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NCT ID: NCT04442100 Recruiting - Clinical trials for Heart Valve Diseases

The Study of Biological Prosthetic Heart Valves With the "Easy Change" System

Start date: November 29, 2016
Phase: N/A
Study type: Interventional

The study of new biological heart valves with the "easy change" system, including an assessment of the basic hemodynamic characteristics of the prosthesis, complications associated with valve implantation, and general mortality

NCT ID: NCT04424134 Recruiting - COVID 19 Clinical Trials

BromhexIne And Spironolactone For CoronŠ°VirUs Infection Requiring HospiTalization

BISCUIT
Start date: May 16, 2020
Phase: Phase 3
Study type: Interventional

Patients with mild and severe COVID 19 will be randomized 1:1 into two groups: experimental, which will get bromhexine and spironolactone, and control. Patients will get investigated therapy for ten days. Change in clinical assessment score COVID 19 (CAS COVID 19) between baseline and 12th day will be evaluated as a primary endpoint. Forty-five-day risk of death or mechanical ventilation will also be assessed.

NCT ID: NCT04415827 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Energy Supply in Athletes and Untrained Persons With Bronchopulmonary Diseases

Start date: May 23, 2020
Phase: N/A
Study type: Interventional

Study of the energy supply of bicycle ergometric load in athletes and untrained persons with bronchopulmonary diseases (community-acquired pneumonia, bronchitis, chronic obstructive pulmonary disease and acute respiratory viral infections, to justify the timing of the resumption of training, as well as determination of the volume and intensity of physical activity in training and competitive processes.

NCT ID: NCT04415814 Recruiting - Fusion of Spine Clinical Trials

Unilateral Versus Bilateral Pedicle Screw Fixation for Lumbar Degenerative Diseases

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Determining the treatment strategy for patients with degenerative diseases of the spine is extremely difficult, without an accurate understanding of the nature of stress distribution in the vertebral-motor segments of the spine, as well as biomechanical changes that are associated with degenerative diseases of the spine. In this clinical study, we want to compare the use of unilateral and bilateral transpedicular fixation for treating the patients with degenerative diseases of the lumbar spine.

NCT ID: NCT04403750 Recruiting - Clinical trials for Rhegmatogenous Retinal Detachment

Combined Laser-surgical Technology of RRD Treatment

Start date: September 15, 2018
Phase: N/A
Study type: Interventional

Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment

NCT ID: NCT04400045 Recruiting - Clinical trials for Nijmegen Breakage Syndrome

Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome

Start date: May 22, 2020
Phase: Phase 2
Study type: Interventional

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT in Nijmegen breakage syndrome

NCT ID: NCT04396574 Recruiting - Migraine Clinical Trials

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

PIONEER-PEDS2
Start date: June 30, 2020
Phase: Phase 3
Study type: Interventional

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.

NCT ID: NCT04396236 Recruiting - Migraine Clinical Trials

A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

PIONEER-PEDS1
Start date: June 15, 2020
Phase: Phase 3
Study type: Interventional

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

NCT ID: NCT04395794 Recruiting - Sars-CoV2 Clinical Trials

SARS-CoV-2 Disguise Study

Disguise
Start date: May 7, 2020
Phase:
Study type: Observational [Patient Registry]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a pandemic disease with worldwide spreading. Limited data are existed regarding SARS-CoV-2 positive carriers among asymptomatic medical employees in non-profile infectious clinic, e.g. cardiovascular clinic, routinely working in the pandemic region with two million inhabitants. The aim is to test the percentage and increase of the SARS-CoV-2 positive carriers among asymptomatic medical employees in high-volume cardiovascular center in routine clinical practice.

NCT ID: NCT04393584 Recruiting - Stomach Neoplasms Clinical Trials

FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma

RusGCG-01
Start date: January 29, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Patients with resectable adenocarcinoma of the stomach or the esophagogastric junction (II-III type by Siewert) without previous therapy will be treated with one of two chemotherapy combinations before and after surgery. One half of the patients gets 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Docetaxel (FLOT), the others 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Irinotecan (FOLFIRINOX). Main objective of the study is median overall survival.