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NCT ID: NCT03529682 Not yet recruiting - Clinical trials for Spastic Cerebral Palsy

Circuit Training in Children With Cerebral Palsy

Start date: May 2018
Phase: N/A
Study type: Interventional

The aim of our study is to reveal the results of circuit training to be applied to the children with Cerebral Palsy (CP) for improving their muscular strength and trunk control and also to determine their effects in terms of activity limitations and participation limits.

NCT ID: NCT03495336 Completed - Clinical trials for Cardiovascular Diseases

The Effects of Unfiltered (Turkish) Coffee Consumption on Cardiovascular Risk Parameters

Start date: March 22, 2017
Phase: N/A
Study type: Interventional

Purpose/Objective: The aim of this study is to investigate the impact of boiled unfiltered (Turkish) coffee consumption on the plasma cardiovascular risk parameters of healthy subjects. The study also explores whether two unfiltered boiled (Turkish) coffee beverages that differ in content due to different roasting degrees will differentially affect cardiovascular biomarkers. Methods: In this crossover intervention study, healthy, nonsmoking, habitual Turkish coffee drinkers (n=28) were randomized to consume at least 3 cups of Light (LR) or Dark (DR) roast Turkish coffee brews per day for 4 weeks after a washout period (WO) of 2 weeks. Subsequent to each coffee abstinence period, both groups received the alternative intervention. After the first WO and the coffee intervention periods, anthropometric measures, blood pressure, heart rate and 13 biochemical parameters were collected and dietary records were completed.

NCT ID: NCT03352921 Recruiting - Clinical trials for Sagital Cervical Disorientation

Efficacy Of Clinical Pilates Exercises İn Desk-Based Workers With Sagital Cervical Disorientation

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effects of clinical pilates exercises and home exercise program on postural disorders, pain intensity, normal range of motion, muscle strength, endurance, muscle shortness, joint position sense and functional status in desk workers with sagittal cervical disorientation.

NCT ID: NCT03211559 Completed - Clinical trials for Ankylosing Spondylitis

Clinical Pilates and Aerobic Exercise in Patients With Ankylosing Spondylitis

Start date: October 2015
Phase: N/A
Study type: Interventional

The aim of our study is to investigate the effect of Clinical Pilates Exercises on functional status and quality of life when applied together with aerobic exercise in patients with ankylosing spondylitis (AS).

NCT ID: NCT03198273 Recruiting - Clinical trials for Lumbar Disc Herniation

The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar disc herniation.

NCT ID: NCT03129100 Recruiting - Clinical trials for Axial Spondyloarthritis

A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis

Start date: April 19, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate, in participants having achieved a state of sustained remission, if the ixekizumab treatment groups are superior to the placebo group in maintaining response during the randomized withdrawal-retreatment period in participants with axial spondyloarthritis.

NCT ID: NCT03121222 Completed - Clinical trials for Glutathione Metabolism Anemias

The Effects of N-acetylcysteine on Performance and Redox Homeostasis

Start date: November 1, 2015
Phase: Phase 2
Study type: Interventional

The main objective of the present study was to investigate whether N-acetylcysteine supplementation in individuals with low glutathione levels would confer ergogenic effects by replenishing glutathione levels and by reducing oxidative stress. Towards this aim, investigators sought to exploit the large inter-individual variability in redox biomarker levels. More specifically, investigators screened 100 male participants for glutathione baseline levels in blood and formed three stratified groups according to this value (i.e., low, moderate and high; 12 individuals per group). After by-passing the regression to the mean artefact by performing a second glutathione measurement in the three aforementioned groups, investigators assessed both aerobic and anaerobic physical performance in order to acquire a more comprehensive view about the ergogenic effectiveness of the antioxidant treatment. This was accomplished by implementing three different whole-body physical performance tests (i.e., VO2max test, time trial and Wingate), as opposed to most in vivo studies that either applied isolated body-part exercise tests (e.g., by isokinetic dynamometry) or performed a single exercise test (e.g., time-to-fatigue test). It was hypothesised, that data of the present investigation will bridge the chasm between the scientific (i.e., chronic antioxidant supplementation blunts exercise performance and adaptations) and the community-based (i.e., free radicals should anyway be counteracted by "protective" exogenous antioxidants) truths about the role of antioxidants as ergogenic aids. It was also hypothesised that the results will show that low glutathione levels are linked to decreased aerobic and anaerobic physical performance accompanied by increased levels of oxidative stress and that N-acetylcysteine supplementation will restore both performance and redox homeostasis. Based on the findings of the present investigation, the widespread routine practice of consuming antioxidants during exercise training could be changed and the consumption of antioxidants would be restricted only for those who are deficient in glutathione.

NCT ID: NCT02991781 Not yet recruiting - Asthma Clinical Trials

Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation

Start date: January 2017
Phase: N/A
Study type: Interventional

This study will develop and experimentally test the efficiency of a neurofeedback training protocol vs. varenicline use for smoking cessation.

NCT ID: NCT02962505 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

Continuous Regional Analysis Device for Neonate Lung

Start date: November 2016
Phase: N/A
Study type: Observational

The purpose of the study is to assess whether Electrical Impedance Tomography (EIT) has the potential to optimize the ventilator therapy, validate the effectiveness, efficacy and safety of nursing and medical interventions (endotracheal suctioning, posture changes, surfactant therapy, recruitment manoeuvres, etc.) and for early recognition of complications like pneumothorax and endotracheal tube misplacement. The study design is purely observational.

NCT ID: NCT02734992 Active, not recruiting - Headache Clinical Trials

Acceptance and Commitment Therapy vs Medical Treatment as Usual Wait-list Control for Primary Headache Sufferers

Start date: September 2014
Phase: N/A
Study type: Interventional

Research to date suggests that individuals with headache use avoidance as a way to manage their pain. Despite the wide use of avoidance as a coping mechanism of headache triggers, very little empirical evidence exist to support its effectiveness in headache management. New treatment approaches, such as Acceptance and Commitment Therapy (ACT), emphasize acceptance of headache and valued-living as alternatives to avoidance, have demonstrated preliminary support in helping individuals reduce headache-related disability and improve quality of life. Though, ACT has received empirical support for various chronic pain conditions, very little evidence exists as to its effectiveness for head pain problems. The current study will examine the effects of an ACT-based intervention when added to medical treatment as usual (MTAU) vs. a wait list control group comprised only of MTAU, on improving quality of life and decreasing disability among headache sufferers.