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NCT ID: NCT05199493 Completed - Cardiac Surgery Clinical Trials

Reducing Acute Kidney Injury Occurence by Administering Angiotensin II

AIDED
Start date: December 27, 2021
Phase: Phase 3
Study type: Interventional

The aim of this study is to evaluate whether adding angiotensin II to the standard of care is superior compared to the standard of care alone with respect to kidney damage (personalized approach) after cardiac surgery.

NCT ID: NCT05195567 Completed - Diabetes Mellitus Clinical Trials

System Accuracy of a Blood Glucose Monitoring System GlucoSpark/GlucoScore

Start date: February 17, 2022
Phase: N/A
Study type: Interventional

This study assesses the system accuracy a blood glucose monitoring systems pursuant to ISO 15197

NCT ID: NCT05195372 Completed - Clinical trials for Venous Thromboembolism

Effectivity and Safety of Different Anticoagulants in Patients With Thromboembolic Antiphospholipid Syndrome

Start date: January 1, 2015
Phase:
Study type: Observational

Retrospective monocentric registry to evaluate the efficacy and safety of different anticoagulants in patients with thromboembolic antiphospholipid syndrome

NCT ID: NCT05194124 Completed - Clinical trials for Bardet-Biedl Syndrome

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Start date: December 21, 2021
Phase: Phase 3
Study type: Interventional

A trial to compare the weekly and daily formulations of setmelanotide in patients with genetic defects in the melanocortin-4 receptor pathway.

NCT ID: NCT05192902 Completed - Pain Perception Clinical Trials

Pain Perception Following Computer-Controlled vs. Conventional Dental Anesthesia

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This single-blind two-arm randomized control trial (RCT) aims to evaluate the pain perception during and following administration of dental local anaesthesia using two different systems; i.e. computer-controlled (CCLA) and conventional.

NCT ID: NCT05190419 Completed - Psoriasis Clinical Trials

Study to Assess the Efficacy and Safety of Orismilast in Psoriasis

IASOS
Start date: December 30, 2021
Phase: Phase 2
Study type: Interventional

This study investigates 3 different doses of orismilast modified release compared to placebo in adult patients with moderate-to-severe plaque-type psoriasis. The purpose of the study is to assess the effect of orismilast modified release in moderate-to-severe plaque-type psoriasis and assess the safety aspects of these 3 different doses.The patients will receive an oral treatment of either orismilast modified release tablets or placebo tablets 2 times a day for 16 weeks.

NCT ID: NCT05190367 Completed - Chronic Pain Clinical Trials

Influence of Trauma on Pain Area and Widespreadness in Chronic Pain Patients

Start date: February 28, 2019
Phase:
Study type: Observational

It is well known that patients suffering from chronic pain report higher levels of pain, anxiety, and depression if they have experienced a traumatic event. However, little is know about pain area and widespreadness. In this retrospective study, we want to investigate whether pain area and widespreadness differs in chronic pain patients with and without traumatic events. To test this hypothesis we will retrospectively analyse pain drawings collected at the pain outpatient department from Hannover Medical School. Participants will be divided into four groups depending on the severity of their traumatic events: no trauma; accidental trauma; interpersonal trauma; post-traumatic stress disorder (PTSD).

NCT ID: NCT05190263 Completed - Solid Tumor Clinical Trials

Quality Assurance on Anemia Management in Patients With Solid Tumors and Malignant Lymphoma

QA Anemia
Start date: October 25, 2021
Phase:
Study type: Observational

The aim of the study is to analyze the implementation of the 2018 updated ESMO Guideline in patients with tumor diseases as well as the corre-sponding recommendations of the Onkopedia Guideline and the S3 Guide-line Supportive Therapy in routine clinical practice in Germany. To this end, a nationwide, representative, retrospective patient documen-tation will be conducted to observe the current practice of anemia man-agement in hospitals and among office-based physicians.

NCT ID: NCT05189574 Completed - Anastomotic Leak Clinical Trials

Endo-Vac-Therapy for Post-Sleeve Gastrectomy Leaks

Start date: January 3, 2020
Phase:
Study type: Observational

Endoscopic negative pressure therapy (ENPT) is a safe technique, showing promising results in the treatment of leakages of the upper and lower gastrointestinal tract. The purpose of this study is to determine the safety and efficacy of ENPT in the management of proximal staple line leak after sleeve gastrectomy.

NCT ID: NCT05189379 Completed - Heavy Drinking Clinical Trials

Targeted Extinction of Drug Cues During Sleep - Olfactory Cue Reactivity Task

TEDDS_OCRT
Start date: March 10, 2022
Phase: N/A
Study type: Interventional

The study aims to utilise olfactory stimulation in addition to the visual stimulation in cue reactivity tasks to enhance precision in measuring alcohol based cues in individuals diagnosed with heavy drinking. The study consists of one cue reactivity task with visual stimuli, another cue reactivity task with matching odour/visual stimuli and lastly a monetary incentive delay task.