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NCT ID: NCT00529126 Completed - Postoperative Pain Clinical Trials

Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy

Start date: September 2007
Phase: Phase 2
Study type: Interventional

Phase 2 study to evaluate three dose levels of SKY0402 compared with 75 mg of bupivacaine HCl.

NCT ID: NCT00525577 Active, not recruiting - Diabetes Clinical Trials

ANDES-AGI-1067 as a Novel Antidiabetic Agent Evaluation Study

ANDES
Start date: August 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This double-blind, placebo-controlled, dose-finding study is designed to identify the lowest AGI-1067 dose that improves glycemic control as measured by HbA1c and fasting glucose in subjects with Type 2 diabetes mellitus. Glycemic control will be measured during a 6-month treatment period in subjects who are on 1 or no antidiabetic drugs

NCT ID: NCT00525213 Completed - Clinical trials for Rheumatoid Arthritis

Study to Evaluate the Efficacy and Safety of Orally Administered Rob 803 When Added to Methotrexate

ROBUST
Start date: October 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the efficacy (ACR20) of Rob 803 administered orally once daily for 12 weeks in combination with a stable dose of methotrexate in subjects with moderate or severe active RA.

NCT ID: NCT00509145 Completed - Multiple Sclerosis Clinical Trials

Safety and Efficacy of Orally Administered Laquinimod Versus Placebo for Treatment of Relapsing Remitting Multiple Sclerosis (RRMS)

ALLEGRO
Start date: November 13, 2007
Phase: Phase 3
Study type: Interventional

Determination the efficacy of daily oral treatment with laquinimod 0.6 mg capsules as compared to placebo in subjects with Relapsing Remitting Multiple Sclerosis (RRMS).

NCT ID: NCT00482209 Completed - Induced Abortion Clinical Trials

Study of 400mcg Versus 800mcg Buccal Misoprostol Following Mifepristone 200mg for Abortion up to 63 Days Gestation

Start date: May 2007
Phase: N/A
Study type: Interventional

This double-blind, randomized study will compare the efficacy and acceptability of mifepristone 200mg followed in 36-48 hours by 400mcg or 800mcg of buccal misoprostol (i.e., in the cheeks) for termination of pregnancy in women up to 63 days LMP.

NCT ID: NCT00481936 Terminated - Clinical trials for Neoplasms, Glandular and Epithelial

Study of the Safety of VB6-845 in Patients With Advanced Solid Tumours of Epithelial Origin

Start date: May 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the maximum tolerated dose (MTD) of VB6-845 and to evaluate the safety and tolerability of VB6-845 when administered as a monotherapy IV infusion to patients with advanced solid tumour of epithelial origin.

NCT ID: NCT00462761 Completed - Leukemia Clinical Trials

A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status

Start date: January 2007
Phase: Phase 1
Study type: Interventional

Patients received oral AC220 daily for 14 days to study the side effects, tolerability and best dose for treating relapsed or refractory acute myeloid leukemia, regardless of FLT3 status.

NCT ID: NCT00431561 Completed - Glioblastoma Clinical Trials

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Start date: April 2003
Phase: Phase 2
Study type: Interventional

In this multinational dose finding Phase IIb study the efficacy and safety of two doses of AP 12009 compared to standard chemotherapy (temozolomide or PCV) is investigated in adult patients with confirmed recurrent high-grade glioma.

NCT ID: NCT00414583 Completed - Clinical trials for Cerebrovascular Accident

Stroke in Young Fabry Patients (sifap1): Frequency of Fabry Disease in Young Stroke Patients

sifap1
Start date: January 2008
Phase:
Study type: Observational

More than one million people in Europe suffer from a stroke every day. Normally older people have a stroke, but also a significant number of younger people between 18 and 55 years. Usually, these cannot be explained by the classical risk factors such as diabetes, overweight and high blood pressure. New studies indicate that in about 1 - 2 % of the younger stroke patients the cause could have been an undiagnosed genetic disease, the so called Fabry disease. The purpose of this study is to determine in a large number of young stroke patients, how many strokes were caused by Fabry Disease.

NCT ID: NCT00413595 Completed - Clinical trials for Cerebrovascular Accident

Stroke in Young Fabry Patients (sifap2): Characterization of the Stroke Rehabilitation

sifap2
Start date: July 2007
Phase:
Study type: Observational

New studies indicate that in about 1 - 2 percent of the younger stroke patients the cause could have been an undiagnosed genetic disease, the so called Fabry disease. In this case certain fat molecules are not digested and broken down by the body - but remain in the cells. These fat molecules build up to dangerous levels, which start to damage the body, because they accumulate e.g. in the walls of the blood vessels. This accumulation in the blood vessels of the whole body may cause life-threatening malfunctions in the brain, inducing a stroke. The purpose of this study is to investigate the stroke rehabilitation of Fabry patients during different therapeutic standard approaches for stroke and for Fabry disease (if any). During this study, stroke patients with Fabry disease will be monitored in greater detail to determine whether the differences in treatment are significant for patient recovery and on what they depend.