Clinical Trials Logo

Filter by:
NCT ID: NCT03738514 Completed - Clinical trials for Dentinal Hypersensitivity

Comparison of Efficacy of 5% Fluorocalcium Phosphosilicate Dentifrice and Potassium Nitrate Dentifrice on Dentinal Hypersensitivity

Start date: December 22, 2017
Phase: Phase 2
Study type: Interventional

Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo over a period of 6 weeks.

NCT ID: NCT03733925 Not yet recruiting - Clinical trials for Arthritis, Psoriatic

A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis

Start date: November 30, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the safety of subcutaneous (SC) golimumab in participants with active Ankylosing Spondylitis (AS) or Psoriatic Arthritis (PsA) over 24 weeks.

NCT ID: NCT03733236 Completed - Clinical trials for Ischemic Stricture of Intestine

Safety and Effectiveness Evaluation of the ISS System in Treatment of Acute Ischemic Stroke

ImpACT-1
Start date: July 6, 2006
Phase: N/A
Study type: Interventional

The primary objective of this pilot study is the assessment of the safety of the ISS500 System in patients who have experienced an acute ischemic stroke within the anterior circulation. The secondary objectives of this study are to examine the effectiveness of the ISS500 System implantation in the treatment of acute ischemic stroke.

NCT ID: NCT03730493 Not yet recruiting - Clinical trials for Inpatient Facililty Diagnoses

Effectiveness of a Pictorial Flashcard Regarding Self-care of Peripheral IV Cannula (PIVC) on Its Indwelling Time and Related Complications Among Inpatients

Start date: November 5, 2018
Phase: N/A
Study type: Interventional

The study title is "A Study to evaluate the Effectiveness of a Pictorial Flashcard regarding Self-Care of Peripheral IV Cannula (PIVC) on its indwelling time and related complications among inpatients at ILBS, New Delhi." and it aim to evaluate the Effectiveness of a Pictorial Flashcard regarding Self-Care of PIVC on its indwelling time and related complications among inpatients. Hypotheses All hypotheses will be tested at 0.05 level of significance: H1: There will be a significant difference in indwelling time of PIVC between patients of comparison and experimental group. H2:There will be a significant difference in the occurrence of PIVC related complications between patients of comparison and experimental group. H3: There will be a significant association of theindwelling time of PIVC with the selected demographic and clinical variables. H4: There will be a significant association of the PIVC related complication with the selected demographic and clinical variables. Patients information sheet, Informed consent form & Intervention (Pictorial Flashcard on self-care of PIVC) will be available in both English and Hindi languages •Language difficulty level in Tool/ Scales will be of 8the grader level and will be done by experts.

NCT ID: NCT03727243 Not yet recruiting - Sepsis Clinical Trials

Molecular Diagnosis and Risk Stratification of Sepsis in India

MARS-India
Start date: November 14, 2018
Phase:
Study type: Observational

Background: Globally, sepsis is common with an estimated population incidence of 437 cases per 100, 000 person-years and acute mortality of 26%, one of the few major medical conditions whose incidence and resulting mortality continues to rise. However, true burden is likely significantly higher as a recent meta- analysis could find no data from LMIC where 87% of the world's population resides. Objective: Generate new knowledge that will eventually provide rapid and accurate information about an individual patient suffering from sepsis (or critical illness), including which type of microorganism is responsible for the infection and the severity and stage of the patient's immune response. Methods: MARS-India will be a prospective longitudinal, single-centre observational study, conducted in mixed ICU's of a >2000 bedded tertiary teaching hospital in Manipal, India. The investigators will recruit to three groups- sex and age-matched healthy volunteers (n=150) and patients diagnosed with sepsis/septic shock or non-infectious ICU admissions such as severe trauma, severe burns and patients admitted to ICU after major surgery (n=400). The investigators have optimised a workflow to follow and describe the immunoinflammatory status of septic patients (as well as severe trauma/burn and major surgery) during the first 6 months after their initial injury. At fixed time points the investigators will collect blood in PaxGene, heparin, citrate and EDTA tubes in addition to routine bloods and microbiological samples. Rectal swabs and stool will also be taken for microbiome analysis. Immune functional tests will be performed to determine whole-blood cytokine/chemokine production in response to ex-vivo stimulation using an 8-panel assay. Additionally, complete immunophenotyping using flow cytometry including HLA-DR expression and lymphocyte subsets will be obtained.

NCT ID: NCT03727126 Not yet recruiting - Esophageal Cancer Clinical Trials

Robotic Versus Thoracolaparoscopic Esophagectomy for Esophageal Cancer

Start date: November 2018
Phase: N/A
Study type: Interventional

Esophageal cancer is a debilitating condition. The treatment involved is complex requiring a combination of chemotherapy and surgery in most cases. Complete removal of the tumor and the adjacent lymph nodes is of utmost importance in improving the survival. Lymph node yield following surgery helps in proper staging of the disease and is an important prognosticating variable. It is hypothesized that the lymph node yield following robotic esophagectomy is higher than that following thoracolaparoscopic esophagectomy. The study aims to compare the short term oncological outcomes following robotic esophagectomy and thoracolaparoscopic esophagectomy for carcinoma esophagus.

NCT ID: NCT03727035 Recruiting - Clinical trials for Periodontal Diseases

Quantification of CD163 Inflammatory Biomarker in Chronic Periodontitis and Diabetic Subjects

Start date: February 10, 2018
Phase:
Study type: Observational

The quantification of CD163 will be analysed in the subgingival plaque samples of generalized chronic periodontitis patients with and without diabetes mellitus. The demographic and the periodontal parameters were assessed and the correlated with the quantification of the CD163. The CD163 gene expression was analyzed with RTPCR and the quantification of CD163 will be done using ELISA.

NCT ID: NCT03724513 Completed - Gastric Perforation Clinical Trials

High Altitude Area- A Risk Factor For Gastric Perforation?

Start date: September 15, 2018
Phase:
Study type: Observational

This is an original case series on soldiers evacuated from HAA(High Altitude Area) over last one year(Sept 2017- Aug 2018) , of which 100% cases were found to have gastric antrum perforation. This is a deviation from the usual trend that is being noted in Indian subcontinent where duodenal perforations are commonest.

NCT ID: NCT03722732 Recruiting - Clinical trials for Periampullary Carcinoma

Comparison of Blood Loss in Laparoscopic vs Open Pancreaticoduodenectomy in Patients With Periampullary Carcinoma

Start date: September 11, 2018
Phase: N/A
Study type: Interventional

the study is designed to compare the blood loss between laparoscopic vs open pancreaticoduodenectomy in a randomized clinical trial

NCT ID: NCT03721159 Completed - Coronary Disease Clinical Trials

Quantification of Micro-RNA 146-a in Chronic Periodontitis and Coronary Heart Disease Subjects

Start date: October 1, 2017
Phase:
Study type: Observational

The expression and quantification of Micro-RNA 146-a, was analyzed in the subgingival plaque samples of generalized chronic periodontitis patients with and without coronary heart disease. The demographic variables and periodontal parameters were assessed and correlated with expression of micro-RNA 146-a. The quantification of levels of micro-RNA 146-a was done using Real time Polymerase chain reaction. ( RT-PCR)