Clinical Trials Logo

Filter by:
NCT ID: NCT04941131 Not yet recruiting - COVID-19 Clinical Trials

The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients

Start date: July 2021
Phase: Phase 4
Study type: Interventional

Existing evidence confirmed that saliva and oral cavity to be a reservoir for SARS-CoV-2. In dental clinic aerosol-producing-procedures pose a significant risk for transmission of the infection . It is very important to minimize the risk of transmission in dental office reducing the load of SARS-CoV-2 in saliva if possible, in suspect or conformed cases. Preprocedural mouth rises have been used widely to minimize the number of oral microorganisms. Multiple studies confirmed the efficacy of those mouth rinses in reducing the possibility of transmission of SARS-CoV-2 infection .

NCT ID: NCT04716439 Not yet recruiting - Spine Surgery Clinical Trials

Effect of TIVA With Magnesium Sulfate on IONM in Patients Undergoing Spine Surgery

Start date: February 2021
Phase:
Study type: Observational [Patient Registry]

Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression. This randomized placebo-controlled, double-blind study was designed to evaluate the effect of magnesium sulfate on the total anesthetic and analgesic consumption using the clinical parameters in addition to the effect on IONM reading.

NCT ID: NCT04674072 Not yet recruiting - Clinical trials for Quadriceps Muscle Atrophy

The Effect of the Reverse Nordic Curl Exercise on Quadriceps Femoris Muscles Injury Rate Among Soccer Players

Start date: January 16, 2021
Phase: N/A
Study type: Interventional

The reverse Nordic curl is a body-weight exercise which mainly works the quadriceps and hip flexors. It has a large eccentric component, meaning the muscles are working whilst lengthening. The purpose of this study is to investigate the effect of the reverse Nordic curl exercise on Quadriceps femoris muscles injuries among soccer players. It hypothesized that reverse Nordic curl exercise has a beneficial effect in terms of Quadriceps femoris muscles injury prevention.

NCT ID: NCT04673903 Not yet recruiting - Groin Injuries Clinical Trials

The Effect of the Copenhagen Adduction Exercise on Groin Injuries Rate Among Soccer Players.

Start date: January 16, 2021
Phase: N/A
Study type: Interventional

The effect of the Copenhagen Adduction Exercise on groin injuries rate among soccer players The Copenhagen adduction exercise is a body-weight exercise which mainly works the groin and hip Adductors. It has a large eccentric component, meaning the muscles are working whilst lengthening. The purpose of this study is to investigate the effect of the Copenhagen adduction exercise on groin injuries among soccer players. It hypothesized that Copenhagen adduction exercise has a beneficial effect in terms of groin injury prevention.

NCT ID: NCT04673097 Not yet recruiting - White Spot Lesion Clinical Trials

Performance of Different Resin Infiltration Materials on White Spot Lesions: Clinical and Laboratory Assessments

Start date: December 19, 2020
Phase: N/A
Study type: Interventional

The study is a clinical controlled trial. Ethical approval will be obtained from Imam Abdulrahman bin Faisal University, Dammam. The study participants will be recruited from the dental hospital and conducted between November 2020 to November 2020. This will be a single-center, randomized, single blinded with a 1:1:1 allocation ratio for the application of Icon® resin infiltration, MI Paste Plus and both treatments

NCT ID: NCT04666935 Not yet recruiting - Sport Injury Clinical Trials

The Effect of the Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Exercises Reducing Injuries Rate Among Athletes.

Start date: January 16, 2021
Phase: N/A
Study type: Interventional

The Oslo Sports Trauma Research Center (OSTRC) was established in May 2000 at the Norwegian School of Sport Sciences.The OSTRC aims to prevent injuries and other health problems related to sports. The majority of the research conducted at OSTRC involves elite sports. The purpose of this study is to investigate the effect of the Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Program in reducing injuries among athletes. Hypothesis: that Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Program has a beneficial effect in terms of injury prevention. The purpose of this study is to investigate the effect of the Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Program in reducing injuries among athletes.

NCT ID: NCT04554589 Not yet recruiting - Effect of Drugs Clinical Trials

The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.

Start date: September 14, 2020
Phase: Phase 1
Study type: Interventional

Tracheostomized patients in the ICU can have excessive tracheal secretions due to various causes as hyperactive airway, irritation of the mucus producing cells and inhibition of the ciliary functions. Excessive secretions will necessitate frequent suctions which carries the risk of tracheostomy tube obstruction if not managed properly. Excessive tracheal secretions may prolong the ICU stay, increase the nurses workload and increase patients morbidity and mortality. This clinical trial hypothesizes that the use of glycopyrrolate may decrease the tracheal secretions and hence avoid such complications.

NCT ID: NCT04520880 Not yet recruiting - Clinical trials for Hospitalized Patients

Antibodies Responses to COVID-19 Infection in Hospitalized Patients

No-SARS
Start date: August 2020
Phase:
Study type: Observational

1.5. Why this clinical study? The prevalence of seropositivity following SARS-CoV 2 infection might have its own potential benefits in terms of predicting the end of pandemic and the validity of herd immunity. It is not clear if SARS-CoV 2 infection would have a long-lasting antibody-mediated immunity, and if the antibodies' persistence is dependent on disease severity.depends on the severity of illness. If evidence is provided about the persistence of antibodies that is reflective of the protective immune response, serodiagnosis will be an important tool to identify individuals with various risk for infection, and those who are in need of receiving the forthcoming vaccines. The here proposed prospective clinical study will test the prevalence of seropositivity following SARS-CoV 2 infection in critically ill patients compared to those who do not require intensive care unit (ICU) admission or invasive ventilation with respect to the IgM and IgG levels.

NCT ID: NCT04377802 Not yet recruiting - COVID 19 Clinical Trials

Safe Return to Regular Clinical Operation After COVID-19 Pandemic

Start date: May 17, 2020
Phase: N/A
Study type: Interventional

. Coronavirus (SARS-CoV2) appeared first in China late 2019 and caused an acute respiratory disease referred to as Coronavirus disease 2019 (COVID-19). SARS-CoV2 is considered by the World Health Organization (WHO) as pandemic and affected nations worldwide, leading to close borders and major economical struggle. The ongoing viral threat due to the lack of effective therapies and vaccination might prolonged this economical challenge and many businesses will face huge financial constraints leading to laying off labors, an increase in the unemployment rate, and major companies' bankruptcies. However, returning to normal business operations should be done with a safety focus and not be at the cost of global health and wellbeing. Immunity against COVID-19 is going to be a major determinant for a future safe work environment and will reduce the viral infection risk. Therefore, PI is suggesting that if an employee has antibodies against SARS-CoV-2 confirmed by serological testing, he or she could go back to work safely with taking the necessary precautions.

NCT ID: NCT04213508 Not yet recruiting - Rhinosinusitis Clinical Trials

Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients

Start date: February 1, 2020
Phase: Phase 4
Study type: Interventional

Rhinosinusitis is a common clinical problem with significant morbidity which alters patients' quality of life that has its effect on 1 out of 7 adults. It has been found that rhinosinusitis accounts for almost 26 million clinics and emergency visits per year in United states .Nasal irrigation is standard management used to treat a variety of sinonasal diseases. Furthermore, nasal irrigation decreases the need of usage other medications in rhinosinusitis .Hence, it is considered safe, inexpensive, and easy to use with no evidence of major adverse effects .Up to our knowledge, there is no clear guideline in which type (isotonic saline vs hypertonic saline) and frequency (times per day) of nasal irrigation are superior and better.