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NCT ID: NCT05955001 Active, not recruiting - Clinical trials for Erectile Dysfunction

Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate

Start date: April 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

From previous studies, the investigators found that sexual outcomes after prostate surgery may show insignificant improvement, remain unchanged or deteriorate in non-negligible number of patients especially those with high preoperative IIEF scores. Deterioration of erectile function could be attributed to persistence of storage symptoms specially nocturia. Several pathophysiologic mechanisms, described before, are involved in pathogenesis of LUTS and ED and one can imagine that after relief of obstruction, the erectile function should improve, however lack of improvement or even deterioration suggests that damage associated with these mechanisms is irreversible and patients may require some sort of penile rehabilitation after surgery. The investigators hypothesized that Tadalafil may enhance relief of storage symptoms and enhance recovery of erectile function after surgery for BPH. With this assumption, a RCT was designed to examine the utility and efficacy of Tadalafil, once daily dose, to relieve persistent/ de novo storage symptoms and early erectile function deterioration after endoscopic prostate surgery.

NCT ID: NCT05947331 Active, not recruiting - Clinical trials for Infantile Nystagmus Syndrome

Correction of Head Turn in Idiopathic Infantile Nystagmus

Start date: April 5, 2022
Phase: N/A
Study type: Interventional

Infantile nystagmus is involuntary, bilateral, conjugate and rhythmic oscillations of the eyes which may present at birth or develop within the first 6 months of life. It may be idiopathic appearing without visual or neurological impairment or may be secondary to an afferent visual defect such as foveal hypoplasia, congenital cataract, retinal dystrophy or optic atrophy. Aiming at improving outcome of head turn in idiopathic infantile nystagmus, comparison between the efficacy and safety of graded Anderson procedure and Kestenbaum procedure is essential.

NCT ID: NCT05937100 Active, not recruiting - Clinical trials for Carious Exposure of Pulp

New Vital Pulpotomy Medications in Primary Molars

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

Evaluate clinically and radiographically the effect of biodentine and hyaluronic acid (HA) versus formocresol (FC) as pulpotomy medications in primary molars.

NCT ID: NCT05932940 Active, not recruiting - Angle Glaucoma Open Clinical Trials

Incidence of Descemet Membrane Detachment Post GATT by AS OCT

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

detection of Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

NCT ID: NCT05921500 Active, not recruiting - Dental Trauma Clinical Trials

Clinical and Radiographic Evaluation of Intra Coronal Bleaching of Primary Anterior Teeth

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

clinical and radiographic evaluation the intracoronal bleaching of primary anterior teeth using sodium perborate with walking bleach technique

NCT ID: NCT05918497 Active, not recruiting - Clinical trials for Different Regimens in Treatment of Hypothyroidism During Fasting in Ramadan

Comparison Between Variable Time Regimen of Dosing L-Thyroxine for Treatment Hypothyroid Fasting Ramadan

Start date: April 25, 2023
Phase:
Study type: Observational

This is a study aiming to report the effect of a variable time regimen of L T4 during Ramadan, as an easier alternative, on adherence and thyroid status after Ramadan compared to standard daily dosing.

NCT ID: NCT05912907 Active, not recruiting - Clinical trials for Pulp Disease, Dental

Potassium Nitrate in Polycarboxylate as a Direct Pulp Capping

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The study aimed to compare potassium nitrate in polycarboxylate cement to mineral trioxide aggregate as a direct pulp capping material of young permanent teeth in patients from 7 to 10 ears

NCT ID: NCT05905692 Active, not recruiting - Clinical trials for Intradialytic Hypotension

Evaluation of the Impact of L- Carnitine in Intradialytic Hypotension in Pediatric Patients on Regular Hemodialysis

Start date: May 30, 2023
Phase: Phase 3
Study type: Interventional

Intradialytic hypotension (IDH) is defined as less than the 5th percentile of SBP measurements and is associated with clinical symptoms, such as abdominal pain, nausea, vomiting, muscle cramps, restlessness, light-headedness, syncope, and anxiety. In adults There is no consensus definition of IDH, however, according to the Kidney Disease Outcomes Quality Initiative and European Best Practice Guidelines, IDH is defined as a decline in systolic blood pressure ≥20 mmHg or a decrease in a mean arterial pressure by 10 mmHg and associated with clinical events like abdominal pain, nausea, vomiting, muscle cramps, dizziness, fatigue, and restlessness. IDH occurs in response to the reduction in blood volume (BV) during ultrafiltration (UF) and subsequent poor compensatory mechanisms due to abnormal cardiac function (left ventricular dysfunction, chamber remodeling, congenital heart diseases, and arrhythmias) or autonomic or baroreceptor failure. To maintain volume status, the body shifts fluid from the interstitial space to the intravascular space and increases heart rate, contractility, and vascular tone. Plasma refilling, another essential factor in maintaining euvolemia, depends on oncotic, osmotic, and hydraulic gradients across vascular beds. If UF rates surpass plasma refilling rates, intravascular volume falls and hypotension results. Hematocrit levels, tissue hydration and arterial vasoconstriction all promote plasma refilling rates. Alterations in these factors during dialysis decrease the plasma refilling rate, resulting in hypotension. Aim of The Work: The aim of this study is to assess and evaluate the efficacy and safety of L Carnitine in the prevention of intradialytic hypotension in pediatric patients on regular hemodialysis.

NCT ID: NCT05902975 Active, not recruiting - Clinical trials for Dental Caries in Children

Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles

Start date: May 21, 2022
Phase: N/A
Study type: Interventional

Fiber reinforced composite resin space maintainer

NCT ID: NCT05900492 Active, not recruiting - Cesarean Section Clinical Trials

Incidence of Uterine Cesarean Scar Niche After Cesarean Delivery

Start date: January 1, 2023
Phase:
Study type: Observational

To assess the incidence of cesarean scar niche and its risk factors in a prospectively collected population.