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NCT ID: NCT04006171 Completed - Clinical trials for Polycystic Ovary Syndrome

Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy Women

CNP
Start date: July 15, 2019
Phase: N/A
Study type: Interventional

Recent studies have shown that C natriuretic peptide is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors. It is suggested that produced cGMP maintains the transport of oocytes via the gap junctions and leads to a continuous increase in cyclic adenosine monophosphate (cAMP) levels in the oocyte. An important role of increased internal cAMP levels in the oocyte is shown to suppress meiotic progression. Deoxyribonucleic acid studies in animals have shown that expression of the natriuretic peptide precursor increases during the periovulatory period and shows that this increase decreases rapidly after luteinizing hormone / human chorionic gonadotropin (hCG) stimulation.Human studies have shown that after ovulation induction, the CNP level in follicular fluid decreases following ovulatory dose of hCG.Polycystic ovary syndrome (PCOS) is the most common endocrine disease in the reproductive period, characterized by hyperandrogenism, oligo-anovulation, and polycystic ovarian morphology on ultrasonography, and in an animal study investigating the relationship between CNP and PCOS, serum CNP levels were increased in polycystic ovary syndrome.CNP serum level is thought to show differences between healthy women and women with polycystic ovary syndrome.

NCT ID: NCT04000815 Completed - Clinical trials for Healthy Postmenopausal Women

Serum Levels of C Type Natriuretic Peptide in Different Reproductive Periods

CO
Start date: July 24, 2019
Phase: N/A
Study type: Interventional

Recent studies have shown that C natriuretic peptide (CNP) is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.It has been suggested that the transport of cGMP to oocyte via gap junctions causes a continuous increase in cyclic adenosine monophosphate (cAMP) levels within the oocyte. An important role of increased cAMP levels in oocyte is shown to suppress meiotic progression. Deoxyribonucleic acid (DNA) studies in animals have shown that expression of the natriuretic peptide precursor increases during the periovulatory period and shows that this increase decreases rapidly after Luteinizing hormone(LH) / human chorionic(hCG) stimulation. Human studies have shown that after ovulation induction, the CNP level in follicular fluid decreases following ovulatory dose of hCG (9).

NCT ID: NCT03863678 Completed - Stroke Clinical Trials

Effects of Dry Needling on Spasticity, Functions, Balance and Independence Level in Patients With Stroke

Start date: May 12, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of dry needling method in addition to neurodevelopmental therapy on spasticity, upper and lower extremity functions, balance and independence level in patients with stroke who have spasticity.

NCT ID: NCT03856333 Completed - Treatment Clinical Trials

Cognitive Exercise Therapy Approach Scale in Patients With Chronic Neck Pain

Start date: January 31, 2019
Phase: N/A
Study type: Interventional

The aim of this study was to determine the validity, reliability and sensitivity of the Cognitive Exercise Therapy Approach Scale in patients with neck pain.

NCT ID: NCT03816085 Completed - Healthy Clinical Trials

Shoes on Balance, Muscular Endurance and Functional Skills

Start date: December 15, 2018
Phase: N/A
Study type: Interventional

In daily life, stiletto heeled shoes which are popularly preferred by women have different heel heights. This study aims to investigate the effects of these differences on balance, muscular endurance and functional skills. Heel heights were chosen as 4 and 10 cm. Other features of shoes (stiletto type/colour etc.) will be same. The tests will be randomly done barefoot, 10 cm, and 4cm shoes.

NCT ID: NCT03777995 Completed - Child Development Clinical Trials

A New Designed Balance Platform for Children

Start date: December 15, 2018
Phase:
Study type: Observational

People always come across with different floors which gradually affect dynamic balance. Dynamic balance is important in activities of daily life of all people. There are various reliable and valid tests for both children and adults, but no test design which includes different floor materials has been developed. Thus, this study aimed to describe a new designed balance test platform and investigate its reliability and validity in 3-5 years old children.

NCT ID: NCT03728387 Completed - Exercise Clinical Trials

The Validity, Reliability and Responsiveness of the Fullerton Advanced Balance Scale in Osteoarthritis

Start date: February 18, 2019
Phase: N/A
Study type: Interventional

The primary aim of our study is to evaluate the validity and reliability of the Fullerton Advanced Balance (FAB-T) scale in individuals with osteoarthritis. The secondary aim of this study is to evaluate the responsiveness of the FAB-T scale to change in patients with osteoarthritis.

NCT ID: NCT03705910 Completed - Fibromyalgia Clinical Trials

Effects of Mobilization and Perceptive Rehabilitation on Patients With Fibromyalgia Syndrome

Start date: November 6, 2018
Phase: N/A
Study type: Interventional

The aim of our study is to determine and compare the effects of perceptive rehabilitation against other mobilization techniques on the treatment of fibromyalgia symptoms and disability. Participants in this study will be randomly assigned to three separate groups using a random allocation software program, the three groups receiving either perceptive rehabilitation (PR-group), mobilization techniques (Mob-group), or neither (the control group, C-group).

NCT ID: NCT03687619 Completed - Clinical trials for Down Syndrome, Trisomy 21

Cognitive Orientation to Daily Occupational Performance and Conductive Education Approaches on Down Syndrome

Start date: March 5, 2019
Phase: N/A
Study type: Interventional

This study will be conducted to investigate and compare the effects of Cognitive Orientation to Daily Occupational Performance (CO-OP) and Conductive Education (CE) on fine motor skills, activity, and participation limitations in children with DS. Children with DS aged 7-18 years will be included. Both CO-OP and CE interventions will last 12 weeks and be conducted for 2 sessions per week in the cross-over randomized study. Following 12-week wash-out period, interventions will be changed for each group.

NCT ID: NCT03651479 Completed - Stroke Clinical Trials

The Comparison of Virtual and Real Boxing Training in Hemiparetic Stroke Patients

Start date: November 10, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effects of virtual and real boxing training in addition to neurodevelopmental training on cognitive status, upper extremity functions, balance and activities of daily living in hemiparetic stroke patients.