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NCT ID: NCT05136144 Active, not recruiting - Clinical trials for Seborrheic Keratosis

Adaptive Design Study for Safety and Efficacy of Treatment Regimens With SM-020 in Subjects With Seborrheic Keratosis

Start date: October 19, 2021
Phase: Phase 2
Study type: Interventional

This is a first-in-humans adaptive design open label trial to explore the safety and efficacy of SM-020. Multiple dosing cohorts will be enrolled. The first cohort will have a two-week treatment period of twice daily applications followed by a four-week follow-up period. Based on the results at any time from the first and subsequent cohorts, additional cohorts will explore different dosing regimens.

NCT ID: NCT04937920 Completed - Tinea Versicolor Clinical Trials

A Trial to Evaluate the Safety and Antimicrobial Efficacy of DBI-002 Probiotic in Adults With Tinea Versicolor

Start date: March 16, 2021
Phase: Phase 2
Study type: Interventional

A Randomized, Double-Blinded, Aqueous Gel-Controlled Dose Escalating Trial to Study the Safety and Antimicrobial Efficacy of DBI-002 Probiotic vs. Aqueous Gel and Vehicle Gel vs. Aqueous Gel in Adults with Tinea Versicolor (DBI-202).

NCT ID: NCT04936087 Completed - Wheelchair Users Clinical Trials

Effects of the WHO 8-step Wheelchair Service Delivery Process on Wheelchair Users in El Salvador: a Cohort Study

WUV
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

The objective of this study was to test the hypotheses that wheelchair-related health, wheelchair skills, wheelchair use, poverty probability, and quality of life would improve; and that the number of wheelchair repairs required, adverse events, caregiver burden and the level of assistance provided would decrease after the delivery of manual wheelchairs following the World Health Organization (WHO) 8-step service-delivery process. This was a longitudinal, within-subject study design including 247 manual wheelchair users in El Salvador. The intervention consisted of the WHO 8-step process as well as maintenance reminders. Outcome assessments on wheelchair-related health, wheelchair skills, wheelchair repairs required, adverse events, caregiver burden and the level of assistance, poverty probability, and quality of life were performed via structured interviews at the initial assessment, at wheelchair delivery, and at 3- and 6-month follow-up. Wheelchair use was measured with dataloggers at assessment, delivery and 3-month follow-up.

NCT ID: NCT04711213 Completed - Clinical trials for Cataract in Inflammatory Ocular Disorders

A Clinical Study to Assess the Efficacy and Safety of SED80 for Use in Cataract Surgery

Start date: September 14, 2020
Phase: Phase 2
Study type: Interventional

Patients at least 40 years of age who are undergoing cataract surgery will be randomized to receive treatment with one of four groups of dexamethasone ophthalmic suspension or placebo eye drops to determine if the drops decrease inflammation and pain inside the eye and are safe after cataract surgery.

NCT ID: NCT04684485 Recruiting - Dermatitis, Atopic Clinical Trials

To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis

SOLARES-AD-1
Start date: July 30, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase II, randomized, double-blind, placebo-controlled study in subjects with moderate to severe atopic dermatitis.

NCT ID: NCT04566666 Recruiting - Clinical trials for Moderate to Severe Plaque Psoriasis

To Assess the Effect of SCD-044 Treatment on Moderate to Severe Plaque Psoriasis

SOLARES-PsO-1
Start date: March 26, 2021
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled study in subjects with moderate to severe plaque psoriasis.

NCT ID: NCT04332640 Completed - Cataract Clinical Trials

Clinical Evaluation of the Next Generation Phaco System

ALPINE
Start date: September 28, 2020
Phase: N/A
Study type: Interventional

This study is a prospective, open-label clinical study of the VERITAS Vision System. The study will be conducted at up to three sites, with minimum 55 eyes and up to 150 eyes to be treated. The investigator or designee will perform the cataract surgery with the VERITAS Vision System on the subjects. The data from the system log files, the questionnaire, the operative report and other medical records will be used to assess the clinical utilization of the VERITAS Vision System.

NCT ID: NCT04330001 Completed - Presbyopia Clinical Trials

Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).

NCT ID: NCT04143919 Completed - Heart Failure Clinical Trials

Heart Failure IDentification in a High Risk Cardiovascular OutpatiEnt Population (HIDE)

HIDE
Start date: January 31, 2020
Phase: N/A
Study type: Interventional

This is a pilot, multicenter, real-world, single-visit, low risk, phase IV interventional study to efficiently identify new cases of heart failure (HF) Stage C in subjects who are at risk of cardiovascular (CV) disease in high-volume ambulatory primary care settings in 3 countries in Central America.

NCT ID: NCT03859908 Terminated - Clinical trials for Surgical Site Infection

Comparison of Two Preoperative Antiseptic Solutions Alcohol Based in Abdominal Elective Surgeries

Start date: April 5, 2019
Phase: Phase 4
Study type: Interventional

Pragmatic randomized clinical trial comparing Iodine Povacrylex based on alcohol to Chlorhexidine also based on alcohol in efficacy and security to diminish frequency of surgical site infections in major abdominal elective clean contaminated wounds. Will be held in a third level university, high volume national public hospital in San Salvador, El Salvador.