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NCT ID: NCT04939571 Recruiting - Clinical trials for Retinopathy of Prematurity

European Disease Registry on Retinopathy of Prematurity (ROP)

EU-ROP
Start date: August 6, 2021
Phase:
Study type: Observational [Patient Registry]

The EU-ROP registry is a European wide multicenter non-interventional observational registry study intended to run open-ended in as many countries as possible including infants treated for retinopathy of prematurity irrespective of the used treatment modality. The registry is strictly observational; only clinical routine data is collected, no study-specific examinations or interventions are to be performed. The aim of the EU-ROP registry is to collect information on as many patients as possible treated for ROP in Europe. Both the number of study centers as well as the number of patients to be included into the registry are not limited. The primary objective is to describe the typical clinical features of infants with severe ROP, variations in phenotype, and the clinical progression of the disease over time (natural history) in different European countries as well as to study treatment patterns, follow-up patterns, as well as long-term outcomes.

NCT ID: NCT04913623 Recruiting - Clinical trials for Arthroplasty Complications

Correlation of Intramedullary Pressure and Systemic Inflammatory Parameters in Cemented Femoral Stem

Start date: March 23, 2021
Phase:
Study type: Observational

The cemented femoral stem have impact on increase on systemic parameters. Evaluation of the level of histamine, C-reactive protein (CRP) and leukocytes formula, IL1b, TNF alpha, IL6 and the reflection of changes of these parameters in the intra-operative course of hip replacement.

NCT ID: NCT03921567 Recruiting - Clinical trials for Analgesic Drug Dependence

Intravenous Lidocaine for Perioperative and Postoperative Analgesia

Start date: April 15, 2019
Phase: Phase 4
Study type: Interventional

Postoperative pain continues to be untreated despite the application of multimodal analgesia, medication and new analgesic techniques. Traditional opioid pain treatment has many side effects, while invasive methods, such as epidural catheter, have high costs and difficulties during application. Lidocaine is a local anesthetic and its administration with intravenous routes has analgesic, antihyperalgic and antiinflammatory action. It increases the motility of the intestine and has antiemetic properties. The advantage of this method is the low cost of the preparation and its easy application. The intravenous administration of lidocaine for postoperative analgesia is recently used and not sufficiently researched technique .

NCT ID: NCT02874963 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis

Start date: November 2015
Phase: N/A
Study type: Interventional

This intervention study is designed to evaluate the effects of non-surgical procedure in addition to surgical procedure on systemic inflammation and glycemic control in with type 2 diabetes mellitus patients with periodontitis in comparison with non-diabetic periodontic patients.