Clinical Trials Logo

Filter by:
NCT ID: NCT06187779 Active, not recruiting - Clinical trials for Induction of Labor Affected Fetus / Newborn

Induction ATAD Catheter and Lower Segment Thickness

Start date: December 6, 2023
Phase: N/A
Study type: Interventional

A prospective cohort study of pregnant women undergoing induction of labor at term .inculding- Women with a singleton pregnancy at ≥ 37 weeks' gestation, with a live fetus in cephalic presentation. all women will undergo transvaginal ultrasound assessment before induction of labor admission. Maternal and obstetric characteristics and Bishop score will be recorded. The main outcome is the overall rate of Cesarean delivery after induction of labor.

NCT ID: NCT06163898 Active, not recruiting - Multiple Myeloma Clinical Trials

A Study to Evaluate Alnuctamab in Combination With Mezigdomide in Participants With Relapsed and/or Refractory Multiple Myeloma

Start date: February 27, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the recommended dose and schedule, and evaluate the safety and preliminary efficacy of alnuctamab in combination with mezigdomide in participants with relapsed and/or refractory multiple myeloma.

NCT ID: NCT06156722 Active, not recruiting - Fertility Issues Clinical Trials

The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes. The methods include the selection of the optimal spermatozoa based on its morphology by IMSI, together with its physiological function of binding to HA by Spermslow (SS). The current study compared a group of ET after sperm selection by IMSI with SS to a group of ET after sperm selection by IMSI-only without SS, and to a mixed ET group where two embryos were transferred, one after IMSI-only and the other one after IMSI with SS.

NCT ID: NCT06153966 Active, not recruiting - Prion Disease Clinical Trials

PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717.

Start date: January 4, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of intrathecal (IT) delivery of ION717.

NCT ID: NCT06115980 Active, not recruiting - Bradycardia Clinical Trials

Safety and Preliminary Performance of Xtrac O.S. System for Lead Extraction.

XTR
Start date: August 27, 2023
Phase: N/A
Study type: Interventional

This is an open label, interventional, feasibility, prospective, multicenter, clinical trial of lead extraction. The Xtrac O.S. system is intended for transvenous removal of pacing or defibrillator leads, having an inner lumen, through a superior approach. A total of 15 patients, who are scheduled for CIED lead extraction, will be recruited in order to ensure a total of at least 10 patients finishing the study procedures and follow up.

NCT ID: NCT06045507 Active, not recruiting - HIV Clinical Trials

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

Start date: November 8, 2023
Phase: Phase 2
Study type: Interventional

This double-blind, placebo-controlled study is designed to assess the safety, tolerability, and pharmacokinetics of oral MK-8527 taken once monthly (QM) in participants at low risk for human immunodeficiency virus Type 1 (HIV-1) infection.

NCT ID: NCT06013696 Active, not recruiting - Ulcerative Colitis Clinical Trials

Bleach and Urine Color in UC Patients Using 5ASA

Asableach
Start date: July 16, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA

NCT ID: NCT06003530 Active, not recruiting - Diabetic Foot Ulcer Clinical Trials

Study for Treatment of Chronic Diabetic Foot Ulcers With the Investigational Allogeneic Cell Therapy Product, hOMSC200

Start date: January 6, 2022
Phase: Phase 1
Study type: Interventional

Purpose of this phase 1/2a study is to assess the safety and efficacy of administration of allogeneic human oral mucosal stem cells (hOMSCs) in patients suffering from chronic diabetic foot ulcers (DFU).

NCT ID: NCT05965167 Active, not recruiting - Hypoparathyroidism Clinical Trials

Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo

Start date: May 11, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to characterize and compare the pharmacokinetics of hPTH(1 34) after treatment with a modified oral formulation (EBP11 and EBP22) versus two dose levels of Entera Bio's extensively studied oral EBP05 1.5 mg and 2.5 mg as well as the commercial Forteo 0.02 mg subcutaneous injection.

NCT ID: NCT05952869 Active, not recruiting - Clinical trials for Hypercholesterolemia

A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017) CORALreef HeFH

Start date: August 8, 2023
Phase: Phase 3
Study type: Interventional

The goal of this study is to evaluate the efficacy, safety, and tolerability of MK-0616 in adult participants with heterozygous familial hypercholesterolemia. The primary hypothesis is that MK-0616 is superior to placebo on mean percent change from baseline in low-density lipoprotein cholesterol (LDL-C) at Week 24.