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NCT ID: NCT06425302 Not yet recruiting - Clinical trials for Lymphoma, Follicular

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

GOLSEEK-2
Start date: August 3, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of golcadomide in combination with rituximab in participants with newly diagnosed advanced stage Follicular Lymphoma (FL).

NCT ID: NCT06416943 Not yet recruiting - Cancer Clinical Trials

3D Port-A Catheter Model for New Staff

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to develop a highly realistic 3D-printed Port-A catheter upper body model to enhance the effectiveness of training new nursing staff in Port-A catheter placement and care skills.

NCT ID: NCT06413524 Not yet recruiting - COPD Clinical Trials

The Effects of Different Vibration Exercises on COPD Patients

Start date: May 21, 2024
Phase: N/A
Study type: Interventional

Pulmonary rehabilitation is effective in improving exercise tolerance, dyspnea, and fatigue in patients with COPD, and exercise training is an important component of pulmonary rehabilitation. Vibration training can be used as a supplement or alternative to traditional exercise and is a short, safe rehabilitation training. COPD patients will be recruited and randomly assigned to the control group, whole-body vibration training group, or local vibration training group. The study aims to confirm the rehabilitative benefits of enhancing lower limb muscle strength, exercise endurance, and the quality of life related to COPD in patients.

NCT ID: NCT06412627 Not yet recruiting - Dry Mouth Clinical Trials

The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube

Start date: May 2024
Phase: N/A
Study type: Interventional

This is an experimental study aimed at exploring the effectiveness of using 4°C frozen gauze with normal saline for relieving dry mouth and thirst in patients with endotracheal tubes.

NCT ID: NCT06412133 Not yet recruiting - Breast Cancer Clinical Trials

Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients

Start date: September 17, 2024
Phase: N/A
Study type: Interventional

This study examines the impact of phototherapy intervention on anxiety, stress, and body image among breast cancer patients. Participants engaged in a five-week, one-on-one session series, utilizing a pre-post-test design with parallel groups. Quantitative data were collected using the Depression Anxiety Stress Scales (DASS-21) and the Body Image Scale. In addition to quantitative measures, in-depth individual interviews were conducted to gather qualitative data. The combined data were then analysed to assess the effectiveness of the intervention.

NCT ID: NCT06409143 Not yet recruiting - Stroke Clinical Trials

High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Upper limb hemiparesis is the most common sequelae in patients, severely impacting their independence and quality of life. Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct current or alternating current to change the excitability of the cerebral cortex. It can induces long-term potentiation-like or long-term depression-like effects, thereby modulating the cortical excitability. In recent years, researchers have developed high-definition (HD) devices, which integrate high definition ring electrode configurations and incorporate direct current with theta burst stimulation waveforms. Diverging from traditional transcranial direct current stimulation (tDCS), which applies weak currents (0.5-2 mA) through two large sponge electrodes (25~35 cm^2) externally to the scalp for widespread non-specific cortical stimulation, HD-tES employs an array of small-area electrodes (1 cm^2) to control current distribution over localized cortical regions, thereby enhancing spatial accuracy. However, there is a lack of studies validating the optimal waveform for HD-tES, as well as clinical evidence in subacute stroke populations. The optimal unilateral versus bilateral stimulation modes and their neurological mechanisms for stroke rehabilitation also remain uncertain.

NCT ID: NCT06401954 Not yet recruiting - Flexible Flatfoot Clinical Trials

High-Intensity Focused Electromagnetic Therapy Combined With Foot Core Training for Pronated Foot

Start date: May 15, 2024
Phase: N/A
Study type: Interventional

The objective of this trial is to assess the effects of high-intensity focused electromagnetic therapy combined with foot core training targeting the intrinsic foot muscles on plantar load, static foot posture, intrinsic foot muscle morphology and intrinsic foot muscle activation in individuals with pronated foot. The main questions it aims to answer are: Question 1: To compare changes in plantar load following interventions of high-intensity focused electromagnetic therapy combined with foot core training, high-intensity focused electromagnetic therapy alone, and sham high-intensity focused electromagnetic therapy combined with foot core training. Question 2: To compare changes in static foot posture, intrinsic foot muscle morphology, and intrinsic foot muscle activation following interventions of high-intensity focused electromagnetic therapy combined with foot core training, high-intensity focused electromagnetic therapy alone, and sham high-intensity focused electromagnetic therapy combined with foot core training. Question 3: To assess the effects of each intervention on plantar load, static foot posture, intrinsic foot muscle morphology, and intrinsic foot muscle activation in individuals with pronated foot. Participants will undergo stimulation of their intrinsic foot muscles through high-intensity focused electromagnetic therapy, and they will also be required to isometrically contract their intrinsic foot muscles during the designated exercise program. Researchers will assess the effects of high-intensity focused electromagnetic therapy combined with foot core training by evaluating plantar load during walking, static foot posture, intrinsic foot muscle morphology and intrinsic foot muscle activation during walking.

NCT ID: NCT06398899 Not yet recruiting - Clinical trials for Head and Neck Neoplasms

Sugammadex v.s. Neostigmine/Glycopyrrolate

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of study is to clarify the role of sugammadex in head and neck surgery patients with a prior history of urinary retention, benign prostatic hypertrophy, or a history of prostate cancer, to prevent postoperative urinary retention. The main question it aims to answer are: - Anticholinergic agent interferes the postoperative urination - Sugammadex does not interfere postoperative urination Sugammadex can be recommended for these patients with high risk in postoperative urinary retention in the future.

NCT ID: NCT06397079 Not yet recruiting - Oral Hygiene Clinical Trials

Oral Care Program for Residients in Long-term Care Facility

Start date: May 10, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of an oral care program on the oral hygiene for residents in long-term care facility.

NCT ID: NCT06393075 Not yet recruiting - Clinical trials for Arthroplasty, Knee Replacement

The Effectiveness of Combined Care for Knee Replacement Patients

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effectiveness of combined care guidance and general care guidance on pain scores, anxiety levels and joint mobility in patients undergoing total artificial knee replacement. The main questions it aims to answer are: - Does combined care coaching reduce patient pain scores and anxiety levels after surgery? - Does combined care guidance improve knee joint mobility after surgery? Researchers will compare combined care guidance and general care to see if combined care guidance reduces patients' pain scores and anxiety levels after surgery, and improves knee joint mobility after surgery. Participants will: - Watch pain and rehabilitation exercise guidance videos before surgery and learn how to use a walker. - Complete questionnaires before surgery, 24 hours, 48 hours, 72 hours and three months after surgery. - Questionnaire records pain level, anxiety level and joint mobility.