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NCT ID: NCT05206058 Completed - Neutrophil Clinical Trials

To Exam the Effects of Phyllanthus Niruri Extracts on Human Neutrophils

Start date: January 1, 2022
Phase:
Study type: Observational

To exam the effects of Phyllanthus niruri extracts(corilagin, phyllanthin and brevifolin) on human neutrophils

NCT ID: NCT05201924 Completed - Sleep Clinical Trials

Bedtime Routines and Children's Health

Start date: January 31, 2021
Phase: N/A
Study type: Interventional

In Taiwan, the prevalence of sleep problems, myopia, and dental caries in school-age children is high. Little is known regarding the implementation of oral and vision health outcomes around bedtime. A bedtime routine intervention was conducted to improve children's oral, vision and sleep health.

NCT ID: NCT05201040 Completed - Knee Osteoarthritis Clinical Trials

Evaluate the Safety and Effectiveness of Mannitol-combined Hyaluronan Supplement in the Treatment of Knee OA

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of JETKNEE Synovial Fluid Supplement for alleviating pain of knee osteoarthritis (OA).

NCT ID: NCT05199623 Completed - Traumatic Anosmia Clinical Trials

The Effect of Chinese Herbal Medicine as an Adjuvant Therapy in the Treatment of Traumatic Anosmia

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Objective: To investigate the effect of Chinese herbal medicine (CHM) as an adjuvant therapy in the treatment of traumatic anosmia. Methods: Patients with a clear history of loss of smell after head injury, and whose phenyl ethyl alcohol (PEA) odor detection threshold remained -1 after treatment with steroid, zinc, and olfactory training (OT) for one month, were included in this study between September of 2018 and November of 2020. They were randomly divided into 2 groups, with patients in the CHM group taking CHM (tailored Guizhi decoction) and performing OT, and those in the OT group receiving OT only for 6 months. After 3 months' and 6 months' treatment, the olfactory function was evaluated by both the PEA threshold test and the traditional Chinese version of the University of Pennsylvania Smell Identification Test (UPSIT-TC). Magnetic resonance imaging was performed to measure the volume of olfactory bulbs after 6 months' treatment.

NCT ID: NCT05197153 Completed - COVID-19 Vaccine Clinical Trials

A Study to Evaluate the Safety and Immunogenicity of Booster With AZD1222, mRNA-1273, or MVC-COV1901 Against COVID-19

Start date: January 22, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, and immunogenicity of booster dose of vaccine in participants who are generally healthy or with stable pre-existing health conditions. Study details include: - The study duration per participant will be approximately 209 days (28 days screening, 1 day vaccination, and 180 days follow-up). - The treatment will include 1 booster dose only. - The visit frequency will be 6 on-site visits and 1 phone visit.

NCT ID: NCT05195736 Completed - COVID-19 Clinical Trials

Predicting COVID-19 Patients' Clinical Outcomes Using ICU Mobility Scale and MRC Sum Score

Start date: September 16, 2021
Phase:
Study type: Observational

The investigators hypothesize that early mobility condition and muscle power may be the predictive factors for Coronavirus disease 2019(COVID-19) patients' activity prognosis and hospitalization days. To prove our hypothesis, the investigators proposed a retrospective cohort study to see if ICU mobility scale(ICUMS) and Medical Research Council Sum Score(MRCSS) can predicted the patients' Barthel index after discharge and hospitalization days.

NCT ID: NCT05193773 Completed - Intervention Clinical Trials

Effects of a Multifactorial Intervention to Reduce Physical Restraints for Care Providers in Nursing Homes

Start date: September 7, 2015
Phase: N/A
Study type: Interventional

Scholars from around the world have been strongly advocating restraint-free care in long-term care institutions. Therefore, the aim of this study was to evaluate the effects of a multifactorial intervention to reduce physical restraints for care providers in nursing homes.

NCT ID: NCT05191732 Completed - Clinical trials for Anterior Cruciate Ligament Reconstruction

Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction

Start date: August 3, 2018
Phase: N/A
Study type: Interventional

Anterior cruciate ligament (ACL) is an important stabilizer of knee during daily activity and exercise. The ruptured ACL need to be reconstructed by a new tendon graft which passed the bone tunnel and joint during operation. How to enhance the tendon graft to bone tunnel healing is critical important to prevent recurrent ligament laxity, avoid secondary osteoarthritis, and achieve early return to sports and work. Platelet Rich Plasma (PRP),harvest from peripheral blood, is rich in multiple growth factors(i.e. VEGF, PDGD, TGFB, IGF, EGF) which help the injured tissue regeneration. Bone marrow stem cell has been demonstrated to enhance the injured tissue repair both in vitro and in vivo study. However, there is no prospective study in comparing the PRP and BMC to enhance interfacial healing between graft and bone tunnel in ACL reconstruction. Investigators hypothesize that the combination of PRP and BMC has synergetic effect in interfacial healing in ACL reconstruction. Aim of this study: To investigate the result of clinical functional scoring, MRI, and biomechanical study between PRP augmentation, PRP+BMC augmentation and traditional ACL reconstruction.

NCT ID: NCT05191511 Completed - Far- Infrared Burn Clinical Trials

Assessment of Safety Distance of Far-Infrared Therapeutic Device to Human Skin

Start date: March 4, 2019
Phase:
Study type: Observational

Abstract The equipment "infrared therapeutic device" is widely used in various medical institutions in Taiwan. The infrared therapeutic device improves the blood circulation, relieves muscle stiffness and pain by the heat energy radiated by the infrared light, and has a significant relief effect on patients with joint pain, muscle soreness, and back discomfort. However, the principle of the infrared therapeutic device is thermal energy, and there is no complete literature on the parameters such as treatment intensity and time and the full distance. In addition, the literature on the damage that can be caused is not based on clinical evidence, and there is no standardization study on the use of equipment, so it is hoped that this test will explore the safety distance of infrared therapeutic devices. The project is expected to recruit 50 people from 20 years old to 75 years old in the Chinese Medicine Clinic of Tainan Hospital of the Ministry of Health and Welfare, which is included in the diagnosis of osteoarthritis, degenerative arthritis, osteoporosis and other related Chinese medicine clinics. In patients with diseases, the main complaint must include patients with lower back pain and back pain. Subjects should exclude diseases that may be affected by chemoradiotherapy, cardiovascular disease, anemia, hypertension, etc., and exclude dermatitis, skin irritation, and erythema. Skin diseases such as lupus. The test site is the TCM clinic of Tainan Hospital of the Ministry of Health and Welfare. The air conditioner is fixed at a constant temperature of 28 degrees. The output power is calculated by the wattage meter, and the distance and temperature of the infrared lamp are measured. Finally, the appropriate temperature and distance of the infrared lamp to the human skin are estimated through calculation. Keywords: Infrared, Far- infrared, Burn

NCT ID: NCT05191056 Completed - Aging Clinical Trials

Anti-aging and Anti-oxidant Efficacy Evaluation of the MelaGene

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

The primary purpose of the present study is to evaluate the effects of MelaGene on anti-aging and anti-oxidant.