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Jaundice clinical trials

View clinical trials related to Jaundice.

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NCT ID: NCT06329843 Recruiting - Neonatal Jaundice Clinical Trials

Intermountain Inpatient Bilirubin Decision Accuracy Study Using Smartphone-based Measurements by Picterus Jaundice Pro

Start date: February 12, 2024
Phase:
Study type: Observational

The goal of this project is to evaluate the performance of Picterus Jaundice Pro in an American population, including preterm and term newborns and pre- and post- phototherapy.

NCT ID: NCT06280872 Recruiting - Sepsis Clinical Trials

Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns

PhyCordPrem
Start date: February 19, 2024
Phase: N/A
Study type: Interventional

Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid. After vaginal delivery, the umbilical cord is clamped and cut after a delay that allows some of the blood in the umbilical cord and placenta to flow back into the baby. Meanwhile, as the baby breathes for the first time, the lungs fill with air and more fluid is pushed out. However, it does not always work out that way. A baby born prematurely may have breathing problems because of extra fluid staying in the lungs related to the immaturity of the lung structure. Thus, the baby must breathe quicker and harder to get enough oxygen enter into the lungs. The newborn is separated from the mother to provide emergency respiratory support. Although the baby is usually getting better within one or two days, the treatment requires close monitoring, breathing help, and nutritional help as the baby is too tired to suck and swallow milk. Sometimes, the baby cannot recover well and show greater trouble breathing needing intensive care. This further separates the mother and her baby. A possible mean to help the baby to adapt better after a premature birth while staying close to the mother is to delay cord clamping when efficient breathing is established, either spontaneously or after receiving breathing help at birth. In this study, we intend to test this procedure in moderate or late preterm infants and see whether the technique helps the baby to better adapt after birth and to better initiate a deep bond with the mother.

NCT ID: NCT06276738 Not yet recruiting - Pancreatic Cancer Clinical Trials

The LINFU® U.S. Registry in Patients With Clinical Signs and/or Symptoms of Disease

Start date: March 30, 2024
Phase:
Study type: Observational [Patient Registry]

Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC.

NCT ID: NCT06276582 Recruiting - Jaundice, Neonatal Clinical Trials

Screening for Neonatal Jaundice With a Mobile Health Device: a Validation Study in Oaxaca, Mexico.

Start date: January 17, 2023
Phase: N/A
Study type: Interventional

The performance and accuracy of the smartphone application (app) Picterus Jaundice Pro (PicterusJP) will be validated by a cross-sectional study conducted in low resource settings in Mexico. Physics-based and machine learning-based models will be used to analyze the images obtained with the app and its performance will be compared.

NCT ID: NCT06236165 Recruiting - Clinical trials for Hepatic and Post Hepatic Jaundice

Clinical Study Evaluating Efficacy, Safety and Molecular Mechanism of Both N-acetylcysteine and Pentoxifylline Supplementation in Patients With Hepatic and Post Hepatic Jaundice

Start date: February 14, 2024
Phase: Phase 3
Study type: Interventional

Investigating the efficacy, safety, and molecular mechanism of both N-acetylcysteine and Pentoxifylline supplementation in improving elevated direct bilirubin level and liver function tests in patients with hepatic and post-hepatic jaundice.

NCT ID: NCT06232174 Not yet recruiting - Jaundice Clinical Trials

Value of Transcutaneous Bilirubin Devices

Start date: February 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare the value of transcutaneous bilirubin devices versus serum bilirubin in jaundiced neonates

NCT ID: NCT06227624 Completed - Neonatal Jaundice Clinical Trials

Role of Oral Zinc in Reducing Neonatal Indirect Hyperbilirubinemia

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

This study aimed to determine the role of oral zinc in reducing the neonatal indirect hyperbilirubinemia if used concomitant with the standard phototherapy

NCT ID: NCT06209489 Not yet recruiting - Clinical trials for Hyperbilirubinemia, Neonatal

White Cover and Massage Impact on Bilirubin Levels and Phototherapy Duration in Newborns

Start date: February 28, 2024
Phase: N/A
Study type: Interventional

This study aimed to examine the effect of white cover and massage application on newborns' bilirubin level and duration of phototherapy in newborns receiving phototherapy.

NCT ID: NCT06197984 Recruiting - Choledocholithiasis Clinical Trials

Antimicrobial Resistance in Acute Cholangitis

ARISE
Start date: January 8, 2024
Phase:
Study type: Observational [Patient Registry]

This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to identify specific patterns of resistance, assess the effectiveness of current antimicrobial therapies, and explore potential strategies to optimize treatment regimens.

NCT ID: NCT06196164 Not yet recruiting - Clinical trials for Cholangiopancreatography, Endoscopic Retrograde

A RCT of Low MBO Drainage Strategies

Start date: February 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of EUS-BD compared with ERCP-BD in low biliary obstruction caused by periampullary cancer, pancreatic cancer or low bile duct cancer. This is a single center, prospective, randomized-controlled study. The primary endpoint of this study is stent patency time, and secondary endpoints include technical success rate, clinical success rate, operation time, operation related complications rate, reintervention rate, stent patency rate at 6 months, and 1-year postoperative survival rate.