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NCT ID: NCT05888337 Terminated - Myopia Clinical Trials

Comparison of Contoura Vision Outcomes Programmed Using the Manifest Refraction Verses Using Phorcides Planning Software in Patients With Oblique Astigmatism

Start date: June 20, 2023
Phase:
Study type: Observational

The objective is to compare the percentage of monocular UDVA -0.1 logMAR (20/16) outcomes for each planning strategy (Phorcides and manifest refraction) at the 3-month post operative visit.

NCT ID: NCT05878652 Terminated - ACL Injury Clinical Trials

Playmaker 3D Printed Knee Extender

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to explore the development of, and patient outcomes associated with, the use of individually printed knee extender in conjunction with a video-based home pre-habilitation program for patients who have suffered an ACL rupture before surgery.

NCT ID: NCT05877404 Terminated - Endometrial Cancer Clinical Trials

Practice Patterns Among Gynecologic Oncologists on Tumor Genetic Testing in Endometrial Cancer

Start date: August 15, 2023
Phase:
Study type: Observational

In order to formulate strategies to improve adherence to best practice guidelines, as well as utilization of novel therapies, investigators must understand current practice patterns surrounding tumor genetic testing in endometrial cancer. The aim is to survey a representative sample of gynecologic oncologists who belong to the society of gynecologic oncology, via an email survey, to better understand current practices surrounding tumor genetic testing as well as determine if there have been any changes to practice since the publication of recent trials on the use of immune-checkpoint inhibitors in endometrial cancer.

NCT ID: NCT05877066 Terminated - Clinical trials for Dupuytren's Contracture

Real-World Data Study to Understand Participant Treatment Outcomes for Dupuytren's Contracture

GRASP-DC
Start date: June 14, 2023
Phase:
Study type: Observational [Patient Registry]

This is an observational study, meaning participants will not receive any investigational treatment as part of this study. Researchers will collect real-world data (RWD), based on usual care, to gain a more in-depth knowledge of the natural history and the treatment outcomes of Dupuytren's Contracture (DC) to evaluate the management of DC.

NCT ID: NCT05873595 Terminated - Peyronie's Disease Clinical Trials

Real-World Data Study to Understand Effectiveness of Treatments in Peyronie's Disease

CURVE-PD
Start date: June 20, 2023
Phase:
Study type: Observational [Patient Registry]

This is an observational study, meaning participants will not receive any investigational treatment as part of this study. Researchers will collect real-world data (RWD) to gain a more in-depth knowledge of the treatment of Peyronie's Disease (PD) to evaluate the management of PD.

NCT ID: NCT05864391 Terminated - Steatohepatitis Clinical Trials

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD7503 in Participants With Suspected NASH.

Start date: March 31, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the safety, tolerability, and PK (measurement of drug activity in the body over time) of AZD7503 injected subcutaneously, and compared to placebo, in participants with suspected NASH, a type of liver disease.

NCT ID: NCT05859087 Terminated - Chronic Disease Clinical Trials

Family Planning Counseling for Women With Chronic Medical Conditions in an Inpatient Setting

Start date: February 26, 2018
Phase: N/A
Study type: Interventional

Women with chronic medical conditions have been found in multiple studies to use birth control less often compared to women without chronic medical conditions. The investigators hypothesized that approaching women with chronic medical conditions who were admitted to the hospital and having a bedside conversation about pregnancy intention and counseling regarding birth control usage along with offering to start birth control before discharge would increase the use of birth control in this population. As a separate intervention, the investigators hypothesized that having a brief conversation with the participants and then giving them a flyer that recommended talking with their doctor about birth control could also increase the use of birth control in this population.

NCT ID: NCT05851430 Terminated - Soft Tissue Lesion Clinical Trials

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

PROPEL
Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational registry is to assess the use and performance of Galvanize PEF technology in a real-world setting. The main questions it aims to answer are: - PEF utilization and performance - Monitor safety outcomes and inform future generation devices. Participants will undergo the PEF procedure and be followed per institutional standard of care.

NCT ID: NCT05848219 Terminated - Metastatic Melanoma Clinical Trials

Healthcare Resource Utilization and Costs in Metastatic Melanoma Patients Initiated Dabrafenib + Trametinib and Encorafenib + Binimetinib

Start date: October 16, 2021
Phase:
Study type: Observational

This was a retrospective cohort study using the MarketScan health care administrative claim databases: Truven Health Analytics' MarketScan Commercial Claims and Encounters; MarketScan Medicare Supplement and Coordination of Benefit. We conducted this analysis using the most recent available data from the MarketScan database at the time of analysis, which was 01 June 2018 to 31 December 2020. We initiated this analysis from 01 June 2018 as encorafenib + binimetinib (enco/bini) was approved for patients with unresectable or metastatic melanoma with BRAF mutation at this time.

NCT ID: NCT05835011 Terminated - Clinical trials for Myelodysplastic Syndromes

A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

Start date: July 14, 2023
Phase: Phase 2
Study type: Interventional

The primary purpose of the study is to evaluate the preliminary safety and efficacy of oral decitabine/cedazuridine in combination with magrolimab.