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NCT ID: NCT03425552 Completed - Schizophrenia Clinical Trials

A Clinical Study to Evaluate the Bioavailability Between Two Products Containing Paliperidone 100 mg in the Form of a Prolonged Release Suspension for Injection in Patients With Schizophrenia Who Are Already Stabilized in This Treatment

Start date: March 11, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical study will compare the equivalence of two products containing Paliperidone 100 mg in the form of a prolonged release suspension for injection in patients affected by schizophrenia who are already receiving this treatment. Each patient will receive both products (Test and Reference). In total, each patient will receive 10 doses (five doses of the Test product and five doses of the Reference product; one dose every 28 days). Furthermore, the two products (Test and Reference) will be compared with regard to their safety and tolerability.

NCT ID: NCT03348046 Completed - Clinical trials for Rheumatoid Arthritis

Safety Study of Remsima® (Infliximab) in Rheumatoid Arthritis Patients in Jordan

PASSRRA
Start date: March 23, 2017
Phase:
Study type: Observational

The purpose of this observational study is to assess the safety and effectiveness of biosimilar Infliximab in patients with rheumatoid arthritis(RA) in Jordan where no visits or intervention(s) additional to the daily practice will be performed

NCT ID: NCT03326505 Completed - Multiple Sclerosis Clinical Trials

Allogenic Mesenchymal Stem Cells And Physical Therapy for MS Treatment

Start date: September 25, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims at expanding Umbilical Cord derived Mesenchymal Stem Cells (MSCs) to a clinical scale according to Good Laboratory Practice and study its efficacy when compared to a Supervised Physical Therapy Program alone.

NCT ID: NCT03310307 Completed - Clinical trials for Vitamin D Deficiency

Vitamin D3 Treatment and Homocysteine Concentrations Among Overweight Reproductive Women

Start date: April 1, 2016
Phase: Phase 2
Study type: Interventional

100 overweight reproductive vitamin D deficient women were divided into two groups; vitamin D (n = 50) and placebo (n = 50). Vitamin D group received treatment dose of 50,000 IU of vitamin D3 per week for 2 consecutive months and placebo group received placebo tablets similar in size, shape and color to vitamin D3 for 2 months also. Total homocysteine concentrations were measured before intervention (basal), on 30 days (one month) and on 60 days (2 months) of intervention. Changes in means of homocysteine concentrations for placebo and vitamin D group over time showed significant difference on 30 and 60 days of intervention. Mean comparisons of homocysteine concentrations and standard error of the means before and after intervention showed statistical significant decrease in homocysteine concentrations among vitamin D group.

NCT ID: NCT03273634 Completed - Arrhythmia Clinical Trials

The Effect of Proton Pump Inhibition on Palpitations

Start date: May 20, 2017
Phase: Phase 4
Study type: Interventional

Feeling of palpitations with no clear arrhythmia is frequently encountered in clinical practice. The majority of these patients have documented sinus rhythm even while having symptoms. Gastrointestinal association with such symptoms was first described by Ludwig von Roemheld (1871-1938).The investigators thought to investigate the effect of proton pump inhibition in patients with feeling of palpitations but no clear cause.

NCT ID: NCT03254069 Completed - Dental Caries Clinical Trials

Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children

OBF
Start date: November 2011
Phase: N/A
Study type: Interventional

The aim of this study was to determine if restoring primary molars with SSCs would improve children's OBF.

NCT ID: NCT03243227 Completed - Clinical trials for Carpal Tunnel Syndrome

Effectiveness of Neurodynamic Techniques for the Treatment of Carpal Tunnel Syndrome

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome CTS is the most common peripheral neuropathy seen in clinic. It results in marked functional limitations of patients. Most patients undergo surgical release which places a heavy burden on health system. Neurodynamic exercise is claimed to be an effective physiotherapy treatment for these patients. It is a practical and complications-free treatment which can be used as a home exercise program. This study aims to investigate the effect of median nerve gliding exercise on symptoms severity and functional limitation in CTS patients.

NCT ID: NCT03176238 Completed - Clinical trials for Post Menopausal Breast Cancer

Study in Post-menopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer

EVEREXES
Start date: March 29, 2013
Phase: Phase 3
Study type: Interventional

This international, multi-center, open-label, single-arm study evaluated the safety and tolerability profile of everolimus in post-menopausal women with HR positive, HER2 negative locally advanced or metastatic breast cancer after documented recurrence or progression following a non-steroidal aromatase inhibitors (NSAI) therapy in Novartis Oncology emergent growth market (EGM) countries.Data was presented by Asian countries vs Non-Asian countries to confirm no difference in safety and efficacy. Summary statistics were presented.

NCT ID: NCT03175367 Completed - Clinical trials for Hypercholesterolemia

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Start date: November 10, 2017
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the reduction of LDL-C by evinacumab in comparison to placebo after 16 weeks in patients with primary hypercholesterolemia (HeFH, or non-HeFH with a history of clinical ASCVD) with persistent hypercholesterolemia despite receiving maximally-tolerated LMT. Persistent hypercholesterolemia is defined as LDL-C ≥70 mg/dL (1.81 mmol/L) for those patients with clinical ASCVD and LDL-C ≥100 mg/dL (2.59 mmol/L) for those patients without clinical ASCVD.

NCT ID: NCT03112603 Completed - Clinical trials for Graft-versus-host Disease (GVHD)

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Start date: June 29, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy of ruxolitinib against best available therapy in participants with steroid-refractory chronic graft-versus-host disease (SR cGvHD).