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NCT ID: NCT00425919 Terminated - Diabetes Mellitus Clinical Trials

Study Evaluating PPM-204 In Subjects With Type 2 Diabetes

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to learn whether PPM-204 has an effect on lowering blood glucose (blood sugar) levels and is safe in treating people with type 2 diabetes.

NCT ID: NCT00414206 Terminated - Clinical trials for Macular Degeneration

Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD)

Start date: March 2007
Phase: Phase 2
Study type: Interventional

This is a Phase II randomized, double-masked study comparing the safety and efficacy of ATG003 (mecamylamine HCl) 1.0% and 0.3% ophthalmic solutions to placebo in patients with neovascular ("wet") age-related macular degeneration (NV-AMD).

NCT ID: NCT00412776 Terminated - Clinical trials for Head and Neck Cancer

Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer

Start date: December 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of Proxinium plus best supportive care with best supportive care only for patients with squamous cell head and neck cancer.

NCT ID: NCT00412620 Terminated - Schizophrenia Clinical Trials

An Evaluation of the Safety and Efficacy of ABT-925 in Subjects With Acute Exacerbation of Schizophrenia

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The objective of this study is to explore the safety and efficacy of ABT-925 involving patients who meet the DSM-IV-TR (Diagnostic and Statistical Manual of Medical Disorders, Fourth Edition Text Revision) criteria for an acute exacerbation of schizophrenia or schizoaffective disorder.

NCT ID: NCT00407797 Terminated - Partial Seizures Clinical Trials

Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy Trial

PREPS MEXICO
Start date: March 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the clinical improvement by partial seizures reduction, safety and tolerability of subjects having partial epilepsy related to the adjunction of pregabalin BID (75 to 300mg day titration, BID) to existing standard AED (Antiepileptic drugs).

NCT ID: NCT00406744 Terminated - Clinical trials for Age Related Macular Degeneration

Efficacy of Retreatments With Intravitreal Bevacizumab

Start date: May 2006
Phase: Phase 3
Study type: Interventional

Choroidal neovascularization is a leading cause of visual loss in people older than 60 years and for its treatment there had been performed multicentric studies with Lucentis (Ranibizumab) with a significant improval of visual acuity. In our institution we evaluated efficacy of bevacizumab in several pathologies but we dont know what would be the results if we use the same dose several times. Our purpose was to determine the efficacy of bevacizumab for improve or stabilize visual acuity with two or more intravitreal inyections of bevacizumab.

NCT ID: NCT00406653 Terminated - Crohn's Disease Clinical Trials

A Study of Abatacept in Patients With Active Crohn's Disease

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn if abatacept can improve signs and symptoms of active Crohn's Disease in patients who have not had an adequate response to other therapies. The safety of this treatment will also be studied.

NCT ID: NCT00405808 Terminated - Obesity Clinical Trials

Rimonabant in Abdominally Obese Patients With Impaired Fasting Blood Glucose

PRADO
Start date: December 2006
Phase: Phase 3
Study type: Interventional

Primary objective: To determine the effect of Rimonabant 20mg on the co-primary endpoint including Fasting Plasma Glucose (FPG), HDL-Cholesterol (HDL-C) and triglyceride (TG) levels over a period of 12 months when prescribed with a mild hypocaloric diet in abdominally obese patients with impaired fasting blood glucose and with or without associated comorbidities. Main Secondary objectives: To determine the effect of 12 months Rimonabant treatment versus placebo on changes in waist circumference (WC), body weight, glycemic parameters and lipid parameters. To assess the safety of 12 months Rimonabant treatment versus placebo in these patients.

NCT ID: NCT00404209 Terminated - Retinal Detachment Clinical Trials

Pressurized PPV 23GA Vitrectomy in Complicated Diabetic Tractional Retinal Detachment

Start date: March 2007
Phase: Phase 3
Study type: Interventional

To investigate the feasibility and advantages of using pressurized perfluorocarbon liquid (PCL) perfusion to remove vitreous during suction-cutting 23 GA vitrectomy using a dual, dynamic drive (3D)technology, in complicated retinal detachment surgeries.

NCT ID: NCT00397683 Terminated - Osteoarthritis Clinical Trials

A 52-Week Study to Assess the Effects of MK0822 on Knee Osteoarthritis (MK-0822-011)

Start date: October 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test MK0822 on disease activity in patients with osteoarthritis in the knee. Disease modifying activity of MK0822 will be assessed by measurements of knee cartilage using Magnetic Resonance Imaging (MRI) of the knee. This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).