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NCT ID: NCT03160807 Recruiting - Clinical trials for Urinary Tract Infection

Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections

Levolet-KZ16
Start date: April 15, 2017
Phase: Phase 4
Study type: Interventional

Study is planned to evaluate safety and efficacy of Levolet in patients with complicated UTI

NCT ID: NCT03028116 Completed - Influenza, Human Clinical Trials

Reactogenicity, Safety and Immunogenicity Study of a Allantoic Split Inactivated Seasonal Influenza Vaccine

VSI
Start date: May 2016
Phase: Phase 1
Study type: Interventional

The study is a single centre, phase I, double-blind, randomized, placebo-controlled trial that explored the safety and immunogenicity of single dose a allantoic split inactivated seasonal influenza vaccine in healthy adults.

NCT ID: NCT03022461 Recruiting - Clinical trials for Advanced Refractory Left Ventricular Heart Failure

HeartMate 3 CE Mark Study Long Term Follow-up

HM3 CE LTFU
Start date: June 2016
Phase: N/A
Study type: Observational

The purpose of this clinical investigation is to report the long term survival and incidence of adverse events in the patients who were implanted with HM3 in the CE Mark Study and continue to be ongoing with the HeartMate 3 LVAS after the CE Mark Study 2 year follow-up. The study will be a single arm, prospective, multi-center, non-blinded and non-randomized study, intended to report on the long term use of the HeartMate 3 LVAS in those patients that completed the 2-year follow-up in the HeartMate 3 CE Mark study.

NCT ID: NCT03017378 Completed - Tuberculosis Clinical Trials

Reactogenicity, Safety and Immunogenicity of a TB/FLU-01L Tuberculosis Vaccine

Start date: October 2013
Phase: Phase 1
Study type: Interventional

The study is a single centre, phase I, open, randomized, by intranasal and sublingual application trial that explored the safety and immunogenicity of 2 doses (Day 1 and Day 21) TB/FLU-01L tuberculosis vaccine in BCG-vaccinated healthy adult subjects aged 18-50 years.

NCT ID: NCT03016143 Completed - Influenza Clinical Trials

Immunogenicity and Safety Study of Allantoic Split Inactivated Seasonal Influenza Vaccine (VSI)

Start date: October 2016
Phase: Phase 2
Study type: Interventional

The study is a single centre, phase II, double-blind, randomized, comparative trial that explored the immunogenicity and safety of single dose a allantoic split inactivated seasonal influenza vaccine and VAXIGRIP vacccine in healthy adults the two age groups (in persons 18 to 60 years of age and older than 60 years).

NCT ID: NCT03014193 Not yet recruiting - Medical Abortion Clinical Trials

Simplifying First Trimester Medical Abortion Follow-up

Start date: January 2017
Phase: N/A
Study type: Observational

This study evaluates the usability of the multilevel pregnancy test among women undergoing medical abortion.

NCT ID: NCT02926534 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Cross-Sectional Study of COPD Prevalence Among Smokers, Ex-smokers and Never-Smokers in Almaty, Kazakhstan

Start date: September 2016
Phase: N/A
Study type: Observational

The purpose of this study is to assess the prevalence of COPD among individuals aged 35 - 59 years based results of spirometry before and after bronchodilator, presence of structural changes in lungs (emphysema, inflammatory changes and thickening of the walls of the large and small airways)detected by computer tomography as well as the symptoms of COPD. The study has three study groups: smokers of conventional cigarettes; those who had quit smoking 1 - 5 years ago, and those who haven't smoked cigarettes.

NCT ID: NCT02796027 Not yet recruiting - Clinical trials for Human Immunodeficiency Virus

BRIDGE: Improving HIV Service Delivery for People Who Inject Drugs

Start date: August 2016
Phase: N/A
Study type: Interventional

Scaling up integrated, cost-efficient HIV services for people who inject drugs (PWID) in Needle Syringe Programs (NSPs) is urgently needed in Kazakhstan, where only one-third of the estimated 19,000 HIV-positive PWID are ever linked to HIV care and only 10% initiate ART with 4% achieving viral suppression. The study's aim is to evaluate the implementation, effectiveness, and sustainability of an integrated HIV service model in 24 NSPs located in 4 Kazakhstani cities. This model will employ highly effective strategies that will include peer-driven recruitment of PWID in NSPs using social network strategies (SNS), integrating rapid HIV testing in NSPs with HIV Care Clinic nurses, and linking HIV positive PWID in NSPs to HIV care using the ARTAS (Anti-Retroviral Treatment and Access to Services) case management model. Findings will have important public health implications for improving HIV service delivery for PWID in the Central Asian region and other countries with injection driven epidemics.

NCT ID: NCT02786615 Not yet recruiting - HIV Clinical Trials

Increasing MSM in the Continuum of Care in Kazakhstan

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

This study addresses the disproportionate representation of men who have sex with men (MSM) in the human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) pandemic in Kazakhstan, a country that has seen some of the largest growth in new HIV infections since the turn of the century. Using a stepped wedge trial across 4 cities in Kazakhstan, the proposed study will test a strategic and innovative social network-based intervention for MSM who use drugs in Kazakhstan as a strategy to increase their numbers in the HIV continuum of care as well as services that address issues that co-occur with HIV, including drug abuse, Hepatitis C Virus (HCV) infection, and other sexually transmitted infections.

NCT ID: NCT02754765 Recruiting - Clinical trials for Tuberculosis, Multidrug-Resistant

Evaluating Newly Approved Drugs for Multidrug-resistant TB

endTB
Start date: December 2016
Phase: Phase 3
Study type: Interventional

endTB Clinical Trial a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of five new, all-oral, shortened regimens for multidrug-resistant tuberculosis (MDR-TB).