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NCT ID: NCT03537235 Completed - Clinical trials for Overweight and Obesity

Evaluation of Libramed in Obesity Treatment

ELOT
Start date: June 29, 2015
Phase: N/A
Study type: Interventional

Randomized, double-blind, placebo-controlled study aimed at evaluating the effects of a 3-months treatment with Policaptil Gel Retard on postprandial incretin hormones release and satiety in obese women

NCT ID: NCT03536884 Completed - Clinical trials for Chronic Plaque Psoriasis

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

BE RADIANT
Start date: June 13, 2018
Phase: Phase 3
Study type: Interventional

This is a study to compare the efficacy of bimekizumab versus secukinumab in subjects with moderate to severe chronic plaque psoriasis (PSO).

NCT ID: NCT03536754 Completed - Clinical trials for Focal Segmental Glomerulosclerosis

A Study of CCX140-B in Subjects With FSGS

Start date: May 17, 2018
Phase: Phase 2
Study type: Interventional

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects with FSGS to be conducted in the North America, Europe and Australia

NCT ID: NCT03535194 Completed - Psoriasis Clinical Trials

A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)

Start date: June 26, 2018
Phase: Phase 3
Study type: Interventional

The reason for this study is to see how effective and safe mirikizumab is compared to secukinumab and placebo for moderate to severe plaque psoriasis.

NCT ID: NCT03534440 Completed - Heart Failure Clinical Trials

Assessment of Diastolic Function in High Risk Patients Undergoing Major Vascular Surgery

Start date: July 1, 2018
Phase:
Study type: Observational

Patients scheduled for Thoracic Endovascular Aortic Repair (TEVAR) surgery will have transthoracic echocardiography evaluation of left ventricle diastolic function during the perioperative period.

NCT ID: NCT03533751 Completed - Atopic Dermatitis Clinical Trials

Efficacy, Safety, and Pharmacokinetic Profile of Etokimab (ANB020) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

ATLAS
Start date: June 19, 2018
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the efficacy, safety, and pharmacokinetic (PK) profiles of multiple doses of etokimab in adult participants with atopic dermatitis (AD).

NCT ID: NCT03533114 Completed - Clinical trials for Idiopathic Hypersomnia

A Multicenter Study of the Efficacy and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) With an Open-label Safety Extension

Start date: November 27, 2018
Phase: Phase 3
Study type: Interventional

This is a study of the efficacy and safety of JZP-258, an oxybate mixed-salts oral solution being developed as a low sodium alternative product for Xyrem.

NCT ID: NCT03532269 Completed - Sleep Disorder Clinical Trials

Validation of the Sleep Assessment Algorithm in the Medical Application Nightly

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The Nightly medical application prototype is a potential, non-invasive class I medical device. The application has the potential to combine both diagnostic and therapeutic procedures for sleep. At home, Nightly measures the user's motion during sleep and then records the sleep pattern from the received data. The obtained data are then used for the diagnosis of sleep disorders (REM and NREM sleep). Using acoustic and visual stimulation, the application has the capability to support the natural process of falling asleep, provide a better night's sleep by minimizing sleep deprivation and nightmares, while awakening the user at the appropriate moment (during light sleep).

NCT ID: NCT03529201 Completed - Pain, Postoperative Clinical Trials

QLB After Nephrectomy

Start date: May 7, 2018
Phase: N/A
Study type: Interventional

Oxycodone consumption and postoperative pain intensity in patients undergoing nephrectomy procedures. Of all study participants, 50% will obtain quadratus lumborum block (QLB).

NCT ID: NCT03526861 Completed - Atopic Dermatitis Clinical Trials

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

Start date: June 19, 2018
Phase: Phase 3
Study type: Interventional

Primary objective: To evaluate the efficacy of subcutaneous (SC) administration of tralokinumab compared with placebo in treating adolescent subjects (age 12 to <18 years) with moderate-to-severe AD. Secondary objectives: To evaluate the efficacy of tralokinumab on severity and extent of AD, itch, and health-related quality of life compared with placebo. To investigate the safety, immunogenicity, and tolerability of SC administration of tralokinumab compared with placebo when used to treat adolescent subjects (age 12 to <18 years) with moderate-to-severe AD.