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NCT ID: NCT06463964 Enrolling by invitation - Acute Kidney Injury Clinical Trials

Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency

Start date: June 1, 2024
Phase:
Study type: Observational

Acute Decompensated Heart Failure ADHF is one of the leading causes of hospitalization. ADHF is a growing global health problem affecting more than 26 million individuals worldwide Acute Kidney Injury AKI is a common event in the natural disease history of patients with Heart Failure HF, The clinical importance of the co-existence of acute cardiac and renal dysfunction, known as acute cardiorenal syndrome CRS, and its management have recieved great attention recently Various studies have employed different criteria to define and calssify AKI. According to Risk, Injury, and Failure; and Loss, and End-stage kidney disease RIFLE criteria formulated by the Acute Dialyisis Quality Initiative ADQI AKI can be divided into five stages; renal injury risk, renal impairment, renal failure, renal function loss, and end stage kidney disease

NCT ID: NCT06439147 Enrolling by invitation - Clinical trials for Developmental Dysplasia of the Hip

Comparison Between Two Techniques of Capsulotomy During Capsulorrhaphy in Cases of Developmental Dysplasia of the Hip

Start date: October 11, 2023
Phase: N/A
Study type: Interventional

comparison of the outcome between using U-shaped incision and T-shaped incision for capsulorrhaphy in management of Developmental dysplasia of the hip

NCT ID: NCT06433141 Enrolling by invitation - Primary Teeth Clinical Trials

Evaluation of Bioflex Crowns Endocrowns Compared to Ready-Made Zirconia Crowns on Pulpotomized Primary Molars

Start date: December 19, 2023
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate clinical performance, parent's satisfaction, gingival health and bacterial effects of Bioflex crowns &Endocrowns compared to ready-made zirconia Crowns on Pulpotomized primary molars

NCT ID: NCT06421883 Enrolling by invitation - Clinical trials for End Stage Renal Disease

Study the Effect of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Level in Hemodialysis Patients

probiotic
Start date: March 15, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to learn if probiotic has an effect on Trimethylamine-N-Oxide Plasma Level in plasma, which represent strong risk factor for Atherosclerosis in end stage renal disease patients who undergoing hemodialysis the main questions to answer are : Does probiotic lower Trimethylamine-N-Oxide concentration? does probiotic participating in decreasing risk of atherosclerosis in end stage renal disease patients undergoing hemodialysis ? research will compare between patients who are taking probiotic and control group (taking no drug) participants will take probiotic for 3 months visit the clinic once every 2 weeks for checkups and tests All Patients will be subjected to the following: 1. Informed consent. 2. Demographics and history taking: Using Patient Data sheet. 3. Laboratory evaluation including: Kidney function tests: blood urea,serum creatinine, albumin ,uric acid. Complete blood count (CBC). C-reactive protein (CRP).

NCT ID: NCT06412445 Enrolling by invitation - Inguinal Hernia Clinical Trials

Self-Fixating Mesh Versus Mesh Fixation With Tissue Glue in Laparoscopic Inguinal Hernia Repair

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

The main objective of this study is to compare between the safety and efficacy of self-fixating mesh versus mesh fixation with tissue glue in patients undergoing laparoscopic transabdominal inguinal hernia repair (TAPP). The criteria of comparison shall include operating time, post-operative pain and recurrence.

NCT ID: NCT06406140 Enrolling by invitation - Clinical trials for End-stage Renal Disease

Study the Effect of Niacin on Lipoprotein (a) Concentration and Hyperphosphatemia in Hemodialysis Patients

Start date: March 15, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to learn if Niacin has an effect on lipoprotein (a) concentration and hyperphosphatemia, which represent strong risk factors for cardiovascular diseases, in End-stage renal disease (ESRD) patients undergoing hemodialysis. It will also learn about the safety of Niacin. The main questions it aims to answer are: - Does Niacin lower lipoprotein (a) concentration? - Does Niacin treat hyperphosphatemia in End-stage renal disease (ESRD) patients undergoing hemodialysis? Researchers will compare Niacin to a control group (taking no drug) to see if drug Niacin works to treat hyperphosphatemia and lower lipoprotein (a) concentration. Participants will: - Take drug Niacin or no drug every day for 3 months - Visit the clinic once every 2 weeks for checkups and tests All Patients will be subjected to the following: 1. Informed consent. 2. Demographics and history taking: Using Patient Data sheet. 3. Laboratory evaluation including: Kidney function tests: blood urea,serum creatinine, albumin ,uric acid. Complete blood count (CBC). Lipid profile:Lipoprotein (a),total cholesterol,triglyceride,high density lipoprotein (HDL), low density lipoprotein (LDL). Phosphorous, calcium, sodium, parathyroid hormone (PTH), alkaline phosphatase (ALP). C-reactive protein (CRP).

NCT ID: NCT06403683 Enrolling by invitation - Clinical trials for Primary Dysmenorrhea

Physical Activity Level and Insomnia

Start date: January 30, 2024
Phase:
Study type: Observational [Patient Registry]

This study aims to investigate the relationship between physical activity levels and insomnia in females with primary dysmenorrhea.

NCT ID: NCT06395818 Enrolling by invitation - Clinical trials for Atrophy of Edentulous Alveolar Ridge

the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation

Start date: March 29, 2023
Phase: N/A
Study type: Interventional

Each patient will receive 2 prefabricated CAD-CAM allogeneic bone blocks sterilized with gamma rays with different rehydration methods. Side I: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid * Side II: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution Both blocks are fixed with osteosynthesis screws, covered with non resorbable membranes** The membranes will be removed after 5 months, dental implants will be placed and core biopsy will be collected from the site of the implant placement for histologic evaluation

NCT ID: NCT06380946 Enrolling by invitation - Clinical trials for Effect of Platelet Rich FibrinDuring Clear Aligner Therapy

Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The aim of this prospective clinical project will be to assess the effect of platelet rich fibrin on the rate of different orthodontic tooth movements during clear aligner therapy.

NCT ID: NCT06357338 Enrolling by invitation - Clinical trials for Invasive Breast Cancer

Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma

Start date: March 19, 2024
Phase:
Study type: Observational

Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma