitable focal lengths. But some patients don't want to use glasses for correction. In our study purpose is to show that near vision improves and patient satisfaction increases by preparing an intrastromal pocket for emmetropic patients with near vision problems using the SMILE module.

NCT ID: NCT04848740 Enrolling by invitation - Clinical trials for Progressive Disease of Corneae

Human Fresh Corneal Lenticule Implantation Criteria in Progressive Corneal Disease Using Relex-Smile

Relex-Smile
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Stroma is a fibrous, tough, transparent and the thickest layer of the corneae. The stroma is composed of organised collagen, which maintains transparency. Keratocytes are located between the lamella collagen fibers and secrete an extracellular matrix, which includes collagen, proteoglycan, crystalline proteins to maintain corneal transparency.

NCT ID: NCT04793893 Enrolling by invitation - Refractive Errors Clinical Trials

Treatment of Residual Hypermetropic Refraction on Young Patients After LASIK Using Human Fresh Corneal Lenticule Implantation With ReLEX Smile Surgery

Relex-Smile
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

LASIK (laser-assisted in situ keratomileusis) is a type of refractive surgery for correction of myopia, hyperopia and astigmatism. Yet approximately 30% of operated patients have symptoms like glare, halos, dry eyes and especially residual hypermetrop refractive errors. Residual hypermetrop refractive errors are difficult to treat surgically, the current treatment is Refractive Lens Implantation - risks are similar to those of cataract surgery (endophthalmitis, loss of accommodation, etc.)

NCT ID: NCT04712318 Enrolling by invitation - Myopia Clinical Trials

Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Successful treatment of residual refraction 6 months after IOL Implantation with Relex-Smile.

NCT ID: NCT04693663 Enrolling by invitation - Myopia Clinical Trials

Treatment of Residual Myopic Refraction After 6 Months on Pseudophakic Patients Using Relex-Smile

Relex-Smile
Start date: June 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to assess visual and refractive outcomes after laser vision correction (LVC) - ReLex Smile to correct residual myopic refraction after 6 months of pseudophakic (IOL) implantation. Before SMILE YAG-Laser capsulotomy should be performed on all patients, regardless of posterior capsule ossification, in pseudophakic patients with residual refraction. When the YAG Laser is applied after the SMILE, there will be a diopter change.

NCT ID: NCT04642729 Enrolling by invitation - Clinical trials for Macular Corneal Dystrophy

Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to examine the effect of fresh corneal lenticule implantation as allogenic graft taken from myopic patients to implanted in patients with macular corneal dystrophy using Visumax Femtosecond Laser Smile module surgery.

NCT ID: NCT04591587 Enrolling by invitation - Keratoconus Clinical Trials

Corneal Lenticule Implantation in Keratoconus Disease With Relex Smile Surgery

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

CORNEAL LENTICULE IMPLANTATION IN KERATOCONUS DISEASE WITH RELEX SMILE SURGERY