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NCT ID: NCT04888572 Enrolling by invitation - Peri-Implantitis Clinical Trials

Evaluation of the Novel Implant Disease Risk Assessment : a Retrospective Study (IDRA)

IDRA
Start date: May 11, 2021
Phase:
Study type: Observational

Given the novelty of this risk assessment tool, this study will be interested in evaluating its effectiveness through a retrospective approach. The IDRA risk will be analyzed at the time of loading the implant (s) in patients who have already placed an implant (s) during the last five years at the Department of Periodontology and Oral Surgery using the information collected from the periodontal file previously completed. Therefore, patients whose IDRA has been calculated will be called for a clinical and radiological examination to verify the development or not of peri-implantitis or the loss of the implant. In this way, this tool for predicting peri-implant disease will be evaluated to see if it is really effective.

NCT ID: NCT04877522 Recruiting - Clinical trials for Chronic Myelogenous Leukemia

Asciminib Roll-over Study

Start date: August 30, 2022
Phase: Phase 4
Study type: Interventional

This is a long term safety study for patients who have completed a Novartis sponsored asciminib study and are judged by the investigator to benefit from continued treatment

NCT ID: NCT04870541 Recruiting - Shivering Clinical Trials

Nefopam Versus Ondansteron for Prevention of Post Spinal Shivering.

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

Spinal anesthesia affects the homeostatic systems resulting in intraoperative hypothermia and subsequently shivering. In fact, shivering may be seen after this technique in 30 to 40% of cases . Ondansetron and Nefopam have been used to prevent intraoperative shivering . However, no prospective, randomized, double-blind study has been conducted to this date in order to compare nefopam with ondansetron in the prevention of post-spinal anesthesia shivering. The primary objective of this prospective, randomized, double-blind study is to compare the incidence and intensity of shivering after spinal anesthesia for non-obstetric surgery in 2 groups of patients. Group A: Patients receiving 8 mg of ondansetron diluted in 20 ml of 0.9% normal saline over 30 minutes as they arrive to the operating theater(75 patients). • Group B: Patients receiving 20 mg of nefopam diluted in 20 ml of 0.9% normal saline over 30 minutes as they arrive to the operating theater (75 patients)

NCT ID: NCT04827888 Completed - Obesity Clinical Trials

Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures

BMIORTHO
Start date: January 1, 2012
Phase:
Study type: Observational [Patient Registry]

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries using a retrospective cohort study design. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities.

NCT ID: NCT04822454 Completed - Clinical trials for Medical Students Well-being and Anxiety

Early Exposure of Medical Students to Night Shifts: Impact on Well-being and Anxiety

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This is an interventional study assessing the impact of 'shadowing night shifts' early during medical school, on the wellbeing and level of anxiety of a students during their first official night shifts.

NCT ID: NCT04817670 Completed - Sickle Cell Disease Clinical Trials

Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease

ViSionSerenity
Start date: June 18, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the effect of VIT-2763 on markers of hemolysis (breakdown in red blood cells) in sickle cell disease (SCD). The safety, tolerability and clinical beneficial effects of VIT-2763 for the treatment of SCD are also explored.

NCT ID: NCT04813471 Recruiting - Covid19 Clinical Trials

Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH

Start date: January 20, 2021
Phase: Phase 3
Study type: Interventional

COVID-19 Infection has been found to cause endothelial dysfunction and most of the adverse events stem to this mechanism. So we seek to target endothelial dysfunction in critically Ill patients with covid by giving them an endothelial protocol ( L-arginine, Folic Acid, Statin, Nicorandil, Vitamin B complex) and monitor clinical outcome in those patients.

NCT ID: NCT04813367 Not yet recruiting - Clinical trials for Twisted Fallopian Tube

Twisted Fallopian Tubes

Tubes
Start date: April 2021
Phase:
Study type: Observational

Isolated tubal torsion is a very rare event already in adults (1: 1.5 million women), it remains exceptional in children without being able to find a prevalence in the literature. The causes can be malformative or idiopathic, but even that remains unknown. Because of the scarcity, surgical treatment is not standardized and left to the good care of the surgeon in charge.

NCT ID: NCT04790149 Completed - Clinical trials for Spinal Cord Injuries

Effectiveness of NEUROM Combined With tDCS to Guide Motor Recovery in Paraplegics Patients

NEUROM
Start date: December 1, 2017
Phase: N/A
Study type: Interventional

In a traditional view going back to 1800, spinal cord has been described as a protected bundle of nerves that connects the brain to the body. Galen contended that spinal cord mediates motor, sensory and some of the autonomic functions below the neck. Traumatic Spinal Cord Injury (TSCI) is a catastrophic unexpected and devastating event that can be occurred along the spinal column (cervical, thoracic, and lumbar). A global-incident rate (2007) is estimated at 23 TSCI cases per million (179312 cases per annum). TSCI can often results in a life-threatening condition that includes varying degrees of motor paralysis and sensory loss and impairment of bowel, bladder, sexual, and other physiologic functions. In this study, investigators suggest a new experimental rehabilitative protocol for TSCI patients called Neural Motor Recruitment Method (NEUROM). This method is based on the mentioned histological and/or functional reorganization model after TSCI, on the MI concepts and the targeted sensory inputs related to motor recovery. The hypothesis here is that NEUROM can enhance sparing- induced plasticity and increase motor and sensory recovery in SCI patients especially when combined to tDCS.

NCT ID: NCT04783220 Recruiting - Early Intervention Clinical Trials

PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)

PREPARE
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed results. In low to middle-income countries, clinically relevant and effective low cost interventions empowering parents have yet to be established.