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NCT ID: NCT03827811 Recruiting - Clinical trials for Multi-drug Resistant Tuberculosis

Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB Tuberculosis

PandrTB
Start date: January 30, 2020
Phase:
Study type: Observational

PandrTB is a study of the pharmacokinetics(PK) and pharmacodynamics(PD) of bedaquiline, delamanid, clofazimine, linezolid, moxifloxacin, levofloxacin and pyrazinamide used in novel combinations to treat multidrug-resistant tuberculosis(MDR-TB).

NCT ID: NCT03824457 Completed - Pneumonia Clinical Trials

Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Pneumonia

Start date: January 8, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of pneumonia. Half of participants will receive Rheosorbilact® in complex therapy, while the other half will receive Ringer's Lactate in complex therapy.

NCT ID: NCT03764085 Completed - Sepsis Clinical Trials

Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.

Start date: December 6, 2016
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of sepsis. Half of participants will receive Rheosorbilact® in complex therapy, while the other half will receive Ringer's Lactate in complex therapy.

NCT ID: NCT03669835 Completed - Hepatitis C Clinical Trials

The Sublimated Mare Milk Supplement in Hepatitis C

Start date: March 28, 2018
Phase: N/A
Study type: Interventional

This clinical trial studies the effect of sublimated mare milk supplement on patients with hepatitis C.

NCT ID: NCT03667469 Completed - Obesity Clinical Trials

Study of the Life Expectancy of Patients With Metabolic Syndrome After Weight Loss:

LIFEXPE-RT
Start date: May 24, 2018
Phase: N/A
Study type: Interventional

Background and study aims: Surgical and non-surgical normalization of body weight with obesity leads to a significant improvement in health and regression of metabolic syndrome. But as the reduction in body weight with obesity changes the life expectancy remains not clear enough. The use of endoscopic staplers does not exclude the emergence of serious complications of surgery, for example, including bleeding and leakage in the stapler suture line. Therefore, the advantages of using a band in the bariatrics are justified from a security standpoint. Currently, the gastric bypass is increasingly performed in the version of the mini gastric bypass (MGB). Another name for the procedure: one anastomosis gastric bypass (OAGB). The proposal to use for the staple-free (stepleless or steplerless) creation of a pouch (band-separated gastric bypass) with use for band a vascular prosthesis is justified, but it requires comparison of this method with a stapler variant. An important issue is comparing surgical and non-surgical weight loss with obesity and metabolic syndrome and comparing life expectancy with confirmation of changes in telomere length. This study compares loss of weight, changes in other health conditions that the patient may have (co-morbidities, such as diabetes), telomere length, quality of life, the number of complications and side effects, the degree of complexity of the surgical technique and operating costs of a new laparoscopic band-separated mini- gastric bypass (LBSMGB) procedure compared with the standard stapler (linear cutter) - separated mini-gastric bypass (LSSMGB). Additionally, surgical treatment will be compared with non-surgical treatment (hypocaloric diet therapy). Who can participate? Obese adult patients with a BMI of between 30 kg/m2 and 50 kg/m2. What does the study involve? Participants are randomly allocated to one of three groups. Those in the first (A) group undergo the laparoscopic band-separated mini-gastric bypass procedure. Those in the second (B) group undergo the linear cutter stapler-separated mini-gastric bypass procedure. In three (C) group including standard lifestyle intervention on weight and hypocaloric diet therapy. All patients are then followed up one month after surgery and again after 6 and, finally, 12 months after surgery where the changing body mass index, changes in co-morbidities, change telomere length and quality of life are assessed.

NCT ID: NCT03665519 Completed - Clinical trials for Primary Biliary Cirrhosis

Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis

Start date: January 3, 2018
Phase: N/A
Study type: Interventional

This study evaluates the effect of sublimated mare milk supplement on patients with biliary cholangitis

NCT ID: NCT03664596 Completed - Clinical trials for Non-alcoholic Steatohepatitis

Therapeutic And Dietary Effects Of The Sublimated Mare's Milk Supplement In Patients With Non-Alcoholic Steatohepatitis

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the dietary and therapeutic effect of supplement consisting of sublimated mare milk among patients with non-alcoholic steatohepatitis.

NCT ID: NCT03663374 Completed - Alcohol Dependence Clinical Trials

Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence

Start date: November 18, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study was to assess efficacy and safety of the study drug Odelepran, 125 mg as compared to placebo in the treatment of alcohol dependence in adult outpatients.

NCT ID: NCT03657836 Completed - Acute Bronchitis Clinical Trials

The Sublimated Mare Milk Supplement's Effect on Gut Mucosal Lining After Antibiotics

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

This clinical trial studies the effect of sublimated mare milk supplement on gut microbiome of patients with acute bronchitis.

NCT ID: NCT03594877 Completed - Psoriasis Clinical Trials

Effect of Sublimated Mare Milk Supplement on Gut Microbiome in Psoriasis Patients

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the effect of dietary supplement consisting of sublimated mare milk on intestinal microbiota among psoriasis and healthy participants.