There are about 36818 clinical studies being (or have been) conducted in China. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
Increased production of vasodilating substances such as NO plays an important role in the development of vasoplegic syndrome caused by obstructive jaundice.Methylene blue plays a role in raising blood pressure by inhibiting the vasodilator Nitric Oxide (NO)
Neuromyelitis Optica (NMO)/ Neuromyelitis Optica Spectrum Disorders (NMOSD) is an immune-mediated inflammatory demyelinating disease of the central nervous system mainly involving optic nerve and spinal cord. It is clinically characterized by simultaneous or sequential involvement of the optic nerve and spinal cord, presenting a progressive or remission and relapse course, which can lead to paralysis and blindness. The objective of this study is to provide evidence regarding treat effects and factors related to prognosis which will help physicians better evaluable risk-benefit in NMOSD management and improve patients' outcome.
It is a prospective and observational trial that designed to evaluate the effect of intraoperative indocyanine green angiography (ICGA) on prediction of postoperative necrosis and other complications in patients treated with expanded flaps.
Non-suicidal self-injury (NSSINSSINSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders. This study is expected to complete a multi-center epidemiological survey of non-suicidal self-injury in China, and to study its pathogenesis and intervention methods.
This is a prospective,observational single-center study. The osteoporotic patients requiring posterior lumbar interbody fusion(PLIF) with cages at the lowest fusion segment are prospectively enrolled and followed up. The patients undergoing PLIF with the 3D-printed porous titanium alloy cages are compared with those using PEEK cages. The hypothesis is that the use of 3D-printed porous titanium alloy cages can reduce the rate of pedicle screw loosening and increase the rate of lumbar fusion in osteoporotic patients.
The plasma level of mtDNA in sepsis is affected by continous venovenous hemofiltation（CVVH）
The main objective is to assess the effectiveness and safety of the MitralStitch repair system in patients with moderate to severe and severe mitral regurgitation.
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common childhood sleep disorder with an incidence of 3% . Studies have confirmed that OSAHS can cause multiple systemic dysfunction in children, especially affecting cognitive function . Cognitive function is an important part of human advanced neurological activities, including neurobehavioral functions such as orientation, attention, concentration, alertness, behavior, execution, etc., as well as intelligence and verbal functions such as memory, learning, calculation, language, understanding, judgment, and logic. Reasoning and many other aspects. Impaired cognitive function often means poor academic performance, which is the most concern of parents. However, due to the limitations of cognitive assessment tools, most studies only conduct qualitative research on children's cognition, lack of quantitative research. . The underlying reason is that these studies lack the guidance of systematic intellectual theory and the support of cognitive quantitative assessment tools. At present, no one at home and abroad has systematically and comprehensively studied the cognitive impairment caused by OSAHS based on the most advanced cognitive theory. Modern cognitive science believes that cognition, including human memory, decision, reasoning, classification, and planning, is an ability that can be added to "the treatment may change." Some skill and intelligence of human beings at a certain level of cognitive activity can be trained in the execution of certain practices and in the completion of a plan. Scenes, situational features, and tasks, whether material or symbolic, play an important role in human training techniques. Therefore, evaluable and scientific cognitive function training for individuals is beneficial to the development of cognitive function, especially for the treatment training of patients with cognitive dysfunction. At present, the treatment of OSAHS is mainly for the treatment of primary disease such as oropharyngeal surgery, CPAP, etc. These treatments
Plasma mtDNA analysis aids in predicting pancreatic necrosis in severe acute pancreatitis patients.After the onset of severe acute pancreatitis, pancreatic necrosis and the content of mtDNA in plasma will increase, showing a significant positive correlation.
Based on a new mass spectrometry system, body fluid samples were analyzed to verify the role of metabolite analysis in the diagnosis of pediatric medulloblastoma.