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NCT ID: NCT01192295 Completed - Pain Clinical Trials

Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids

Start date: November 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to characterize the safety of oxycodone hydrochloride (HCl) controlled-release (CR) tablets in opioid tolerant pediatric patients aged 6 to 16 years, inclusive, with moderate to severe malignant and/or nonmalignant pain requiring opioid therapy.

NCT ID: NCT01192217 Completed - Pneumothorax Clinical Trials

Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax

Start date: January 2006
Phase: N/A
Study type: Interventional

The investigators conducted a prospective randomized study to compare axillary minithoracotomy versus a modified two-port thoracoscopic technique for surgical pleurodesis in patients with recurrent spontaneous pneumothorax operated in a single institution. The main objective of the study was to investigate possible differences regarding short- and long-term clinical outcome between the two different techniques.

NCT ID: NCT01191268 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study in Participants With Type 2 Diabetes Mellitus (AWARD-4)

Start date: November 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of LY2189265 in comparison to Insulin Glargine, both in combination with Insulin Lispro (plus or minus Metformin), in participants with Type 2 Diabetes treated with 1 or 2 injections of insulin.

NCT ID: NCT01191086 Completed - Epilepsy Clinical Trials

Open-label Extension Study to Evaluate the Safety of USL255 in Patients With Refractory Partial-onset Seizures

Start date: October 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the safety of USL255 as adjunctive therapy in patients with refractory partial onset-seizures.

NCT ID: NCT01186939 Completed - Clinical trials for Myelodysplastic Syndromes

An Extension to Study AZA PH GL 2003 CL 001 Allowing for Continuation of Azacitidine Treatment in Patients With Myelodysplastic Syndromes (MDS)

Start date: April 1, 2007
Phase: Phase 3
Study type: Interventional

At the conclusion of study AZA PH GL 2003 CL 001 (NCT00071799), eligible participants could be enrolled in an optional extension phase in order to continue treatment with azacitidine until it became commercially available; the continued treatment was for ethical and safety reasons only and not to provide additional efficacy data.

NCT ID: NCT01186744 Completed - Psoriasis Clinical Trials

A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The primary objectives of the study are to 1) compare the efficacy responses of CP 690,550 (5 mg BID and 10 mg BID) versus placebo following 24 weeks of CP 690,550 treatment and subsequent withdrawal of active treatment at various timepoints during the 16 week double blind active or placebo treatment period; 2) evaluate the regain of efficacy responses of CP 690,550 (5 mg BID and 10 mg BID) following 4 -16 weeks of CP 690,550 treatment withdrawal and subsequent re treatment; and 3) evaluate the safety and tolerability of CP 690,550 (5 mg BID and 10 mg BID) in subjects with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy or phototherapy.

NCT ID: NCT01185457 Completed - Clinical trials for Autonomic Nervous System

Effect of Interscalene Block on Heart Rate Variability (HRV)

Start date: June 2010
Phase: N/A
Study type: Observational

The Left interscalene block has a different effect on heart's autonomic nervous system, as measured with Heart Rate Variability, compared to Right interscalene block

NCT ID: NCT01183780 Completed - Colorectal Cancer Clinical Trials

A Study in Second Line Metastatic Colorectal Cancer

Start date: December 2, 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare overall survival in participants with metastatic colorectal cancer treated with either ramucirumab and FOLFIRI or placebo and FOLFIRI.

NCT ID: NCT01179048 Completed - Clinical trials for Diabetes Mellitus, Type 2

Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results

LEADER®
Start date: August 31, 2010
Phase: Phase 3
Study type: Interventional

This trial is conducted in Africa, Asia, Europe, and North and South America. The aim of this trial is to determine the long term effect of liraglutide on cardiovascular events in subjects with type 2 diabetes.

NCT ID: NCT01178996 Completed - Chronic Hepatitis C Clinical Trials

Thymosin Alpha-1 in Combination With Peg-Interferon Alfa- 2a and Ribavirin for the Therapy of Chronic Hepatitis C Nonresponsive to the Combination of IFN and Ribavirin.

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study was to determine safety and efficacy of 48 weeks treatment with Thymosin alpha 1 (Talpha1) in combination with pegylated interferon (PEGIFN) alpha2a and ribavirin (RBV) in adult patients with chronic hepatitis C (CHC) already treated with, and not responding to previous courses of PEGIFN alpha plus RBV combination therapy, in comparison with a concurrent group treated with PEG IFN alpha2a in combination with RBV and placebo.