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NCT ID: NCT06331221 Recruiting - Healthy Clinical Trials

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense

Start date: November 2, 2023
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

NCT ID: NCT06320977 Recruiting - Healthy Clinical Trials

The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players

Start date: February 12, 2024
Phase: N/A
Study type: Interventional

The aim of this study isto investigate the influence of acute static stretching on the ankle joint position sense of soccer players.

NCT ID: NCT06320314 Recruiting - Hyperpigmentation Clinical Trials

Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to moderate melasma, or mild to moderate acne induced post-inflammatory hyperpigmentation, or solar lentigo.

NCT ID: NCT06317805 Recruiting - Clinical trials for Pulmonary Arterial Hypertension

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients

TripleTRE
Start date: December 6, 2023
Phase: Phase 4
Study type: Interventional

TripleTRE investigates the effect of initial triple combination therapy (oral endothelin receptor antagonist (ERA) + oral phosphodiesterase tyüe-5 inhibitor (PDE-5i) + parenteral treprostinil) compared to double oral therapy (oral ERA + oral PDE-5i) in pulmonary arterial hypertension (PAH) patients (group I) with intermediate-high risk or patients with intermediate-low risk with severe hemodynamic impairment at baseline in a prospective, randomized, unblinded setting with scope of increasing evidence for optimization of therapy concepts in PAH. The effect of initial triple combination therapy vs initial double oral therapy (standard of care (SoC)) will be measured by primary endpoint: (non)response to the assigned treatment.

NCT ID: NCT06316882 Recruiting - Gastric Cancer Clinical Trials

Opportunistic Gastric Cancer Screening

ROCGAS
Start date: February 3, 2023
Phase: N/A
Study type: Interventional

Endoscopic screening of gastric cancer combined with screening colonoscopy

NCT ID: NCT06307184 Recruiting - Clinical trials for Frozen Embryo Transfer

Assessing the Convenience of Natural Proliferative Phase Frozen Embryo Transfer

Start date: February 23, 2024
Phase:
Study type: Observational

This study will assess the convenience of the natural proliferative phase frozen embryo transfer (NPP-FET) in terms of number of number of appointments needed before cycle scheduling.

NCT ID: NCT06302764 Recruiting - Stress Clinical Trials

Emergency Medical Staff Workload Analysis

Start date: October 1, 2023
Phase:
Study type: Observational

The aim of this study is to identify trauma determinants and leverage this understanding to develop solutions applicable to the prevention and treatment of PTSD among emergency medical personnel. By categorizing stimuli associated with traumatic professional experiences, the study aims to enhance existing therapeutic protocols through exposure therapy. The specific objectives are as follows: 1. Analysis and characterization of occupational workloads among doctors and emergency medical personnel, focusing on the scale of burdens associated with PTSD symptoms. 2. Development of categories for aggravating and potentially traumatizing stimuli within the medical staff of rescue teams. 3. Examination of the feasibility of incorporating the obtained results into cognitive-behavioral therapy protocols. 4. Assessment of the potential for implementing the results in solutions utilizing virtual reality technology. 5. Formation of an interdisciplinary international research team.

NCT ID: NCT06292195 Recruiting - Pregnancy Clinical Trials

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome

VitDTracking
Start date: November 3, 2023
Phase:
Study type: Observational [Patient Registry]

The VitDTracking study focuses on the relevance of maternal vitamin D levels and their association with prematurity, aiming to improve maternal and child health outcomes, particularly by reducing avoidable preterm births. In Portugal, vitamin D levels during pregnancy have never been studied. Epidemiological data from other countries reveal a high prevalence of vitamin D deficiency/insufficiency, especially in pregnant women. The hypovitaminoses prevalence remains high even with a supplementation dosage of 400 to 600 IU/day during pregnancy (dosage used in Portugal), which is considered as a suboptimal dose. This phenomenon is associated with adverse maternal and child outcomes, such as intrauterine growth restriction, preeclampsia, cholestasis, hypertension, and gestational diabetes as major causes of prematurity. Additionally, the Portuguese population has a higher prevalence of genome alterations that confer a lower capacity to produce vitamin D from sunlight exposure. These genetic characteristics are present in about 19% of the population, representing a prevalence four times higher than the European average (19% versus 4.75%), leading to a higher predisposition to vitamin D deficiency.

NCT ID: NCT06291896 Recruiting - Clinical trials for Women's Health: Neoplasm of Breast

A Clinical Investigation to Evaluate Microwave Imaging Via MammoWave® in a Population-based Screening Program for Early Breast Cancer Detection

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

This is an open, multicentric, interventional, prospective, non-randomized clinical investigation. The first aim of the study is to confirm that MammoWave reaches sensitivity>75% and specificity>90% in breast cancer (BC) detection on 10.000 volunteers undergoing regular screening programs.

NCT ID: NCT06285864 Recruiting - Chronic Pain Clinical Trials

Sense to Act: An Interoceptive Sensibility Intervention for Musculoskeletal Pain

Start date: February 2024
Phase: N/A
Study type: Interventional

The ability to be connected and act according to bodily information is fundamental in chronic pain adjustment. This study aims to test the feasibility of an intervention designed to improve interoceptive sensibility, i.e., the ability to sense, interpret, and regulate bodily sensations in chronic musculoskeletal pain patients.