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NCT ID: NCT00879970 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Thiazolidinedione Intervention With Vitamin D Evaluation

TIDE
Start date: May 2009
Phase: Phase 4
Study type: Interventional

This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard of care without rosiglitazone or pioglitazone in patients with type 2 diabetes who have a history of or are at risk for cardiovascular disease. The second question will compare the effects of long-term supplementation of vitamin D on death and cancer

NCT ID: NCT00876317 Terminated - Clinical trials for Tenosynovitis and Bursitis Affecting the Shoulder

Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder

Start date: November 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety two oral doses of etoricoxib (60 mg and 90 mg) daily in acute soft tissue rheumatism affecting the shoulder.

NCT ID: NCT00865592 Terminated - Type 2 Diabetes Clinical Trials

Long-term Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus

Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that dutogliptin/PHX1149T is safe and tolerable.

NCT ID: NCT00850239 Terminated - Clinical trials for Type 2 Diabetes Mellitus

Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the efficacy of dutogliptin over 26 weeks (as evidenced by placebo-corrected changes in HbA1c relative to baseline), to demonstrate safety and tolerability of dutogliptin, and to demonstrate changes in fasting plasma glucose over 26 weeks.

NCT ID: NCT00831441 Terminated - Clinical trials for Acute Coronary Syndrome

Phase III Acute Coronary Syndrome

APPRAISE-2
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if apixaban is superior to placebo for preventing cardiovascular death, non-fatal myocardial infarction, or ischemic stroke in subjects with a recent acute coronary syndrome

NCT ID: NCT00805467 Terminated - Clinical trials for Rheumatoid Arthritis

Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of this new research study is to gain additional information about how safe and effective R935788 is over a longer period of time.

NCT ID: NCT00796666 Terminated - Clinical trials for Pulmonary Hypertension

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Start date: May 2009
Phase: Phase 3
Study type: Interventional

As monotherapy for pulmonary arterial hypertension (PAH) begins to fail additional therapies are introduced. Although co-administration of sitaxsentan and sildenafil is well tolerated the controlled safety/efficacy database of the combination is limited.

NCT ID: NCT00795639 Terminated - Clinical trials for Pulmonary Hypertension

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Start date: December 2008
Phase: Phase 3
Study type: Interventional

This protocol is for subjects with pulmonary arterial hypertension and is the first of 3 studies forming the Sitaxsentan efficacy and safety trial with Randomized Prospective Assessment of Adding Sildenafil (SR-PAAS) program.

NCT ID: NCT00768300 Terminated - Clinical trials for Idiopathic Pulmonary Fibrosis

(ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF

ARTEMIS-IPF
Start date: December 2008
Phase: Phase 3
Study type: Interventional

The ARTEMIS-IPF study was conducted to determine if ambrisentan was effective in delaying disease progression and death in participants with idiopathic pulmonary fibrosis (IPF), to evaluate its safety, and to evaluate its effect on development of pulmonary hypertension, quality of life, and dyspnea (shortness of breath) symptoms in this participant population. Participants were randomized in a 2:1 ratio to receive ambrisentan or placebo, respectively. Participation in the study was to be up to 4 years, depending on how long it would take to enroll participants and observe study events. After randomization, visits to the clinic took place every 3 months, and laboratory procedures were performed every month.

NCT ID: NCT00741845 Terminated - Bacterial Vaginosis Clinical Trials

Prevention of Persistence of Bacterial Vaginosis

Start date: June 2008
Phase: Phase 3
Study type: Interventional

This purpose of this study will be to conduct a double-blind, randomized, controlled clinical trial to determine the association between intravaginal high dose metronidazole (750mg), intravaginal high dose metronidazole combined with an antifungal agent(750mg metronidazole + 200mg miconazole) and low dose (37.5mg) intravaginal metronidazole, with the rate of persistent bacterial vaginosis.