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NCT ID: NCT06004453 Recruiting - Heart Failure Clinical Trials

Characterizing Guideline Adoption and Treatment Quality in Clinical Routine of German HFrEF Care

CONNECT
Start date: April 4, 2023
Phase:
Study type: Observational

This is a multicenter, non-randomized, non-interventional cohort study with prospective and retrospective collection of primary data on heart failure with reduced ejection fraction (HFrEF) patient treatment and care following a decompensation event in different types of Heart Failure Unit (HFU) or non-HFU centers across Germany.

NCT ID: NCT06004362 Recruiting - Post-COVID Syndrome Clinical Trials

Complementary and Integrative Medicine as an Online Intervention in Patients With Post-covid Syndrome After COVID-19

Start date: September 4, 2023
Phase: N/A
Study type: Interventional

The Post-COVID syndrome is a COVID-19 sequelae disease with high individual burden. We conduct a prospective, two-arm, randomized-controlled intervention study with embedded qualitative and physiological sub-studies in a mixed-methods design.

NCT ID: NCT06003426 Recruiting - Clinical trials for Idiopathic Pulmonary Fibrosis

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

Start date: September 14, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986278 in participants with Idiopathic Pulmonary Fibrosis.

NCT ID: NCT06002802 Completed - Clinical trials for Epstein-Barr Virus Infections

Study on Infectious Mononucleosis in Munich

IMMUC
Start date: March 1, 2016
Phase:
Study type: Observational

This observational clinical study aims at the identification of novel biomarkers and causative factors of complicated and/or protracted Epstein-Barr virus-associated infectious mononucleosis (IM). Clinical, biochemical, and routine virological data were collected from 200 patients with IM, novel analytical tools were implemented, and immunological and virological experimental data were generated using blood samples and mouthwashes. Patients have been investigated within four weeks after the onset of symptoms as well as one month and six months thereafter.

NCT ID: NCT06002425 Recruiting - Clinical trials for Gastrointestinal Neoplasm Malignant

Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models

Start date: August 29, 2023
Phase: N/A
Study type: Interventional

This study will evaluate the utility of ChatGPT in recommending treatment plans for patients with gastrointestinal cancers, using both retrospective and prospective data.

NCT ID: NCT06001177 Recruiting - Celiac Disease Clinical Trials

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

SynCeD
Start date: December 13, 2023
Phase: Phase 2
Study type: Interventional

The study goal is to evaluate the efficacy, safety, and tolerability of KAN-101 in participants with Celiac Disease (CeD)

NCT ID: NCT06000891 Recruiting - Clinical trials for Safety and Tolerability

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Start date: September 15, 2023
Phase: Phase 1
Study type: Interventional

The trial is a Phase 1, single-centre, randomised and double-blind within cohorts, placebo-controlled, sequential multiple ascending dose trial including three cohorts in Part 1 in a semi-parallel design and one cohort in Part 2 in overweight and obese but otherwise healthy subjects, randomised to ZP7570 or placebo within each cohort where the observational period is 18 weeks. All subjects will be dosed for 13 weeks with ascending weekly doses of ZP7570 at dose levels with corresponding volume of placebo.

NCT ID: NCT05999994 Recruiting - Neoplasms Clinical Trials

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

CAMPFIRE
Start date: January 22, 2020
Phase: Phase 2
Study type: Interventional

The main purpose of the master is to help the research sites and sponsor carry out several clinical trials more efficiently by providing a common research protocol. Individual clinical trials under this master protocol define drug/disease-specific research goals and activities to test them. New studies will be added as new drugs emerge against different cancers. Participation in the trial will depend on how long the benefit lasts.

NCT ID: NCT05999968 Active, not recruiting - Prostatic Neoplasms Clinical Trials

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

Start date: January 12, 2024
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to learn more about the safety and tolerability of abemaciclib when given in combination with darolutamide to participants with prostate cancer that has spread after initial treatment. Participation may last up to 32 months.

NCT ID: NCT05999799 Recruiting - Dermatitis, Atopic Clinical Trials

A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis

Start date: November 16, 2023
Phase: Phase 2
Study type: Interventional

This study is parallel group, placebo-controlled dose-ranging study to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of GSK1070806 in adult participants with moderate to severe Atopic Dermatitis (AtD), who have previously been treated with medicated topical treatments or a biologic therapy.