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NCT ID: NCT06450275 Completed - HIV Infections Clinical Trials

Bioequivalence Study to Compare Dolutegravir 50mg Film-coated Tablets

Start date: January 3, 2024
Phase: Phase 1
Study type: Interventional

Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Dolutegravir 50mg film-coated tablets (50mg Dolutegravir) versus Tivicay 50mg film-coated tablets (50mg Dolutegravir) in healthy subjects under fasting conditions.

NCT ID: NCT06450262 Completed - Type2diabetes Clinical Trials

Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets

Start date: January 4, 2024
Phase: Phase 1
Study type: Interventional

Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Empagliflozin/ Metformin HCl 12.5mg/1000mg film-coated tablets (12.5mg Empagliflozin / 1000mg Metformin HCl) versus Synjardy® 12.5mg/1000mg film-coated tablets (12.5mg Empagliflozin/ 1000mg Metformin HCl) in healthy subjects under fed conditions.

NCT ID: NCT06429488 Completed - Clinical trials for Inflammatory Bowel Diseases

Obsessive-compulsive Disorder, Depression and Anxiety Among Patients With Crohn's Disease

Start date: September 1, 2022
Phase:
Study type: Observational

Introduction: Crohn's disease (CD) and obsessive-compulsive disorder (OCD) are two distinct medical conditions that affect millions of people worldwide. While numerous studies have explored anxiety and depression in CD, there is a notable lack of research about the link between OCD and CD. The aim of the study is to look for a relation between these seemingly unrelated conditions. Methods: Patients with a diagnosis of Crohn's disease were given four different questionnaires in order to assess for the presence of obsessive-compulsive disorder, depression, and anxiety symptoms using the OCI-R score, DASS-21, PHQ-9, and GAD-7. The same questionnaires were used to assess healthy controls for similar symptoms.

NCT ID: NCT06401252 Completed - Nurse's Role Clinical Trials

Mindfulness for Nurses' Psychological Health

Start date: January 30, 2022
Phase: N/A
Study type: Interventional

Background: Nurses who worked with patients with COVID-19 in hospitals have experienced several threatening and challenging situations, negatively affecting psychological health. M-health-based mindfulness-based interventions were found to improve psychological health in various populations. Aim: The purpose of this study is to assess the effectiveness of a m-Health-based mindfulness-based intervention on anxiety, depression, stress among Jordanian registered nurses taking care of COVID-19 patients. Methodology: The study was conducted using a pretest post-test randomized controlled design. One hundred and two nurses were recruited from a Jordanian Hospital and randomly distributed into experimental group (n=51) and control group (n= 51). The study data were collected using a self-report questionnaire working in the King Abdullah University hospital at baseline and at the end of intervention. For five weeks, the experimental group had five individual 30-minute MBI sessions. An audio-based MBI that was given to them via the WhatsApp served as the research intervention. A self-report questionnaire was used to collect the study data as follows: 1) demographic characteristics and 2) Mindful Attention Awareness, and 3) Scale the Depression, Anxiety, and Stress Scale (DASS-21). The study outcomes were measured at baseline and at the end of the intervention. Data were analyzed using the Statistical Package for Social Science (SPSS), Version 26.

NCT ID: NCT06400381 Completed - Mindfulness Clinical Trials

Effectiveness of Mindfulness-Based Interventions on Professional Quality of Life, Work Engagement, and Sleep Quality

MBI
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to examine the impact of a mindfulness-based intervention on professional quality of life, work engagement, and sleep quality in pediatric and neonatal nurses. A quasi-experimental pretest-posttest design will be used to evaluate the effectiveness of the mindfulness-based intervention on professional quality of life, work engagement, and sleep quality among pediatric and neonatal nurses. Pediatric and neonatal nurses (number = 208) will be conducted at King Abdullah Hospital, Rahmah Hospital, Al-Basher Hospital, and Jordan University Hospital after getting the Institutional Review Board (IRB) approval from Jordan University of Science and Technology, in addition to the IRB from the Ministry of Health. The nurses will be allocated into two groups, one as an interventional group and one as a control group, and the participants will be asked to complete the pretest questionnaire (baseline pre-intervention) and then the post-test at the end of the intervention (8 weeks after baseline). Data will be collected using online questionnaires of the study variables and a demographic questionnaire for the participants. Data will be analyzed using the Statistical Package for the Social Sciences (version 26).

NCT ID: NCT06366542 Completed - Clinical trials for Vestibular Dizziness

Virtual Reality in People With Persistent Postural-Perceptual Dizziness: RCT

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study aimed to compare the effectiveness of virtual reality (VR) and vestibular rehabilitation therapy (VRT) in enhancing balance in individuals with Persistent Postural-Perceptual Dizziness (PPPD). The experimental group received VR combined with VRT and optokinetic stimulation, while the control group received VRT and optokinetic stimulation. The study involved 42 individuals diagnosed with PPPD and administered ten intervention sessions over six weeks. The study also examined the impact of VR on various aspects of PPPD, including dizziness, visual vertigo, mental well-being, sleep quality, fall risk, and overall quality of life.

NCT ID: NCT06359483 Completed - Healthy Adults Clinical Trials

The Impact of Meal Frequency on Bone Remodeling in Healthy Adults

Start date: June 19, 2021
Phase: N/A
Study type: Interventional

The study aimed to investigate the effect of meal frequency on bone remodeling using the marker Procollagen Type 1 N-terminal propeptide (P1NP). Thirty healthy adult males from Jordan participated in a randomized controlled intervention trial. They were randomly assigned to three or eight daily meals for three consecutive days over two phases. Blood samples were obtained at the beginning and end of each phase, and P1NP levels were analyzed. The results showed a substantial drop in P1NP levels compared to the baseline, indicating that meal frequency influences bone development. There were no significant changes between the groups eating three and eight meals per day. The study emphasizes the importance of dietary patterns in bone health and advises additional research to understand the relationship between meal frequency and bone metabolism.

NCT ID: NCT06289816 Completed - Clinical trials for Minimally Invasive Surgery

Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes

Start date: January 1, 2015
Phase:
Study type: Observational

This retrospective cohort study examines the effectiveness of minimally invasive spleen-preserving surgeries compared to total splenectomy for treating primary splenic hydatidosis in Jordan. Covering 18 patients from January 2015 to June 2021, the research highlights similar recurrence rates between both surgical approaches, emphasizing the benefits of spleen preservation in maintaining immune function and reducing septic risks, particularly in pediatric patients.

NCT ID: NCT06271148 Completed - Surgery Clinical Trials

Career and Lifestyle Among Female Surgeons in Jordan

Start date: February 3, 2023
Phase:
Study type: Observational

A study conducted to evaluate the female surgeons in Jordan from different lifestyle

NCT ID: NCT06257199 Completed - Healthy Patients Clinical Trials

Real-time Measurement of Intra-canal Temperature in Vivo

Start date: May 29, 2023
Phase:
Study type: Observational [Patient Registry]

Included patients will be attending the dental clinics for a root canal treatment. After explaining the procedure and obtaining their consent, the intracanal temperature of the treated tooth will be measured after irrigation with normal saline at 2 different temperatures: 22- and 45-degree Celsius. The intraoral temperature will be recorded using a thermocouple probe inserted inside the canal at the mid-root level. Intraoral temperature will be recorded at the same time using another probe attached to the lingual mucosa. A video will be recorded for the temperature changes over 180 seconds duration starting from the time of placing the irrigation solution into the canal.