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NCT ID: NCT01078051 Terminated - Clinical trials for Coronary Artery Disease

Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion (DECISION-CTO)

Start date: March 22, 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of drug-eluting stent implantation compared to optimal medical treatment in patients with chronic total occlusion.

NCT ID: NCT01077154 Terminated - Breast Cancer Clinical Trials

Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE)

Start date: June 2, 2010
Phase: Phase 3
Study type: Interventional

This randomized phase 3 trial is studying the effect of denosumab to see if it can prevent disease recurrence in the bone or in any other part of the body, when it is given as adjuvant therapy for women with early-stage breast cancer, who are at high risk of disease recurrence.

NCT ID: NCT01061580 Terminated - Clinical trials for Congestive Heart Failure

BMAC Enhanced Coronary Artery Bypass Grafting (CABG)

Start date: May 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Injection of concentrated bone marrow cells into the myocardium during CABG procedure.

NCT ID: NCT01049217 Terminated - Neuropathy Clinical Trials

Pregabalin Versus Placebo In The Treatment Of Neuropathic Pain Associated With HIV Neuropathy

Start date: April 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of pregabalin compared to placebo in reducing neuropathic pain associated with HIV neuropathy.

NCT ID: NCT01039376 Terminated - Clinical trials for Leukaemia, Lymphocytic, Chronic

Ofatumumab Maintenance Treatment vs No Further Treatment in Relapsed CLL Responding to Induction Therapy

PROLONG
Start date: May 6, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study was to determine if maintenance therapy with ofatumumab would prolong remission in patients with CLL who have responded to second or third line treatment. This study would also evaluate the safety of ofatumumab maintenance compared to observation (the current standard of care). This study was co-developed with the HOVON and NORDIC CLL group and would be conducted as a collaborative effort with GSK.

NCT ID: NCT01035801 Terminated - Clinical trials for Type 1 Diabetes Mellitus

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Insulin (IN-105) in Type 1 Diabetes Patients

Start date: August 21, 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to see whether IN-105 (oral insulin) is able to control increase in blood glucose after eating a meal. This study will also tell whether single tablet of IN-105 is safe for patients with Type 1 diabetes mellitus who are currently taking insulin injections.

NCT ID: NCT01032915 Terminated - Clinical trials for Non-infectious Uveitis

Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis

ENDURE
Start date: February 2010
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of AIN457 as adjunctive therapy for the treatment of intermediate uveitis, posterior uveitis, or panuveitis requiring systemic immunosuppression.

NCT ID: NCT01001637 Terminated - Alzheimer Disease Clinical Trials

Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease

Start date: October 2009
Phase: N/A
Study type: Interventional

Curcumin is shown to impact several different pathways of neuroprotection, however clinical trials have not shown positive results, due to the poor bioavailability of curcumin. This study is designed to determine efficacy and safety of high-bioavailability curcumin formulation (Longvida) in subjects with Alzheimer's disease.

NCT ID: NCT00998686 Terminated - Clinical trials for Type 2 Diabetes Mellitus

Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Start date: November 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the safety and tolerability of dutogliptin over 52 weeks.

NCT ID: NCT00976430 Terminated - Parkinson's Disease Clinical Trials

Autologous Mesenchymal Stem Cell Transplant for Parkinson's Disease

Start date: July 2009
Phase: N/A
Study type: Interventional

This study is intended to look at the safety and efficacy of the use of autologous bone marrow derived stem cell transplant in patients with advanced Parkinson's disease.